Question 1

Most repressor proteins are allosteric. Which of the following molecules binds with the repressor to alter its conformation and therefore affect its function?

Accepted Answer

A)  inducer 
B)  promoter 
C)  transcription factor 
D)  cAMP 
A)  inducer 
B)  promoter 
C)  transcription factor 
D)  cAMP

Question 2

Which of the following conditions is most likely to cause the lactose operon to be transcribed?

Accepted Answer

A)  There is more glucose in the cell than lactose. 
B)  There is glucose but no lactose in the cell. 
C)  The cyclic AMP and lactose levels are both high within the cell. 
D)  The cAMP level is high and the lactose level is low. 
A)  There is more glucose in the cell than lactose. 
B)  There is glucose but no lactose in the cell. 
C)  The cyclic AMP and lactose levels are both high within the cell. 
D)  The cAMP level is high and the lactose level is low.

Question 3

A researcher found a method she could use to manipulate and quantify phosphorylation and methylation in embryonic cells in culture. One of her colleagues suggested she try increased methylation of cytosine (C)nucleotides in the DNA of promoters of a mammalian system. Which of the following results would she most likely see?

Accepted Answer

A)  decreased chromatin condensation 
B)  activation of histone tails for enzymatic function 
C)  higher levels of transcription of certain genes 
D)  inactivation of the selected genes 
A)  decreased chromatin condensation 
B)  activation of histone tails for enzymatic function 
C)  higher levels of transcription of certain genes 
D)  inactivation of the selected genes

Question 4

Which of the following statements best describes the characteristics of siRNA?

Accepted Answer

A)  a double-stranded RNA, one of whose strands can complement and inactivate a sequence of mRNA 
B)  a single-stranded RNA that can, where it has internal complementary base pairs, fold into cloverleaf patterns 
C)  a double-stranded RNA that is formed by cleavage of hairpin loops in a larger precursor 
D)  a portion of rRNA that allows it to bind to several ribosomal proteins in forming large or small subunits 
A)  a double-stranded RNA, one of whose strands can complement and inactivate a sequence of mRNA 
B)  a single-stranded RNA that can, where it has internal complementary base pairs, fold into cloverleaf patterns 
C)  a double-stranded RNA that is formed by cleavage of hairpin loops in a larger precursor 
D)  a portion of rRNA that allows it to bind to several ribosomal proteins in forming large or small subunits

Question 5

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the promoter for the lac operon to the region between the beta galactosidase (lacZ)gene and the permease (lacY)gene, which of the following results would be most likely?

Accepted Answer

A)  The three genes of the lac operon will be expressed normally. 
B)  RNA polymerase will no longer transcribe permease. 
C)  The operon will still transcribe the lacZ and lacY genes, but the mRNA will not be translated. 
D)  Beta galactosidase will not be produced. 
A)  The three genes of the lac operon will be expressed normally. 
B)  RNA polymerase will no longer transcribe permease. 
C)  The operon will still transcribe the lacZ and lacY genes, but the mRNA will not be translated. 
D)  Beta galactosidase will not be produced.

Question 6

Which of the following methods is utilized by eukaryotes to control their gene expression that is different from the type of control found in bacteria?

Accepted Answer

A)  control of chromatin remodeling 
B)  control of RNA splicing 
C)  transcriptional control 
D)  control of both RNA splicing and chromatin remodeling 
A)  control of chromatin remodeling 
B)  control of RNA splicing 
C)  transcriptional control 
D)  control of both RNA splicing and chromatin remodeling

Exam 18: Regulation of Gene Expression

Most repressor proteins are allosteric. Which of the following molecules binds with the repressor to alter its conformation and therefore affect its function?

Which of the following conditions is most likely to cause the lactose operon to be transcribed?

Which of the following statements best describes the characteristics of siRNA?

Which of the following methods is utilized by eukaryotes to control their gene expression that is different from the type of control found in bacteria?

Evolution, the Themes of Biology, and Scientific Inquiry

The Chemical Context of Life

Water and Life

Carbon and the Molecular Diversity of Life

The Structure and Function of Large Biological Molecules

A Tour of the Cell

Membrane Structure and Function

An Introduction to Metabolism

Cellular Respiration and Fermentation

Photosynthesis

Cell Communication

The Cell Cycle

Meiosis and Sexual Life Cycles

Mendel and the Gene Idea

The Chromosomal Basis of Inheritance

The Molecular Basis of Inheritance

Gene Expression: From Gene to Protein

Viruses

DNA Tools and Biotechnology

Genomes and Their Evolution

Descent with Modification: A Darwinian View of Life

The Evolution of Populations

The Origin of Species

The History of Life on Earth

Phylogeny and the Tree of Life

Bacteria and Archaea

Protists

Plant Diversity I: How Plants Colonized Land

Plant Diversity II: The Evolution of Seed Plants

Fungi

An Overview of Animal Diversity

An Introduction to Invertebrates

The Origin and Evolution of Vertebrates

Vascular Plant Structure, Growth, and Development

Resource Acquisition and Transport in Vascular Plants

Soil and Plant Nutrition

Angiosperm Reproduction and Biotechnology

Plant Responses to Internal and External Signals

Basic Principles of Animal Form and Function

Animal Nutrition

Circulation and Gas Exchange

The Immune System

Osmoregulation and Excretion

Hormones and the Endocrine System

Animal Reproduction

Animal Development

Neurons, Synapses, and Signaling

Nervous Systems

Sensory and Motor Mechanisms

Animal Behavior

An Introduction to Ecology and the Biosphere

Population Ecology

Community Ecology

Ecosystems and Restoration Ecology

Conservation Biology and Global Change

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