Question 1

Platelet aggregation is dependent on the presence of:

Accepted Answer

A) Calcium ions 
B) Sodium citrate 
C) Magnesium 
D) Potassium 
A) Calcium ions 
B) Sodium citrate 
C) Magnesium 
D) Potassium A

Question 2

Which organ is responsible for sheltering 20% of the total platelet volume in the circulation?

Accepted Answer

A) Kidneys 
B) Adrenal gland 
C) Spleen 
D) Liver 
A) Kidneys 
B) Adrenal gland 
C) Spleen 
D) Liver C

Question 3

Tissue factor pathway inhibitor (TFPI):

Accepted Answer

A) Prevents activation of factor X by VIIa 
B) Activates the common pathway 
C) Inhibits fibrinolysis 
D) Inhibits the kallikrein proteins 
A) Prevents activation of factor X by VIIa 
B) Activates the common pathway 
C) Inhibits fibrinolysis 
D) Inhibits the kallikrein proteins A

Question 4

Which of the following proteins is not made in the liver?

Accepted Answer

A) Anti-hemophiliac factor 
B) Prothrombin 
C) Fibrinogen 
D) von Willebrand factor 
A) Anti-hemophiliac factor 
B) Prothrombin 
C) Fibrinogen 
D) von Willebrand factor

Question 5

In the prothrombin test, the patient's citrated plasma is combined with:

Accepted Answer

A) Phospholipids 
B) Thromboplastin only 
C) Ca2+ and actin 
D) Ca2+ and thromboplastin 
A) Phospholipids 
B) Thromboplastin only 
C) Ca2+ and actin 
D) Ca2+ and thromboplastin

Question 6

The vasoconstrictor substance released from the platelets at the site of injury is:

Accepted Answer

A) Thrombin 
B) Thromboxane A2 
C) Adenosine diphosphate 
D) Prostacyclin 
A) Thrombin 
B) Thromboxane A2 
C) Adenosine diphosphate 
D) Prostacyclin

Question 7

The main substrate of the coagulation system is:

Accepted Answer

A) Calcium 
B) ADP 
C) Collagen 
D) Fibrinogen 
A) Calcium 
B) ADP 
C) Collagen 
D) Fibrinogen

Question 8

The two inhibitors that keep the activation of coagulation under control are:

Accepted Answer

A) TFPI and thrombomodulin 
B) Protein C and protein S 
C) Protease inhibitors and the protein C pathway 
D) Alpha 2 macroglobulin and alpha 1 antitrypsin 
A) TFPI and thrombomodulin 
B) Protein C and protein S 
C) Protease inhibitors and the protein C pathway 
D) Alpha 2 macroglobulin and alpha 1 antitrypsin

Question 9

Which factor is measured by both the PT and the aPTT?

Accepted Answer

A) VIII 
B) IX 
C) V 
D) XIII 
A) VIII 
B) IX 
C) V 
D) XIII

Question 10

The average life span of a platelet in a normal adult is:

Accepted Answer

A) 1 to 5 days 
B) 5 to 7 days 
C) 7 to 10 days 
D) 18 to 21 days 
A) 1 to 5 days 
B) 5 to 7 days 
C) 7 to 10 days 
D) 18 to 21 days

Question 11

Which of the following is not a component of the fibrinolytic system?

Accepted Answer

A) Thrombin 
B) Plasmin 
C) Tissue-type plasminogen activator (tP
A)  
D) Urokinase 
A) Thrombin 
B) Plasmin 
C) Tissue-type plasminogen activator (tP
A)  
D) Urokinase

Question 12

Factor II is also known as which of the following?

