Question 1

If a particular immunoglobulin heavy chain has 50 V genes, 27 D genes, and 6 J genes, how many different V(J)D combinations can be obtained?

Accepted Answer

A)  162 
B)  300 
C)  1350 
D)  8100 
A)  162 
B)  300 
C)  1350 
D)  8100

Question 2

Which of the following statements is true of T cells?

Accepted Answer

A)  T cells can directly interact with antigens without the involvement of MHC molecules. 
B)  T cells are nonspecific, and they recognize all antigens. 
C)  Each T-cell receptor is specific to a single antigen. 
D)  T cells can increase their diversity by somatic mutation. 
A)  T cells can directly interact with antigens without the involvement of MHC molecules. 
B)  T cells are nonspecific, and they recognize all antigens. 
C)  Each T-cell receptor is specific to a single antigen. 
D)  T cells can increase their diversity by somatic mutation.

Question 3

Which of the following cells produce antibodies?

Accepted Answer

A)  Memory cells 
B)  NK cells 
C)  Plasma cells 
D)  T cells 
A)  Memory cells 
B)  NK cells 
C)  Plasma cells 
D)  T cells

Question 4

Identify a protein that turns a naïve T cell into a regulatory T cell.

Accepted Answer

A)  CD 25 
B)  IL-2 
C)  Foxp3 
D)  CD 28 
A)  CD 25 
B)  IL-2 
C)  Foxp3 
D)  CD 28

Question 5

Which of the following diseases have been largely eradicated by the use of vaccines?

Accepted Answer

A)  rubella 
B)  polio 
C)  smallpox 
D)  All of these have been largely eradicated through the use of vaccines. 
E)  None of these have been largely eradicated through the use of vaccines. 
A)  rubella 
B)  polio 
C)  smallpox 
D)  All of these have been largely eradicated through the use of vaccines. 
E)  None of these have been largely eradicated through the use of vaccines.

Question 6

Which of the following molecules help lymphocytes enter the blood?

Accepted Answer

A)  chaperones 
B)  cytokines 
C)  lymphokines 
D)  transporters 
A)  chaperones 
B)  cytokines 
C)  lymphokines 
D)  transporters

Question 7

Which of the following is not an autoimmune disease?

Accepted Answer

A)  AIDS 
B)  Multiple sclerosis 
C)  Myasthenia gravis 
D)  None, they are all autoimmune diseases. 
A)  AIDS 
B)  Multiple sclerosis 
C)  Myasthenia gravis 
D)  None, they are all autoimmune diseases.

Question 8

Which of the following is not a problem associated with the use of antibiotics?

Accepted Answer

A)  Overuse can lead to the development of antibiotic-resistant strains of bacteria. 
B)  Patients often develop allergies on the subsequent use of a particular antibiotic. 
C)  Patients tend to use antibiotics indiscriminately. 
D)  None, these are all problems associated with the use of antibiotics. 
A)  Overuse can lead to the development of antibiotic-resistant strains of bacteria. 
B)  Patients often develop allergies on the subsequent use of a particular antibiotic. 
C)  Patients tend to use antibiotics indiscriminately. 
D)  None, these are all problems associated with the use of antibiotics.

Question 9

Which of the following immune system components bring characteristic portions of antigens to cell surfaces?

Accepted Answer

A)  Antibodies 
B)  B cells 
C)  MHC molecules 
D)  T cells 
A)  Antibodies 
B)  B cells 
C)  MHC molecules 
D)  T cells

Question 10

Which of the following cells have both activating and inhibitory receptors?

Accepted Answer

A)  B cells 
B)  Macrophages 
C)  T cells 
D)  All of these 
A)  B cells 
B)  Macrophages 
C)  T cells 
D)  All of these

Question 11

Identify a monoclonal antibody that inhibits the action of the HER2 protein in breast cancer.

Accepted Answer

A)  cetuximab 
B)  naproxen 
C)  ibuprofen 
D)  trastuzumab 
A)  cetuximab 
B)  naproxen 
C)  ibuprofen 
D)  trastuzumab

Question 12

How does HER2 influence breast cancer development?

Accepted Answer

A)  It suppresses the activity of oncogenes. 
B)  It causes aggressive tumor growth. 
C)  It prevents the metastasis of cancer cells. 
D)  It promotes the localization of a cancerous tumor. 
A)  It suppresses the activity of oncogenes. 
B)  It causes aggressive tumor growth. 
C)  It prevents the metastasis of cancer cells. 
D)  It promotes the localization of a cancerous tumor.

