Question 1

Which of the following transfusion reactions demonstrates with coughing,cyanosis,and difficulty breathing?

Accepted Answer

A)  Allergic 
B)  Febrile 
C)  Hemolytic 
D)  TRALI 
A)  Allergic 
B)  Febrile 
C)  Hemolytic 
D)  TRALI D

Question 2

MATCHING
Match the transfusion reaction with the description that best fits.
-Delayed hemolytic

Accepted Answer

A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly F

Question 3

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

Accepted Answer

A)  Rh 
B)  Kell 
C)  Kidd 
D)  ABO 
A)  Rh 
B)  Kell 
C)  Kidd 
D)  ABO D

Question 4

A patient is diagnosed with cardiac insufficiency and needs a red blood cell transfusion.How should the transfusion be administered?

Accepted Answer

A)  The red blood cell unit should be transfused slowly over a 4-hour period. 
B)  The unit should be transfused as whole blood. 
C)  Diuretics should be administered with the unit. 
D)  Transfusion should be avoided. 
A)  The red blood cell unit should be transfused slowly over a 4-hour period. 
B)  The unit should be transfused as whole blood. 
C)  Diuretics should be administered with the unit. 
D)  Transfusion should be avoided.

Question 5

In a delayed hemolytic transfusion reaction,what is a typical DAT result?

Accepted Answer

A)  Negative 
B)  Positive due to C3 
C)  Mixed field positive 
D)  Very strongly positive 
A)  Negative 
B)  Positive due to C3 
C)  Mixed field positive 
D)  Very strongly positive

Question 6

What antibodies cause an anaphylactic transfusion reaction?

Accepted Answer

A)  IgA 
B)  IgG 
C)  IgE 
D)  All of the above 
A)  IgA 
B)  IgG 
C)  IgE 
D)  All of the above

Question 7

Ten days after a 2-unit RBC transfusion,a patient experienced a 2 g/dL drop in hemoglobin and appeared slightly jaundiced.No evidence of bleeding was observed.What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Accepted Answer

A)  Culture the donor unit. 
B)  Compare pretransfusion and posttransfusion ABO and D typing. 
C)  Perform hepatitis B surface antigen test. 
D)  Perform an antibody screen and DAT on the current posttransfusion sample. 
A)  Culture the donor unit. 
B)  Compare pretransfusion and posttransfusion ABO and D typing. 
C)  Perform hepatitis B surface antigen test. 
D)  Perform an antibody screen and DAT on the current posttransfusion sample.

Question 8

Under what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

Accepted Answer

A)  Bacterial contamination of the unit 
B)  Medications administered with the unit 
C)  Red blood cell unit transfused quickly through a leukocyte reduction filter 
D)  All of the above 
A)  Bacterial contamination of the unit 
B)  Medications administered with the unit 
C)  Red blood cell unit transfused quickly through a leukocyte reduction filter 
D)  All of the above

Question 9

MATCHING
Match the transfusion reaction with the description that best fits.
-Urticarial

Accepted Answer

A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 10

Documentation of a transfusion reaction investigation should include all of the following except:

Accepted Answer

A)  posttransfusion patient temperature. 
B)  human leukocyte antigen (HL
A)  typing. 
C)  re-identification of the patient and transfused component. 
D)  collection of a blood sample. 
A)  posttransfusion patient temperature. 
B)  human leukocyte antigen (HL
A)  typing. 
C)  re-identification of the patient and transfused component. 
D)  collection of a blood sample.

Question 11

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

Accepted Answer

A)  Leukocyte-reduced red blood cells 
B)  Packed red blood cells 
C)  Frozen red blood cells 
D)  Whole blood 
A)  Leukocyte-reduced red blood cells 
B)  Packed red blood cells 
C)  Frozen red blood cells 
D)  Whole blood

Question 12

MATCHING
Match the transfusion reaction with the description that best fits.
-Febrile,nonhemolytic

Accepted Answer

A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 13

The use of only male donors as a source of plasma for transfusion is a method to reduce the risk of:

Accepted Answer

A)  allergic reactions 
B)  circulatory overload. 
C)  TRALI. 
D)  febrile reactions. 
A)  allergic reactions 
B)  circulatory overload. 
C)  TRALI. 
D)  febrile reactions.

Question 14

Which of the following transfusion reactions has the highest incidence?

Accepted Answer

A)  Hemolytic reactions due to ABO incompatibility 
B)  Urticarial 
C)  Graft-versus-host disease 
D)  Transfusion-related acute lung injury 
A)  Hemolytic reactions due to ABO incompatibility 
B)  Urticarial 
C)  Graft-versus-host disease 
D)  Transfusion-related acute lung injury

Question 15

MATCHING
Match the transfusion reaction with the description that best fits.
-Acute hemolytic

Accepted Answer

A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly 
A) Prevented by leukocyte-reduced components 
B) Prevented by irradiation of components 
C) Symptoms include hives and itching 
D) Associated with ABO incompatibilities 
E) Caused by donor white cell antibodies
F)Alloantibodies to red cell antigens
G)Can be prevented by transfusion slowly

Question 16

Select the clinical sign that is not associated with a hemolytic transfusion reaction.

Accepted Answer

A)  Disseminated intravascular coagulation 
B)  Renal failure 
C)  Shock 
D)  Graft-versus-host disease 
A)  Disseminated intravascular coagulation 
B)  Renal failure 
C)  Shock 
D)  Graft-versus-host disease

Question 17

Which of the following transfusion reactions can be linked to the administration of whole blood to a patient with cardiac insufficiency?

