Exam 18: Regulation of Gene Expression

The bicoid gene product is normally localized to the anterior end of the embryo. If large amounts of the product were injected into the posterior end as well, which of the following developmental events would occur?

Forms of the Ras protein found in tumors usually cause which of the following events to occur?

Which of the following statements about the DNA in one of your brain cells is true?

The cAMP receptor protein (CRP)is said to be responsible for positive regulation of the lac operon because ________.

Which of the following are maternal effect genes that control the orientation of the egg and thus the Drosophila embryo?

Cell differentiation always involves

Which of the following processes do normal proto-oncogenes typically exhibit?

Mutations in which of the following genes lead to transformations in the identity of entire body parts?

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. If a researcher moves the repressor gene (lacI), along with its promoter, to a position at some several thousand base pairs away from its normal position, which of the following results would be expected?

If a particular operon encodes enzymes for making an essential amino acid and is regulated like the trp operon, then

A genetic test to detect predisposition to cancer would likely examine the APC gene for involvement in which type(s)of cancer?

A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. Some time later, she finds that the introduced strand separates into single-stranded RNAs, one of which is degraded. What does this enable the remaining strand to do?

Among the newly discovered small noncoding RNAs, one type helps to reestablish ethylation patterns during gamete formation and blocks expression of some transposons. Which of the following types of RNA is responsible for this function?

Which axis in the embryo does the protein product of the bicoid gene in Drosophila determine?

In positive control of several sugar metabolism-related operons, the cAMP receptor protein (CRP)binds to DNA to stimulate transcription. Which of the following environmental conditions causes an increase in CRP activity in stimulating transcription?

Imagine that you've isolated a yeast mutant that contains histones resistant to acetylation. What phenotype would you predict for this mutant?

A researcher introduces double-stranded RNA into a culture of mammalian cells and can identify its location or that of its smaller subsections experimentally, using a fluorescent probe. When she finds that the introduced strand separates into single-stranded RNAs, what other evidence of this single-stranded RNA piece's activity would she find?

What would be the result of a mutation in a maternal effect gene in a female Drosophila?

According to the lac operon model proposed by Jacob and Monod, what is predicted to occur if the operator is removed from the operon?

How do steroid hormones produce their effects in cells?