Question 1

A patient's red cells are agglutinated by anti-B,but not by anti-A.What is this patient's ABO phenotype?

Accepted Answer

A)  Group B 
B)  Group O 
C)  Group AB 
D)  Group A 
A)  Group B 
B)  Group O 
C)  Group AB 
D)  Group A A

Question 2

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

Accepted Answer

A)  Group B packed cells to a group O recipient 
B)  Group A packed red cells to a group AB recipient 
C)  Group AB plasma to a group A recipient 
D)  Group AB plasma to a group O recipient 
A)  Group B packed cells to a group O recipient 
B)  Group A packed red cells to a group AB recipient 
C)  Group AB plasma to a group A recipient 
D)  Group AB plasma to a group O recipient A

Question 3

According to Landsteiner's rule (law),what ABO antibody will be detected in a group A individual's serum?

Accepted Answer

A)  Anti-A 
B)  Anti-B 
C)  Anti-A,B 
D)  None 
A)  Anti-A 
B)  Anti-B 
C)  Anti-A,B 
D)  None B

Question 4

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery.The forward type demonstrates as a group A,whereas the reverse type appears to be group AB.What is the most likely cause of the discrepancy?

Accepted Answer

A)  Contaminated reagent antisera 
B)  Rouleaux formation 
C)  That the patient has autoantibodies 
D)  That patient has low-titer isoagglutinins 
A)  Contaminated reagent antisera 
B)  Rouleaux formation 
C)  That the patient has autoantibodies 
D)  That patient has low-titer isoagglutinins

Question 5

MATCHING
Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group A

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 6

MATCHING
Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group O

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 7

A group A man marries a group AB woman.The father of the group A man was group O.What possible ABO phenotypes could be expected in the offspring?

Accepted Answer

A)  Groups A, B, AB, and O 
B)  Groups A and B 
C)  Groups A, B, and AB 
D)  Groups A and AB 
A)  Groups A, B, AB, and O 
B)  Groups A and B 
C)  Groups A, B, and AB 
D)  Groups A and AB

Question 8

Why is it sometimes necessary to distinguish A₁ and A₂ blood types?

Accepted Answer

A)  To resolve a discrepancy between the forward and reverse typing 
B)  To prevent A1 recipients from receiving A2 blood 
C)  To determine the secretor status of group A individuals 
D)  To prevent hemolytic disease of the newborn 
A)  To resolve a discrepancy between the forward and reverse typing 
B)  To prevent A1 recipients from receiving A2 blood 
C)  To determine the secretor status of group A individuals 
D)  To prevent hemolytic disease of the newborn

Question 9

Most "naturally occurring" ABO system antibodies fall into which immunoglobulin class?

Accepted Answer

A)  IgA 
B)  IgM 
C)  IgE 
D)  IgG 
A)  IgA 
B)  IgM 
C)  IgE 
D)  IgG

Question 10

Approximately what is the percentage of individuals who demonstrate H in their saliva?

Accepted Answer

A)  15% 
B)  50% 
C)  80% 
D)  98% 
A)  15% 
B)  50% 
C)  80% 
D)  98%

Question 11

Predict the agglutination reaction of red cells from a Bombay phenotype when combined with anti-H lectin.

Accepted Answer

A)  Strong 4+ 
B)  Mixed field 
C)  Weak 1+ 
D)  Negative 
A)  Strong 4+ 
B)  Mixed field 
C)  Weak 1+ 
D)  Negative

Question 12

MATCHING
Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Bombay

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 13

MATCHING
Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-Group B

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 14

What percentage of the group A population are type as A₂?

Accepted Answer

A)  1% 
B)  10% 
C)  20% 
D)  35% 
A)  1% 
B)  10% 
C)  20% 
D)  35%

Question 15

Given the following ABO phenotyping data:
 
What could be a plausible explanation for this discrepancy?

Accepted Answer

A)  T-activation of red cells 
B)  Group O blood products given to group A 
C)  Rouleaux formation 
D)  Positive direct antiglobulin test 
A)  T-activation of red cells 
B)  Group O blood products given to group A 
C)  Rouleaux formation 
D)  Positive direct antiglobulin test

Question 16

What ABO phenotype would agglutinate in the presence of anti-A,B produced by group O individuals?

Accepted Answer

A)  A only 
B)  B only 
C)  A and B 
D)  O only 
A)  A only 
B)  B only 
C)  A and B 
D)  O only

Question 17

A recipient with group A phenotype requires a transfusion of 2 units of frozen plasma.Which of the following types are appropriate to select for transfusion?

