Question 1

Which of the following processes occurs as a result of V(J)D gene mutations in somatic cells?

Accepted Answer

A)  affinity maturation 
B)  affinity mutation 
C)  cancer 
D)  none of these 
A)  affinity maturation 
B)  affinity mutation 
C)  cancer 
D)  none of these

Question 2

Which of the following is a drawback of highly active antiretroviral therapy (HAART)?

Accepted Answer

A)  It causes the destruction of stem cells in the bone marrow. 
B)  It enhances the ability of viral particles to fight the innate immunity of the body. 
C)  It fails to completely eradicate the viral particles from the body. 
D)  It reduces the immunity of the body. 
A)  It causes the destruction of stem cells in the bone marrow. 
B)  It enhances the ability of viral particles to fight the innate immunity of the body. 
C)  It fails to completely eradicate the viral particles from the body. 
D)  It reduces the immunity of the body.

Question 3

Which of the following statements is true of a situation where the body encounters the same invader twice?

Accepted Answer

A)  Both the first and second immune responses are slow. 
B)  The first response is faster than the second response. 
C)  The second response is faster than the first response. 
D)  Both the first and second immune responses are fast. 
A)  Both the first and second immune responses are slow. 
B)  The first response is faster than the second response. 
C)  The second response is faster than the first response. 
D)  Both the first and second immune responses are fast.

Question 4

When was the role of MHC molecules in the immune response first discovered?

Accepted Answer

A)  during the study of AIDS 
B)  during the study of blood types 
C)  during organ transplants 
D)  none of these 
A)  during the study of AIDS 
B)  during the study of blood types 
C)  during organ transplants 
D)  none of these

Question 5

Which of the following statements is true of the specificity of NK and Tc cells?

Accepted Answer

A)  Both of them are highly target specific. 
B)  Neither of them is target specific. 
C)  NK cells are nonspecific, but TC cells are specific. 
D)  NK cells are specific, but TC cells are nonspecific. 
A)  Both of them are highly target specific. 
B)  Neither of them is target specific. 
C)  NK cells are nonspecific, but TC cells are specific. 
D)  NK cells are specific, but TC cells are nonspecific.

Question 6

What is the full form of APC?

Accepted Answer

A)  antibody presenting cells 
B)  antibody processing cells 
C)  antigen presenting cells 
D)  antigen processing cells 
A)  antibody presenting cells 
B)  antibody processing cells 
C)  antigen presenting cells 
D)  antigen processing cells

Question 7

Which of the following antigens are affected by the enzyme GILT?

Accepted Answer

A)  nucleic acid antigens 
B)  polysaccharide antigens 
C)  peptide antigens 
D)  all of these 
A)  nucleic acid antigens 
B)  polysaccharide antigens 
C)  peptide antigens 
D)  all of these

Question 8

Which of the following chemical interactions hold the chains of a T-cell receptor together?

Accepted Answer

A)  disulfide bonds 
B)  hydrogen bonds 
C)  hydrophobic interactions 
D)  ionic bonds 
A)  disulfide bonds 
B)  hydrogen bonds 
C)  hydrophobic interactions 
D)  ionic bonds

Question 9

Identify a secondary signaling pathway that controls the proliferation of B cells.

Accepted Answer

A)  deactivation by tyrosine kinase 
B)  activation by phosphatase 
C)  both of these 
D)  neither of these 
A)  deactivation by tyrosine kinase 
B)  activation by phosphatase 
C)  both of these 
D)  neither of these

Question 10

Identify the components of the immune system that are associated with interferons.

Accepted Answer

A)  B cells 
B)  macrophages 
C)  NK cells 
D)  T cells 
A)  B cells 
B)  macrophages 
C)  NK cells 
D)  T cells

Question 11

Identify the cells that are produced after T cells interact with antigens.

Accepted Answer

A)  cytotoxic T cells 
B)  helper T cells 
C)  memory cells 
D)  all of these 
A)  cytotoxic T cells 
B)  helper T cells 
C)  memory cells 
D)  all of these

Question 12

Which of the following statements is true?

Accepted Answer

A)  B cells are lymphocytes, but T cells are not. 
B)  T cells are lymphocytes, but B cells are not. 
C)  Both B cells and T cells are lymphocytes. 
D)  Neither B cells nor T cells are lymphocytes. 
A)  B cells are lymphocytes, but T cells are not. 
B)  T cells are lymphocytes, but B cells are not. 
C)  Both B cells and T cells are lymphocytes. 
D)  Neither B cells nor T cells are lymphocytes.

