Question 1

Match the terms with the appropriate definition.
-Xenograft

Accepted Answer

A) Graft between individuals of different species (e.g., pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g., skin, hair, bone) 
C) Graft between genetically different recipient and donor of the same species; grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g., kidney transplant between monozygous twins) 
A) Graft between individuals of different species (e.g., pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g., skin, hair, bone) 
C) Graft between genetically different recipient and donor of the same species; grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g., kidney transplant between monozygous twins)

Question 2

Class II transplant antigens are expressed on

Accepted Answer

A) B lymphocytes. 
B) activated T lymphocytes. 
C) macrophages. 
D) All of the above. 
A) B lymphocytes. 
B) activated T lymphocytes. 
C) macrophages. 
D) All of the above.

Question 3

Potential graft-versus-host disease (GVHD) has all the following factor requirements except

Accepted Answer

A) a source of immunocompetent T lymphocytes. 
B) a source of immunocompetent B lymphocytes. 
C) age of the blood product. 
D) inability to reject donor cells. 
A) a source of immunocompetent T lymphocytes. 
B) a source of immunocompetent B lymphocytes. 
C) age of the blood product. 
D) inability to reject donor cells.

Question 4

The major histocompatibility complex (MHC) D region codes for ________ molecules.

Accepted Answer

A) class I 
B) class II 
C) class III 
D) All of the above. 
A) class I 
B) class II 
C) class III 
D) All of the above.

Question 5

Chronic rejection is

Accepted Answer

A) cell-mediated. 
B) humoral (antibody)-mediated. 
C) either a or B 
D) Both A and B. 
A) cell-mediated. 
B) humoral (antibody)-mediated. 
C) either a or B 
D) Both A and B.

Question 6

Match the terms with the appropriate definition.
-Syngraft

Accepted Answer

A) Graft between individuals of different species (e.g., pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g., skin, hair, bone) 
C) Graft between genetically different recipient and donor of the same species; grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g., kidney transplant between monozygous twins) 
A) Graft between individuals of different species (e.g., pig heart valve to a human heart) 
B) Graft transferred from one position to another in the same individual (e.g., skin, hair, bone) 
C) Graft between genetically different recipient and donor of the same species; grafted donor tissue or organ contains antigens not present in recipient 
D) Graft transplanted between different but identical recipient and donor (e.g., kidney transplant between monozygous twins)

Question 7

Which of the following classes of MHC antigens is necessary for antigen recognition by CD4+ T lymphocytes?

Accepted Answer

A) Class I 
B) Class II 
C) Both class I and class II 
D) Neither class I nor class II 
A) Class I 
B) Class II 
C) Both class I and class II 
D) Neither class I nor class II

Question 8

Which of the following antigens is an MHC class II antigen?

Accepted Answer

A) HLA-A 
B) HLA-DQ 
C) HLA-DR 
D) Both B and C. 
A) HLA-A 
B) HLA-DQ 
C) HLA-DR 
D) Both B and C.

Question 9

The stronger the antigen difference, the more severe the graft-versus-host reaction.

Accepted Answer

A) True 
 B)False

Question 10

The major histocompatibility complex (MHC) is located on

Accepted Answer

A) chromosome 3. 
B) chromosome 6. 
C) chromosome 21. 
D) chromosome 22. 
A) chromosome 3. 
B) chromosome 6. 
C) chromosome 21. 
D) chromosome 22.

Exam 30: Transplantation: Hla, Solid Organ, and Hematopoietic Stem Cells

Match the terms with the appropriate definition. -Xenograft

Class II transplant antigens are expressed on

Potential graft-versus-host disease (GVHD) has all the following factor requirements except

The major histocompatibility complex (MHC) D region codes for ________ molecules.

Chronic rejection is

Match the terms with the appropriate definition. -Syngraft

Which of the following classes of MHC antigens is necessary for antigen recognition by CD4+ T lymphocytes?

Which of the following antigens is an MHC class II antigen?

The stronger the antigen difference, the more severe the graft-versus-host reaction.

The major histocompatibility complex (MHC) is located on

An Overview of Immunology

Antigens and Antibodies

Cells and Cellular Activities of the Immune System: Granulocytes and Mononuclear Cells

Cells and Cellular Activities of the Immune System: Lymphocytes and Plasma Cells

Soluble Mediators of the Immune System

Safety in the Immunology-Serology Laboratory

Quality Assurance and Quality Control

Basic Serologic Laboratory Techniques

Rapid Testing

Precipitation and Particle Agglutination Methods

Electrophoresis Techniques

Labeling Techniques in Immunoassay

Flow Cytometry

Molecular Laboratory Techniques

Infectious Diseases: Traditional and Alternate Diagnostic Techniques

Streptococcal Infections

Syphilis

Vector-Borne Diseases

Toxoplasmosis

Cytomegalovirus

Infectious Mononucleosis

Viral Hepatitis

Rubella and Rubeola Infections

Primary and Acquired Immune Deficiency Syndromes

Hypersensitivity Reactions

Immunoproliferative Disorders

Tolerance, Autoimmunity, and Autoimmune Diseases

Systemic Lupus Erythematosus

Rheumatoid Arthritis

Tumor Immunology and Up-To-Date Applications of Next-Generation Sequencing

Primer on Vaccines

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