Accepted Answer

A)  AB and B 
B)  B and A 
C)  O and A 
D)  AB and A 
A)  AB and B 
B)  B and A 
C)  O and A 
D)  AB and A

Question 18

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

Accepted Answer

A)  Wash patient cells with warm saline. 
B)  Use polyclonal typing reagents. 
C)  Perform an autocontrol. 
D)  Incubate tubes at room temperature or 4° C with an autocontrol. 
A)  Wash patient cells with warm saline. 
B)  Use polyclonal typing reagents. 
C)  Perform an autocontrol. 
D)  Incubate tubes at room temperature or 4° C with an autocontrol.

Question 19

MATCHING
Match the immunodominant sugar that corresponds to the ABO system group or antigen.
-H antigen

Accepted Answer

A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above 
A) D-galactose 
B) L-fucose 
C) N-acetylgalactosamine 
D) None of the above

Question 20

Which ABO phenotype selection contains the most H antigen and the least H antigen,respectively,on the red cell's surface?

Accepted Answer

A)  O, A1B 
B)  A2, A1B 
C)  B, A 
D)  A1B, O 
A)  O, A1B 
B)  A2, A1B 
C)  B, A 
D)  A1B, O

A patient's red cells are agglutinated by anti-B,but not by anti-A.What is this patient's ABO phenotype?

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

According to Landsteiner's rule (law),what ABO antibody will be detected in a group A individual's serum?

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery.The forward type demonstrates as a group A,whereas the reverse type appears to be group AB.What is the most likely cause of the discrepancy?

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group A

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group O

A group A man marries a group AB woman.The father of the group A man was group O.What possible ABO phenotypes could be expected in the offspring?

Why is it sometimes necessary to distinguish A₁ and A₂ blood types?

Most "naturally occurring" ABO system antibodies fall into which immunoglobulin class?

Approximately what is the percentage of individuals who demonstrate H in their saliva?

Predict the agglutination reaction of red cells from a Bombay phenotype when combined with anti-H lectin.

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Bombay

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group B

What percentage of the group A population are type as A₂?

Given the following ABO phenotyping data: What could be a plausible explanation for this discrepancy?

What ABO phenotype would agglutinate in the presence of anti-A,B produced by group O individuals?

A recipient with group A phenotype requires a transfusion of 2 units of frozen plasma.Which of the following types are appropriate to select for transfusion?

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -H antigen

Which ABO phenotype selection contains the most H antigen and the least H antigen,respectively,on the red cell's surface?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters

Exam 5: ABO and H Blood Group Systems and Secretor Status

A patient's red cells are agglutinated by anti-B,but not by anti-A.What is this patient's ABO phenotype?

Which of the following situations is most likely to cause intravascular hemolysis when an incompatible transfusion is given?

According to Landsteiner's rule (law),what ABO antibody will be detected in a group A individual's serum?

A blood sample from a 90-year-old man was submitted to the blood bank for a type and screen before surgery.The forward type demonstrates as a group A,whereas the reverse type appears to be group AB.What is the most likely cause of the discrepancy?

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group A

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group O

A group A man marries a group AB woman.The father of the group A man was group O.What possible ABO phenotypes could be expected in the offspring?

Why is it sometimes necessary to distinguish A₁ and A₂ blood types?

Most "naturally occurring" ABO system antibodies fall into which immunoglobulin class?

Approximately what is the percentage of individuals who demonstrate H in their saliva?

Predict the agglutination reaction of red cells from a Bombay phenotype when combined with anti-H lectin.

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Bombay

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -Group B

What percentage of the group A population are type as A₂?

Given the following ABO phenotyping data: What could be a plausible explanation for this discrepancy?

What ABO phenotype would agglutinate in the presence of anti-A,B produced by group O individuals?

A recipient with group A phenotype requires a transfusion of 2 units of frozen plasma.Which of the following types are appropriate to select for transfusion?

Select the appropriate strategy if the results of red cell and serum testing in the ABO typing procedure have negative agglutination reactions.

MATCHING Match the immunodominant sugar that corresponds to the ABO system group or antigen. -H antigen

Which ABO phenotype selection contains the most H antigen and the least H antigen,respectively,on the red cell's surface?

Quality Assurance and Regulation of the Blood Industry and Safety Issues in the Blood Bank

Immunology: Basic Principles and Applications in the Blood Bank

Blood Banking Reagents: Overview and Applications

Genetic Principles in Blood Banking

Rh Blood Group System

Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Platelet Antigens

Antibody Detection and Identification

Compatibility Testing

Blood Bank Automation for Transfusion Services

Adverse Complications of Transfusions

Hemolytic Disease of the Fetus and Newborn

Donor Selection and Phlebotomy

Testing of Donor Blood

Blood Component Preparation and Therapy

Transfusion Therapy in Selected Patients

Filters