Accepted Answer

A)  Delayed hemolytic reaction 
B)  Transfusion-related acute lung injury (TRALI) 
C)  Circulatory overload (TACO) 
D)  Febrile nonhemolytic reaction 
A)  Delayed hemolytic reaction 
B)  Transfusion-related acute lung injury (TRALI) 
C)  Circulatory overload (TACO) 
D)  Febrile nonhemolytic reaction

Question 18

What component is indicated for patients who receive directed donations from immediate family members to prevent graft-versus-host transfusion reactions?

Accepted Answer

A)  Irradiated red blood cells 
B)  Packed red blood cells 
C)  Washed red blood cells 
D)  Cytomegalovirus-negative red blood cells 
A)  Irradiated red blood cells 
B)  Packed red blood cells 
C)  Washed red blood cells 
D)  Cytomegalovirus-negative red blood cells

Question 19

A patient has a rise in temperature and chills during a transfusion.The transfusion is stopped,and a posttransfusion blood sample is carefully drawn.What should the transfusion service immediately perform upon receipt of this postreaction sample?

Accepted Answer

A) Perform a clerical check, observe the color of serum and perform an antibody screen 
B)  Perform a clerical check, observe the color of serum and perform a direct antiglobulin test 
C)  Perform an antibody screen and a direct antiglobulin test 
D)  Perform an antibody screen and a crossmatch 
A) Perform a clerical check, observe the color of serum and perform an antibody screen 
B)  Perform a clerical check, observe the color of serum and perform a direct antiglobulin test 
C)  Perform an antibody screen and a direct antiglobulin test 
D)  Perform an antibody screen and a crossmatch

Question 20

What is the cause of posttransfusion purpura?

Accepted Answer

A)  Red cell antibodies 
B)  White cell antibodies 
C)  Platelet antibodies 
D)  Bacterial contamination 
A)  Red cell antibodies 
B)  White cell antibodies 
C)  Platelet antibodies 
D)  Bacterial contamination

Which of the following transfusion reactions demonstrates with coughing,cyanosis,and difficulty breathing?

MATCHING Match the transfusion reaction with the description that best fits. -Delayed hemolytic

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

A patient is diagnosed with cardiac insufficiency and needs a red blood cell transfusion.How should the transfusion be administered?

In a delayed hemolytic transfusion reaction,what is a typical DAT result?

What antibodies cause an anaphylactic transfusion reaction?

Ten days after a 2-unit RBC transfusion,a patient experienced a 2 g/dL drop in hemoglobin and appeared slightly jaundiced.No evidence of bleeding was observed.What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Under what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

MATCHING Match the transfusion reaction with the description that best fits. -Urticarial

Documentation of a transfusion reaction investigation should include all of the following except:

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

MATCHING Match the transfusion reaction with the description that best fits. -Febrile,nonhemolytic

The use of only male donors as a source of plasma for transfusion is a method to reduce the risk of:

Which of the following transfusion reactions has the highest incidence?

MATCHING Match the transfusion reaction with the description that best fits. -Acute hemolytic

Select the clinical sign that is not associated with a hemolytic transfusion reaction.

Which of the following transfusion reactions can be linked to the administration of whole blood to a patient with cardiac insufficiency?

What component is indicated for patients who receive directed donations from immediate family members to prevent graft-versus-host transfusion reactions?

A patient has a rise in temperature and chills during a transfusion.The transfusion is stopped,and a posttransfusion blood sample is carefully drawn.What should the transfusion service immediately perform upon receipt of this postreaction sample?

What is the cause of posttransfusion purpura?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters

Exam 11: Adverse Complications of Transfusions

Which of the following transfusion reactions demonstrates with coughing,cyanosis,and difficulty breathing?

MATCHING Match the transfusion reaction with the description that best fits. -Delayed hemolytic

Which of the following blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?

A patient is diagnosed with cardiac insufficiency and needs a red blood cell transfusion.How should the transfusion be administered?

In a delayed hemolytic transfusion reaction,what is a typical DAT result?

What antibodies cause an anaphylactic transfusion reaction?

Ten days after a 2-unit RBC transfusion,a patient experienced a 2 g/dL drop in hemoglobin and appeared slightly jaundiced.No evidence of bleeding was observed.What tests would be helpful in determining whether the patient is experiencing a delayed hemolytic transfusion reaction?

Under what circumstance would a direct antiglobulin test be negative in the presence of a hemolytic process?

MATCHING Match the transfusion reaction with the description that best fits. -Urticarial

Documentation of a transfusion reaction investigation should include all of the following except:

Which blood product is recommended for transfusions to individuals with a history of febrile nonhemolytic transfusion reactions?

MATCHING Match the transfusion reaction with the description that best fits. -Febrile,nonhemolytic

The use of only male donors as a source of plasma for transfusion is a method to reduce the risk of:

Which of the following transfusion reactions has the highest incidence?

MATCHING Match the transfusion reaction with the description that best fits. -Acute hemolytic

Select the clinical sign that is not associated with a hemolytic transfusion reaction.

Which of the following transfusion reactions can be linked to the administration of whole blood to a patient with cardiac insufficiency?

What component is indicated for patients who receive directed donations from immediate family members to prevent graft-versus-host transfusion reactions?

A patient has a rise in temperature and chills during a transfusion.The transfusion is stopped,and a posttransfusion blood sample is carefully drawn.What should the transfusion service immediately perform upon receipt of this postreaction sample?

What is the cause of posttransfusion purpura?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters