Question 1

The components involved in a positive skin test for tuberculosis (TB) are

Accepted Answer

A) T lymphocytes and macrophages. 
B) segmented neutrophils and monocytes. 
C) B lymphocytes and macrophages. 
D) IgE antibodies. 
A) T lymphocytes and macrophages. 
B) segmented neutrophils and monocytes. 
C) B lymphocytes and macrophages. 
D) IgE antibodies. A

Question 2

The Arthus reaction is associated with the immune phenomenon of

Accepted Answer

A) deposition of immune complexes in blood vessels. 
B) release of histamine from tissue basophils. 
C) destruction of body tissue by cytotoxic T lymphocytes. 
D) phagocytosis of IgG-coated erythrocytes. 
A) deposition of immune complexes in blood vessels. 
B) release of histamine from tissue basophils. 
C) destruction of body tissue by cytotoxic T lymphocytes. 
D) phagocytosis of IgG-coated erythrocytes. A

Question 3

-Asthma is an example of a _____________ hypersensitivity reaction.

Accepted Answer

A) type I 
B) type II 
C) type III 
D) type IV 
A) type I 
B) type II 
C) type III 
D) type IV A

Question 4

Match the terms with the appropriate description.
-Immediate hypersensitivity

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 5

Immune complex reactions can

Accepted Answer

A) suppress or augment the immune response. 
B) inhibit tumor cell destruction. 
C) be deposited in blood vessel walls, glomerular membranes, and other sites. 
D) All of the above. 
A) suppress or augment the immune response. 
B) inhibit tumor cell destruction. 
C) be deposited in blood vessel walls, glomerular membranes, and other sites. 
D) All of the above.

Question 6

Match the terms with the appropriate description.
-Anaphylactoid reaction

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 7

-Hemolytic disease of the newborn is an example of a ____________ hypersensitivity reaction.

Accepted Answer

A) type I 
B) type II 
C) type III 
D) type IV 
A) type I 
B) type II 
C) type III 
D) type IV

Question 8

Histamine can

Accepted Answer

A) lead to constriction of bronchial smooth muscle. 
B) exert an anticoagulant effect. 
C) cause decreased capillary permeability. 
D) enhance opsonization in phagocytosis. 
A) lead to constriction of bronchial smooth muscle. 
B) exert an anticoagulant effect. 
C) cause decreased capillary permeability. 
D) enhance opsonization in phagocytosis.

Question 9

Match the terms with the appropriate description.
-Immunization or sensitization

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 10

All of the following are examples of Type II hypersensitivity reactions except

Accepted Answer

A) Farmer's lung and the Arthus reaction. 
B) immediate transfusion reactions and Hemolytic disease of the newborn (HDN). 
C) antibody-dependent, cell-mediated cytotoxicity involving NK cells or macrophages expressing Fc receptors. 
D) antireceptor antibodies such as those expressed in autoimmune thyroid disease. 
A) Farmer's lung and the Arthus reaction. 
B) immediate transfusion reactions and Hemolytic disease of the newborn (HDN). 
C) antibody-dependent, cell-mediated cytotoxicity involving NK cells or macrophages expressing Fc receptors. 
D) antireceptor antibodies such as those expressed in autoimmune thyroid disease.

Question 11

Match the terms with the appropriate description.
-Delayed hypersensitivity

Accepted Answer

A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction 
A) Cell-mediated 
B) Antibody-mediated 
C) Dependent on the host's response to a subsequent exposure of antigen 
D) Not mediated by antigen-antibody interaction

Question 12

Cell-mediated immunity is responsible for

Accepted Answer

A) contact sensitivity. 
B) elimination of tumor cells bearing neoantigens. 
C) rejection of foreign graft tissue. 
D) all of the above. 
A) contact sensitivity. 
B) elimination of tumor cells bearing neoantigens. 
C) rejection of foreign graft tissue. 
D) all of the above.

Question 13

Anaphylaxis is characterized by all the following statements except

Accepted Answer

A) it can cause death caused by asphyxiation. 
B) there is massive release of histamine from mast cells and basophils. 
C) there was prior sensitization to an allergen. 
D) it is associated with a significant increase in eosinophils in the circulating blood. 
A) it can cause death caused by asphyxiation. 
B) there is massive release of histamine from mast cells and basophils. 
C) there was prior sensitization to an allergen. 
D) it is associated with a significant increase in eosinophils in the circulating blood.

Question 14

Type I hypersensitivity reactions are characterized by

Accepted Answer

A) activation of complement. 
B) antigen cross-links with IgE on mast cells. 
C) being potentially fatal. 
D) Both B and C. 
A) activation of complement. 
B) antigen cross-links with IgE on mast cells. 
C) being potentially fatal. 
D) Both B and C.

Exam 25: Hypersensitivity Reactions

The components involved in a positive skin test for tuberculosis (TB) are

The Arthus reaction is associated with the immune phenomenon of

-Asthma is an example of a _____________ hypersensitivity reaction.

Match the terms with the appropriate description. -Immediate hypersensitivity

Immune complex reactions can

Match the terms with the appropriate description. -Anaphylactoid reaction

-Hemolytic disease of the newborn is an example of a ____________ hypersensitivity reaction.

Histamine can

Match the terms with the appropriate description. -Immunization or sensitization

All of the following are examples of Type II hypersensitivity reactions except

Match the terms with the appropriate description. -Delayed hypersensitivity

Cell-mediated immunity is responsible for

Anaphylaxis is characterized by all the following statements except

Type I hypersensitivity reactions are characterized by

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Rapid Testing

Precipitation and Particle Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Flow Cytometry

Molecular Laboratory Techniques

Infectious Diseases: Traditional and Alternate Diagnostic Techniques

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Primary and Acquired Immune Deficiency Syndromes

Immunoproliferative Disorders

Tolerance, Autoimmunity, and Autoimmune Diseases

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Transplantation: Hla, Solid Organ, and Hematopoietic Stem Cells

Tumor Immunology and Up-To-Date Applications of Next-Generation Sequencing

Primer on Vaccines

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