Accepted Answer

A) Thrombin 
B) Fibrinogen 
C) Prothrombin 
D) Fibrin 
A) Thrombin 
B) Fibrinogen 
C) Prothrombin 
D) Fibrin

Question 13

Platelets are synthesized in the:

Accepted Answer

A) Liver 
B) Spleen 
C) Lymph glands 
D) Bone marrow 
A) Liver 
B) Spleen 
C) Lymph glands 
D) Bone marrow

Question 14

The prothrombin group of factors consists of factors:

Accepted Answer

A) I, V, VIII, and XIII 
B) XI, XII, prekallikrein, and HMWK 
C) II, VII, IX, and X 
D) III, VIII, IX, and X 
A) I, V, VIII, and XIII 
B) XI, XII, prekallikrein, and HMWK 
C) II, VII, IX, and X 
D) III, VIII, IX, and X

Question 15

A decreased platelet count is most often anticipated when a patient demonstrates:

Accepted Answer

A) Thrombosis 
B) Petechiae 
C) Hemarthrosis 
D) Glossitis 
A) Thrombosis 
B) Petechiae 
C) Hemarthrosis 
D) Glossitis

Question 16

Which factor is involved in contact activation?

Accepted Answer

A) Factor X 
B) Fibrinogen 
C) Fitzgerald factor 
D) Factor II 
A) Factor X 
B) Fibrinogen 
C) Fitzgerald factor 
D) Factor II

Question 17

The first response of a cut vessel is:

Accepted Answer

A) Vasoconstriction 
B) Platelet aggregation 
C) Activation of the intrinsic pathway 
D) Vasodilation 
A) Vasoconstriction 
B) Platelet aggregation 
C) Activation of the intrinsic pathway 
D) Vasodilation

Question 18

The anticoagulant known as heparin:

Accepted Answer

A) Inhibits PF3 activity 
B) Inhibits thrombin activity 
C) Degrades antithrombin activity 
D) Chelates calcium 
A) Inhibits PF3 activity 
B) Inhibits thrombin activity 
C) Degrades antithrombin activity 
D) Chelates calcium

Platelet aggregation is dependent on the presence of:

Which organ is responsible for sheltering 20% of the total platelet volume in the circulation?

Tissue factor pathway inhibitor (TFPI):

Which of the following proteins is not made in the liver?

In the prothrombin test, the patient's citrated plasma is combined with:

The vasoconstrictor substance released from the platelets at the site of injury is:

The main substrate of the coagulation system is:

The two inhibitors that keep the activation of coagulation under control are:

Which factor is measured by both the PT and the aPTT?

The average life span of a platelet in a normal adult is:

Which of the following is not a component of the fibrinolytic system?

Factor II is also known as which of the following?

Platelets are synthesized in the:

The prothrombin group of factors consists of factors:

A decreased platelet count is most often anticipated when a patient demonstrates:

Which factor is involved in contact activation?

The first response of a cut vessel is:

The anticoagulant known as heparin:

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Quantitative and Qualitative Platelet Disorders

Defects of Plasma Clotting Factors

Fibrinogen, Thrombin, and the Fibrinolytic System

Introduction to Thrombosis and Anticoagulant Therapy

Hematology Automation and Flow Cell Cytometry

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Exam 15: Overview of Hemostasis and Platelet Physiology

Platelet aggregation is dependent on the presence of:

Which organ is responsible for sheltering 20% of the total platelet volume in the circulation?

Tissue factor pathway inhibitor (TFPI):

Which of the following proteins is not made in the liver?

In the prothrombin test, the patient's citrated plasma is combined with:

The vasoconstrictor substance released from the platelets at the site of injury is:

The main substrate of the coagulation system is:

The two inhibitors that keep the activation of coagulation under control are:

Which factor is measured by both the PT and the aPTT?

The average life span of a platelet in a normal adult is:

Which of the following is not a component of the fibrinolytic system?

Factor II is also known as which of the following?

Platelets are synthesized in the:

The prothrombin group of factors consists of factors:

A decreased platelet count is most often anticipated when a patient demonstrates:

Which factor is involved in contact activation?

The first response of a cut vessel is:

The anticoagulant known as heparin:

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Quantitative and Qualitative Platelet Disorders

Defects of Plasma Clotting Factors

Fibrinogen, Thrombin, and the Fibrinolytic System

Introduction to Thrombosis and Anticoagulant Therapy

Hematology Automation and Flow Cell Cytometry

Filters