Question 1

When is the immediate-spin or abbreviated crossmatch an acceptable procedure for the recipient?

Accepted Answer

A)  No prior or existing clinically significant antibodies 
B)  Never been pregnant or transfused 
C)  Needs blood before a sample can be obtained 
D)  Using blood from a directed donation 
A)  No prior or existing clinically significant antibodies 
B)  Never been pregnant or transfused 
C)  Needs blood before a sample can be obtained 
D)  Using blood from a directed donation A

Question 2

Given the following red cell antigen frequencies:
K 10%
E 30%
K 90%
P₁ 80%
Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

Accepted Answer

A)  Anti-K 
B)  Anti-E 
C)  Anti-k 
D)  Anti-P₁ 
A)  Anti-K 
B)  Anti-E 
C)  Anti-k 
D)  Anti-P₁ A

Question 3

A patient was admitted to the hospital with acute bleeding.Anti-E was detected in the patient's serum.Four E-negative units of blood were crossmatched for the patient.The units were compatible at immediate-spin and following the antiglobulin test.After the antiglobulin test was performed,IgG-sensitized red cells gave a 2+-agglutination reaction.What is the proper interpretation of this 2+-agglutination reaction?

Accepted Answer

A)  Antihuman globulin washing procedure was adequate. 
B)  IgG-sensitized red cells spontaneously agglutinated. 
C)  Crossmatch was incompatible. 
D)  Patient's anti-E reacted with the IgG-sensitized red cells. 
A)  Antihuman globulin washing procedure was adequate. 
B)  IgG-sensitized red cells spontaneously agglutinated. 
C)  Crossmatch was incompatible. 
D)  Patient's anti-E reacted with the IgG-sensitized red cells. A

Question 4

If the recipient was transfused within the last 3 months,how long from the time of collection can a sample be used for the crossmatch?

Accepted Answer

A)  3 days 
B)  5 days 
C)  7 days 
D)  10 days 
A)  3 days 
B)  5 days 
C)  7 days 
D)  10 days

Question 5

When type O blood is not available for transfusion for a type O recipient,what is the next alternative?

Accepted Answer

A)  Group A red blood cells 
B)  Group AB red blood cells 
C)  Washed group B red blood cells 
D)  None 
A)  Group A red blood cells 
B)  Group AB red blood cells 
C)  Washed group B red blood cells 
D)  None

Question 6

How many units of red blood cells are required to raise the hematocrit of a 70-kg nonbleeding adult man from 24% to 30%?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
A)  1 
B)  2 
C)  3 
D)  4

Question 7

Why is a recipient's antibody screening performed as a component of compatibility testing?

Accepted Answer

A)  Detects red cell alloantibodies 
B)  Detects irregular antigens on the recipient's red cells 
C)  Detects human leukocyte antigen antibodies 
D)  Detects incompatibilities with the donor's red cells 
A)  Detects red cell alloantibodies 
B)  Detects irregular antigens on the recipient's red cells 
C)  Detects human leukocyte antigen antibodies 
D)  Detects incompatibilities with the donor's red cells

Question 8

Select the correct statement regarding the collection of a blood sample for compatibility testing.

Accepted Answer

A)  The sample must be labeled at the bedside. 
B)  The sample requires a new numeric identifier for the patient for each admittance. 
C)  The sample may be labeled at any time in an emergency. 
D)  The sample does not require a means to identify the phlebotomist. 
A)  The sample must be labeled at the bedside. 
B)  The sample requires a new numeric identifier for the patient for each admittance. 
C)  The sample may be labeled at any time in an emergency. 
D)  The sample does not require a means to identify the phlebotomist.

Question 9

The use of the electronic (computer)crossmatch is restricted to recipients who:

Accepted Answer

A)  are group O. 
B)  do not have a clinically significant antibody. 
C)  have had successful transfusions in the past. 
D)  have transfusion history that has been documented in the computer. 
A)  are group O. 
B)  do not have a clinically significant antibody. 
C)  have had successful transfusions in the past. 
D)  have transfusion history that has been documented in the computer.

Question 10

Which of the following tests is not included in routine compatibility testing?

Accepted Answer

A)  ABO phenotyping 
B)  Direct antiglobulin test 
C)  D typing 
D)  Antibody screen 
A)  ABO phenotyping 
B)  Direct antiglobulin test 
C)  D typing 
D)  Antibody screen

Question 11

Which of the following blood products requires a crossmatch before issuing?

