Question 1

What is the primary treatment for the leukemias?

Accepted Answer

A)  Radiation 
B)  Chemotherapy 
C)  Surgery 
D)  Immunotherapy 
A)  Radiation 
B)  Chemotherapy 
C)  Surgery 
D)  Immunotherapy

Question 2

All of the following apply to vitamin K EXCEPT:

Accepted Answer

A)  it is used as an antidote for warfarin (Coumadin). 
B)  the liver requires it to produce prothrombin. 
C)  it is a fat-soluble vitamin. 
D)  the bone marrow requires it to synthesize hemoglobin. 
A)  it is used as an antidote for warfarin (Coumadin). 
B)  the liver requires it to produce prothrombin. 
C)  it is a fat-soluble vitamin. 
D)  the bone marrow requires it to synthesize hemoglobin.

Question 3

Why do abnormally low hemoglobin values develop with pernicious anemia?

Accepted Answer

A)  Decreased production of erythrocytes 
B)  Shorter life span of erythrocytes 
C)  Abnormal structure of hemoglobin chains 
D)  Deficit of folic acid 
A)  Decreased production of erythrocytes 
B)  Shorter life span of erythrocytes 
C)  Abnormal structure of hemoglobin chains 
D)  Deficit of folic acid

Question 4

In individuals with pernicious anemia, antibodies form to:

Accepted Answer

A)  vitamin B12. 
B)  intrinsic factor or parietal cells. 
C)  mucus-producing glands. 
D)  hydrochloric acid. 
A)  vitamin B12. 
B)  intrinsic factor or parietal cells. 
C)  mucus-producing glands. 
D)  hydrochloric acid.

Question 5

Multiple myeloma is a malignant tumor involving:

Accepted Answer

A)  plasma cells. 
B)  granulocytes. 
C)  bone cells. 
D)  lymph nodes. 
A)  plasma cells. 
B)  granulocytes. 
C)  bone cells. 
D)  lymph nodes.

Question 6

Why do vascular occlusions and infarcts occur frequently with sickle cell anemia?

Accepted Answer

A)  The red blood cells are abnormally large. 
B)  Increased hemolysis of erythrocytes occurs. 
C)  Erythrocytes change to sickle shape when hypoxia occurs. 
D)  HbS is unable to transport oxygen. 
A)  The red blood cells are abnormally large. 
B)  Increased hemolysis of erythrocytes occurs. 
C)  Erythrocytes change to sickle shape when hypoxia occurs. 
D)  HbS is unable to transport oxygen.

Question 7

Jaundice is one typical sign of:

Accepted Answer

A)  sickle cell anemia. 
B)  aplastic anemia. 
C)  iron deficiency anemia. 
D)  acute leukemia. 
A)  sickle cell anemia. 
B)  aplastic anemia. 
C)  iron deficiency anemia. 
D)  acute leukemia.

Question 8

What are the common early signs of aplastic anemia?

Accepted Answer

A)  Painful joints and skeletal deformity 
B)  Abdominal discomfort and splenomegaly 
C)  Excessive bleeding and recurrent infections 
D)  Palpitations and chest pain 
A)  Painful joints and skeletal deformity 
B)  Abdominal discomfort and splenomegaly 
C)  Excessive bleeding and recurrent infections 
D)  Palpitations and chest pain

Question 9

Microcytic and hypochromic erythrocytes are commonly found as a result of:

Accepted Answer

A)  iron deficiency anemia. 
B)  polycythemia. 
C)  disseminated intravascular coagulation. 
D)  hemophilia A. 
A)  iron deficiency anemia. 
B)  polycythemia. 
C)  disseminated intravascular coagulation. 
D)  hemophilia A.

Question 10

Which of the following applies to sickle cell trait?

Accepted Answer

A)  Most hemoglobin is in the form of HgS 
B)  Sickling of erythrocytes occurs with severe hypoxia. 
C)  Painful sickling crises with multiple infarctions occur frequently. 
D)  A child's skeletal growth is delayed. 
A)  Most hemoglobin is in the form of HgS 
B)  Sickling of erythrocytes occurs with severe hypoxia. 
C)  Painful sickling crises with multiple infarctions occur frequently. 
D)  A child's skeletal growth is delayed.

Question 11

Chronic blood loss causes anemia because of the:

Accepted Answer

A)  shortened life span of the erythrocytes. 
B)  lower metabolic rate. 
C)  loss of protein and electrolytes. 
D)  smaller amount of recycled iron available. 
A)  shortened life span of the erythrocytes. 
B)  lower metabolic rate. 
C)  loss of protein and electrolytes. 
D)  smaller amount of recycled iron available.

Question 12

Which of the following applies to the leukemias?

Accepted Answer

A)  Chronic leukemias are more common in older people. 
B)  AML is the most common childhood leukemia. 
C)  Exposure to chemicals is not considered a predisposing factor. 
D)  Lymphoid tissue produces abnormal leukocytes. 
A)  Chronic leukemias are more common in older people. 
B)  AML is the most common childhood leukemia. 
C)  Exposure to chemicals is not considered a predisposing factor. 
D)  Lymphoid tissue produces abnormal leukocytes.

Question 13

What term is used to describe a deficit of all types of blood cells?