Question 13

Identify the immunoglobulins present in secretions such as tears and milk.

Accepted Answer

A)  IgE 
B)  IgA 
C)  IgG 
D)  IgM 
A)  IgE 
B)  IgA 
C)  IgG 
D)  IgM

Question 14

Which of the following statements is true of retrovaccination?

Accepted Answer

A)  It involves vaccinating a person who already has a disease. 
B)  It involves finding a vaccine that elicits an antibody. 
C)  It involves finding a vaccine against a specific antigen. 
D)  It involves finding vaccines that act only against retroviruses. 
A)  It involves vaccinating a person who already has a disease. 
B)  It involves finding a vaccine that elicits an antibody. 
C)  It involves finding a vaccine against a specific antigen. 
D)  It involves finding vaccines that act only against retroviruses.

Question 15

Which of the following characteristics of T-cell receptors makes them a member of the immunoglobulin superfamily?

Accepted Answer

A)  their lack of antigen specificity 
B)  the presence of constant and variable regions 
C)  their glycolipid structure 
D)  the ability to undergo somatic mutation 
A)  their lack of antigen specificity 
B)  the presence of constant and variable regions 
C)  their glycolipid structure 
D)  the ability to undergo somatic mutation

Question 16

Which of the following T cells are the primary targets of HIV?

Accepted Answer

A)  helper T cells 
B)  killer T cells 
C)  regulatory T cells 
D)  all of these 
A)  helper T cells 
B)  killer T cells 
C)  regulatory T cells 
D)  all of these

Question 17

Which of the following is a function of antiviral drugs for HIV?

Accepted Answer

A)  They inhibit the activity of proteases. 
B)  They inhibit the activity of reverse transcriptase. 
C)  They prevent the virus from entering the host's cells. 
D)  All of these are functions. 
A)  They inhibit the activity of proteases. 
B)  They inhibit the activity of reverse transcriptase. 
C)  They prevent the virus from entering the host's cells. 
D)  All of these are functions.

Question 18

Which of the following diseases is treated using the monoclonal antibody drug trastuzumab?

Accepted Answer

A)  breast cancer 
B)  prostate cancer 
C)  non-Hodgkin's lymphoma 
D)  none of these 
A)  breast cancer 
B)  prostate cancer 
C)  non-Hodgkin's lymphoma 
D)  none of these

Question 19

Which of the following diseases is diagnosed using monoclonal antibodies?

Accepted Answer

A)  AIDS 
B)  Breast cancer 
C)  Leukemia 
D)  None of these 
A)  AIDS 
B)  Breast cancer 
C)  Leukemia 
D)  None of these

Question 20

Which of the following is not a lymphoid organ?

Accepted Answer

A)  the spleen 
B)  the thymus 
C)  the tonsils 
D)  None, they are all lymphoid organs. 
A)  the spleen 
B)  the thymus 
C)  the tonsils 
D)  None, they are all lymphoid organs.

Exam 30: Immunochemistry

If a particular immunoglobulin heavy chain has 50 V genes, 27 D genes, and 6 J genes, how many different V(J)D combinations can be obtained?

Which of the following statements is true of T cells?

Which of the following cells produce antibodies?

Identify a protein that turns a naïve T cell into a regulatory T cell.

Which of the following diseases have been largely eradicated by the use of vaccines?

Which of the following molecules help lymphocytes enter the blood?

Which of the following is not an autoimmune disease?

Which of the following is not a problem associated with the use of antibiotics?

Which of the following immune system components bring characteristic portions of antigens to cell surfaces?

Which of the following cells have both activating and inhibitory receptors?

Identify a monoclonal antibody that inhibits the action of the HER2 protein in breast cancer.

How does HER2 influence breast cancer development?

Identify the immunoglobulins present in secretions such as tears and milk.

Which of the following statements is true of retrovaccination?

Which of the following characteristics of T-cell receptors makes them a member of the immunoglobulin superfamily?

Which of the following T cells are the primary targets of HIV?

Which of the following is a function of antiviral drugs for HIV?

Which of the following diseases is treated using the monoclonal antibody drug trastuzumab?

Which of the following diseases is diagnosed using monoclonal antibodies?

Which of the following is not a lymphoid organ?

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