Accepted Answer

A)  Group AB fresh frozen plasma that is transfused to a group O 
B)  Human leukocyte antigen-matched platelets 
C)  Cryoprecipitated AHF 
D)  Granulocyte concentrates that have more than 2 mL of red blood cells 
A)  Group AB fresh frozen plasma that is transfused to a group O 
B)  Human leukocyte antigen-matched platelets 
C)  Cryoprecipitated AHF 
D)  Granulocyte concentrates that have more than 2 mL of red blood cells

Question 12

A 29-year-old female was admitted to the emergency room with severe bleeding.The blood type was group AB,D-negative.Six units of RBCs are ordered STAT.Of the following types available in the blood bank,which would be the most preferable for crossmatch?

Accepted Answer

A)  AB, D positive 
B)  A, D negative 
C)  A, D positive 
D)  O, D negative 
A)  AB, D positive 
B)  A, D negative 
C)  A, D positive 
D)  O, D negative

Question 13

A tube was received in the blood bank for crossmatching.The label was torn and the only information that was visible was the patient's last name and the medical record number.Which of the following is an acceptable procedure?

Accepted Answer

A)  Request a recollection of the specimen. 
B)  Call the phlebotomist back to relabel the tube. 
C)  Reprint a label using the MRI as the identifier. 
D)  Use the tube since the MRI is visible. 
A)  Request a recollection of the specimen. 
B)  Call the phlebotomist back to relabel the tube. 
C)  Reprint a label using the MRI as the identifier. 
D)  Use the tube since the MRI is visible.

Question 14

What can be done to increase the sensitivity of the antibody screen in a compatibility test?

Accepted Answer

A)  Extend the incubation time. 
B)  Increase the serum-to-cell ratio. 
C)  Use an enhancement such as polyethylene glycol. 
D)  All of the above are correct. 
A)  Extend the incubation time. 
B)  Increase the serum-to-cell ratio. 
C)  Use an enhancement such as polyethylene glycol. 
D)  All of the above are correct.

Question 15

An antibody screen on a patient with a prior history of transfusion was negative.The patient had an indication to perform an AHG crossmatch on file.The crossmatch was incompatible with 1 of 5 units selected at AHG phase.What is the next step in the investigation?

Accepted Answer

A)  Perform a prewarm procedure for crossmatching 
B)  Perform a direct antiglobulin test on the incompatible unit 
C)  Redraw the patient and begin a new crossmatch 
D)  Crossmatch a new unit and discard the incompatible unit 
A)  Perform a prewarm procedure for crossmatching 
B)  Perform a direct antiglobulin test on the incompatible unit 
C)  Redraw the patient and begin a new crossmatch 
D)  Crossmatch a new unit and discard the incompatible unit

Question 16

How long following transfusion must the recipient's sample be stored?

Accepted Answer

A)  5 days 
B)  7 days 
C)  10 days 
D)  14 days 
A)  5 days 
B)  7 days 
C)  10 days 
D)  14 days

Question 17

A recipient is group O with the following Rh phenotype: D+C+c-E+e+.
If this recipient is transfused with red blood cells from six random group O D-positive donors,what Rh alloantibody could this patient produce as a result of transfusion?

Accepted Answer

A)  Anti-E 
B)  Anti-C 
C)  Anti-c 
D)  Anti-D 
A)  Anti-E 
B)  Anti-C 
C)  Anti-c 
D)  Anti-D

Question 18

If not stored in a monitored refrigerator,how long can RBC units remain outside the transfusion service to allow reissue?

Accepted Answer

A)  15 minutes 
B)  30 minutes 
C)  45 minutes 
D)  60 minutes 
A)  15 minutes 
B)  30 minutes 
C)  45 minutes 
D)  60 minutes

Question 19

A donor unit with a positive DAT would cause reactions at what phase of the crossmatch?

Accepted Answer

A)  Immediate-spin 
B)  Antiglobulin 
C)  None; it would be compatible 
D)  All phases 
A)  Immediate-spin 
B)  Antiglobulin 
C)  None; it would be compatible 
D)  All phases

Question 20

A group O patient was crossmatched with group B red blood cells.What phase of the crossmatch will first detect this incompatibility?