Accepted Answer

A)  Leucopenia 
B)  Neutropenia 
C)  Pancytopenia 
D)  Erythrocytosis 
A)  Leucopenia 
B)  Neutropenia 
C)  Pancytopenia 
D)  Erythrocytosis

Question 14

Leukemia is sometimes linked to chromosome abnormalities, as evidenced by:

Accepted Answer

A)  the presence of Philadelphia chromosome translocation in cases of acute myelogenous leukemia (AML). 
B)  very low incidence in persons with Down syndrome. 
C)  little evidence of familial incidence. 
D)  transmission as a recessive gene. 
A)  the presence of Philadelphia chromosome translocation in cases of acute myelogenous leukemia (AML). 
B)  very low incidence in persons with Down syndrome. 
C)  little evidence of familial incidence. 
D)  transmission as a recessive gene.

Question 15

In individuals with acute leukemia, the increased number of malignant leukocytes leads to:
1) decreased hemoglobin.
2) thrombocytopenia.
3) bone pain with increased activity.
4) splenomegaly.

Accepted Answer

A) 1, 3 
B) 1, 2, 4 
C) 2, 3, 4 
D) 1, 2, 3, 4 
A) 1, 3 
B) 1, 2, 4 
C) 2, 3, 4 
D) 1, 2, 3, 4

Question 16

Which of the following can result from a malabsorption problem?

Accepted Answer

A)  Aplastic anemia 
B)  Sickle cell anemia 
C)  Thalassemia major 
D)  Pernicious anemia 
A)  Aplastic anemia 
B)  Sickle cell anemia 
C)  Thalassemia major 
D)  Pernicious anemia

Question 17

Which of the following statements applies to hemochromatosis. It is:

Accepted Answer

A)  caused by excessive iron intake in the diet. 
B)  results from excessive hemolysis of RBCs. 
C)  a metabolic error that leads to excess amounts of hemosiderin, causing damage to organs. 
D)  an inherited defect that results in abnormal hemoglobin. 
A)  caused by excessive iron intake in the diet. 
B)  results from excessive hemolysis of RBCs. 
C)  a metabolic error that leads to excess amounts of hemosiderin, causing damage to organs. 
D)  an inherited defect that results in abnormal hemoglobin.

Question 18

What is the cause of sickle cell anemia?

Accepted Answer

A)  A defective gene inherited from both parents 
B)  A chronic bacterial infection 
C)  Bone marrow depression 
D)  An autoimmune reaction 
A)  A defective gene inherited from both parents 
B)  A chronic bacterial infection 
C)  Bone marrow depression 
D)  An autoimmune reaction

Question 19

What are the typical early general signs and symptoms of anemia?

Accepted Answer

A)  Chest pain, palpitations 
B)  Jaundice, stomatitis 
C)  Pallor, dyspnea, and fatigue 
D)  Bradycardia, heat intolerance 
A)  Chest pain, palpitations 
B)  Jaundice, stomatitis 
C)  Pallor, dyspnea, and fatigue 
D)  Bradycardia, heat intolerance

Question 20

Which of the following diagnostic tests would be within the normal range for an individual with hemophilia A?

Accepted Answer

A)  Bleeding time 
B)  Coagulation time 
C)  PTT time 
D)  Prothrombin time 
A)  Bleeding time 
B)  Coagulation time 
C)  PTT time 
D)  Prothrombin time

Exam 10: Blood and Circulatory System Disorders

What is the primary treatment for the leukemias?

All of the following apply to vitamin K EXCEPT:

Why do abnormally low hemoglobin values develop with pernicious anemia?

In individuals with pernicious anemia, antibodies form to:

Multiple myeloma is a malignant tumor involving:

Why do vascular occlusions and infarcts occur frequently with sickle cell anemia?

Jaundice is one typical sign of:

What are the common early signs of aplastic anemia?

Microcytic and hypochromic erythrocytes are commonly found as a result of:

Which of the following applies to sickle cell trait?

Chronic blood loss causes anemia because of the:

Which of the following applies to the leukemias?

What term is used to describe a deficit of all types of blood cells?

Leukemia is sometimes linked to chromosome abnormalities, as evidenced by:

In individuals with acute leukemia, the increased number of malignant leukocytes leads to: 1) decreased hemoglobin. 2) thrombocytopenia. 3) bone pain with increased activity. 4) splenomegaly.

Which of the following can result from a malabsorption problem?

Which of the following statements applies to hemochromatosis. It is:

What is the cause of sickle cell anemia?

What are the typical early general signs and symptoms of anemia?

Which of the following diagnostic tests would be within the normal range for an individual with hemophilia A?

Introduction to Pathophysiology

Fluid, Electrolyte, and Acid-Base Imbalances

Introduction to Basic Pharmacology and Other Common Therapies

Pain

Inflammation and Healing

Infection

Immunity

Skin Disorders

Musculoskeletal Disorders

Lymphatic System Disorders

Cardiovascular System Disorders

Respiratory System Disorders

Neurological Disorders

Disorders of the Eye, Ear, and Other Sensory Organs

Endocrine System Disorders

Digestive System Disorders

Urinary System Disorders

Reproductive System Disorders

Neoplasms and Cancer

Congenital and Genetic Disorders

Complications Due to Pregnancy

Complications Due to Adolescence

Complications Due to Aging

Immobility and Associated Problems

Stress and Associated Problems

Substance Abuse and Associated Problems

Environmental Hazards and Associated Problems

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