Question 13

Which of the following antibodies recognizes sugars that are unique to HIV?

Accepted Answer

A)  b12 
B)  2G12 
C)  p7 
D)  p17 
A)  b12 
B)  2G12 
C)  p7 
D)  p17

Question 14

Which of the following immune system components belong to the immunoglobulin superfamily?

Accepted Answer

A)  Antibodies 
B)  T-cell receptors 
C)  MHC molecules 
D)  All of these 
A)  Antibodies 
B)  T-cell receptors 
C)  MHC molecules 
D)  All of these

Question 15

Which of the following statements is true of monoclonal antibodies?

Accepted Answer

A)  They are functionally identical, but structurally non-identical antibodies. 
B)  They fail to detect the presence of HIV in blood. 
C)  They can be used to assay for biomolecules that can act as antigens. 
D)  They are composed only of myeloma cells. 
A)  They are functionally identical, but structurally non-identical antibodies. 
B)  They fail to detect the presence of HIV in blood. 
C)  They can be used to assay for biomolecules that can act as antigens. 
D)  They are composed only of myeloma cells.

Question 16

Which of the following statements is true?

Accepted Answer

A)  Both B cells and T cells originate in the bone marrow. 
B)  Both B cells and T cells originate in the thymus. 
C)  Both B cells and T cells mature in the bone marrow. 
D)  Both B cells and T cells mature in the thymus. 
A)  Both B cells and T cells originate in the bone marrow. 
B)  Both B cells and T cells originate in the thymus. 
C)  Both B cells and T cells mature in the bone marrow. 
D)  Both B cells and T cells mature in the thymus.

Question 17

Which of the following bonds are found between CD3 molecules and TcRs in T-cell receptor complexes?

Accepted Answer

A)  covalent bonds 
B)  coordinate bonds 
C)  ionic bonds 
D)  intermolecular forces 
A)  covalent bonds 
B)  coordinate bonds 
C)  ionic bonds 
D)  intermolecular forces

Question 18

How do glucocorticoids regulate the synthesis of cytokines?

Accepted Answer

A)  by directly interacting with the genes for cytokines 
B)  by interacting with the transcription factors for cytokines 
C)  by both of these mechanisms 
D)  by neither of these mechanisms 
A)  by directly interacting with the genes for cytokines 
B)  by interacting with the transcription factors for cytokines 
C)  by both of these mechanisms 
D)  by neither of these mechanisms

Question 19

Which of the following enzymes surrounds the HIV genome?

Accepted Answer

A)  protease 
B)  virus-specific reverse transcriptase 
C)  both of these 
D)  neither of these 
A)  protease 
B)  virus-specific reverse transcriptase 
C)  both of these 
D)  neither of these

Question 20

How many different types of antibodies are produced by a B cell?

Accepted Answer

A)  one 
B)  two 
C)  five 
D)  ten 
A)  one 
B)  two 
C)  five 
D)  ten

Exam 30: Immunochemistry

Which of the following processes occurs as a result of V(J)D gene mutations in somatic cells?

Which of the following is a drawback of highly active antiretroviral therapy (HAART)?

Which of the following statements is true of a situation where the body encounters the same invader twice?

When was the role of MHC molecules in the immune response first discovered?

Which of the following statements is true of the specificity of NK and Tc cells?

What is the full form of APC?

Which of the following antigens are affected by the enzyme GILT?

Which of the following chemical interactions hold the chains of a T-cell receptor together?

Identify a secondary signaling pathway that controls the proliferation of B cells.

Identify the components of the immune system that are associated with interferons.

Identify the cells that are produced after T cells interact with antigens.

Which of the following statements is true?

Which of the following antibodies recognizes sugars that are unique to HIV?

Which of the following immune system components belong to the immunoglobulin superfamily?

Which of the following statements is true of monoclonal antibodies?

Which of the following statements is true?

Which of the following bonds are found between CD3 molecules and TcRs in T-cell receptor complexes?

How do glucocorticoids regulate the synthesis of cytokines?

Which of the following enzymes surrounds the HIV genome?

How many different types of antibodies are produced by a B cell?

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Which of the following statements is true of the specificity of NK and T_c cells?