Question 1

Match the phases of drug testing with the appropriate description.
-Phase I

Accepted Answer

A) This phase lasts about 2 years. The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years. The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug. 
A) This phase lasts about 2 years. The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years. The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug.

Question 2

Human immunodeficiency virus can enter the body with cells associated with HIV.

Accepted Answer

A) True 
 B)False

Question 3

Match the disorders with the appropriate description. (Use each answer only once.)
-Bruton's disorder

Accepted Answer

A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens 
A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens

Question 4

Match the disorders with the appropriate description. (Use each answer only once.)
-DiGeorge syndrome

Accepted Answer

A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens 
A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens

Question 5

Match the phases of drug testing with the appropriate description.
-Phase II

Accepted Answer

A) This phase lasts about 2 years. The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years. The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug. 
A) This phase lasts about 2 years. The number of volunteers is 100 to 300 persons with the disease to assess the effectiveness of a drug and to observe for adverse side reactions. 
B) This phase lasts about 1 year and includes 20 to 80 healthy volunteers who are tested for the safety of new drug. 
C) This phase lasts about 3 years. The number of patients with a specific disease is 1000 to 3000 to further verify effectiveness and identify any specific negative side effects of the drug.

Question 6

The human immunodeficiency virus (HIV) attaches itself to receptor sites by means of

Accepted Answer

A) p24. 
B) p31. 
C) gp120. 
D) gp160. 
A) p24. 
B) p31. 
C) gp120. 
D) gp160.

Question 7

Match the disorders with the appropriate description. (Use each answer only once.)
-Duncan's disease

Accepted Answer

A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens 
A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens

Question 8

In addition to lymphocytes, ___________ and skin cells can be infected by HIV.

Accepted Answer

A) macrophages 
B) monocytes 
C) cells in the lymph nodes 
D) All of the above. 
A) macrophages 
B) monocytes 
C) cells in the lymph nodes 
D) All of the above.

Question 9

In HIV infections, a window period of seronegativity extends from the time of initial infection up to

Accepted Answer

A) 2 weeks. 
B) 2 to 6 weeks or longer. 
C) 6 to 12 weeks or longer. 
D) 4 to 8 months or longer. 
A) 2 weeks. 
B) 2 to 6 weeks or longer. 
C) 6 to 12 weeks or longer. 
D) 4 to 8 months or longer.

Question 10

Match the disorders with the appropriate description. (Use each answer only once.)
-Wiskott-Aldrich syndrome

Accepted Answer

A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens 
A) Inadequate response to Epstein-Barr virus 
B) T cell defect 
C) Likely to be confused with pediatric AIDS 
D) Low levels of antibodies 
E) Poor humoral response to bacterial polysaccharide antigens

Question 11

Which is the first detectable viral antibody in the blood of a patient with HIV infection?

Accepted Answer

A) p24 
B) gp41 
C) gp120 
D) gp160 
A) p24 
B) gp41 
C) gp120 
D) gp160

Exam 24: Primary and Acquired Immune Deficiency Syndromes

Match the phases of drug testing with the appropriate description. -Phase I

Human immunodeficiency virus can enter the body with cells associated with HIV.

Match the disorders with the appropriate description. (Use each answer only once.) -Bruton's disorder

Match the disorders with the appropriate description. (Use each answer only once.) -DiGeorge syndrome

Match the phases of drug testing with the appropriate description. -Phase II

The human immunodeficiency virus (HIV) attaches itself to receptor sites by means of

Match the disorders with the appropriate description. (Use each answer only once.) -Duncan's disease

In addition to lymphocytes, ___________ and skin cells can be infected by HIV.

In HIV infections, a window period of seronegativity extends from the time of initial infection up to

Match the disorders with the appropriate description. (Use each answer only once.) -Wiskott-Aldrich syndrome

Which is the first detectable viral antibody in the blood of a patient with HIV infection?

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Rapid Testing

Precipitation and Particle Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Flow Cytometry

Molecular Laboratory Techniques

Infectious Diseases: Traditional and Alternate Diagnostic Techniques

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Hypersensitivity Reactions

Immunoproliferative Disorders

Tolerance, Autoimmunity, and Autoimmune Diseases

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Transplantation: Hla, Solid Organ, and Hematopoietic Stem Cells

Tumor Immunology and Up-To-Date Applications of Next-Generation Sequencing

Primer on Vaccines

Filters