Accepted Answer

A)  Immediate-spin 
B)  37° C low-ionic strength solution 
C)  Indirect antiglobulin 
D)  None of them; unit is compatible 
A)  Immediate-spin 
B)  37° C low-ionic strength solution 
C)  Indirect antiglobulin 
D)  None of them; unit is compatible

When is the immediate-spin or abbreviated crossmatch an acceptable procedure for the recipient?

Given the following red cell antigen frequencies: K 10% E 30% K 90% P₁ 80% Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

If the recipient was transfused within the last 3 months,how long from the time of collection can a sample be used for the crossmatch?

When type O blood is not available for transfusion for a type O recipient,what is the next alternative?

How many units of red blood cells are required to raise the hematocrit of a 70-kg nonbleeding adult man from 24% to 30%?

Why is a recipient's antibody screening performed as a component of compatibility testing?

Select the correct statement regarding the collection of a blood sample for compatibility testing.

The use of the electronic (computer)crossmatch is restricted to recipients who:

Which of the following tests is not included in routine compatibility testing?

Which of the following blood products requires a crossmatch before issuing?

A 29-year-old female was admitted to the emergency room with severe bleeding.The blood type was group AB,D-negative.Six units of RBCs are ordered STAT.Of the following types available in the blood bank,which would be the most preferable for crossmatch?

A tube was received in the blood bank for crossmatching.The label was torn and the only information that was visible was the patient's last name and the medical record number.Which of the following is an acceptable procedure?

What can be done to increase the sensitivity of the antibody screen in a compatibility test?

An antibody screen on a patient with a prior history of transfusion was negative.The patient had an indication to perform an AHG crossmatch on file.The crossmatch was incompatible with 1 of 5 units selected at AHG phase.What is the next step in the investigation?

How long following transfusion must the recipient's sample be stored?

A recipient is group O with the following Rh phenotype: D+C+c-E+e+. If this recipient is transfused with red blood cells from six random group O D-positive donors,what Rh alloantibody could this patient produce as a result of transfusion?

If not stored in a monitored refrigerator,how long can RBC units remain outside the transfusion service to allow reissue?

A donor unit with a positive DAT would cause reactions at what phase of the crossmatch?

A group O patient was crossmatched with group B red blood cells.What phase of the crossmatch will first detect this incompatibility?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters

Exam 9: Compatibility Testing

When is the immediate-spin or abbreviated crossmatch an acceptable procedure for the recipient?

Given the following red cell antigen frequencies: K 10% E 30% K 90% P₁ 80% Which of the following red cell alloantibodies would be responsible for incompatible crossmatches with one 1 of 10 random donor units?

If the recipient was transfused within the last 3 months,how long from the time of collection can a sample be used for the crossmatch?

When type O blood is not available for transfusion for a type O recipient,what is the next alternative?

How many units of red blood cells are required to raise the hematocrit of a 70-kg nonbleeding adult man from 24% to 30%?

Why is a recipient's antibody screening performed as a component of compatibility testing?

Select the correct statement regarding the collection of a blood sample for compatibility testing.

The use of the electronic (computer)crossmatch is restricted to recipients who:

Which of the following tests is not included in routine compatibility testing?

Which of the following blood products requires a crossmatch before issuing?

A 29-year-old female was admitted to the emergency room with severe bleeding.The blood type was group AB,D-negative.Six units of RBCs are ordered STAT.Of the following types available in the blood bank,which would be the most preferable for crossmatch?

A tube was received in the blood bank for crossmatching.The label was torn and the only information that was visible was the patient's last name and the medical record number.Which of the following is an acceptable procedure?

What can be done to increase the sensitivity of the antibody screen in a compatibility test?

An antibody screen on a patient with a prior history of transfusion was negative.The patient had an indication to perform an AHG crossmatch on file.The crossmatch was incompatible with 1 of 5 units selected at AHG phase.What is the next step in the investigation?

How long following transfusion must the recipient's sample be stored?

A recipient is group O with the following Rh phenotype: D+C+c-E+e+. If this recipient is transfused with red blood cells from six random group O D-positive donors,what Rh alloantibody could this patient produce as a result of transfusion?

If not stored in a monitored refrigerator,how long can RBC units remain outside the transfusion service to allow reissue?

A donor unit with a positive DAT would cause reactions at what phase of the crossmatch?

A group O patient was crossmatched with group B red blood cells.What phase of the crossmatch will first detect this incompatibility?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

ABO and H Blood Group Systems and Secretor Status

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters