Question 1

Which of the following PT results would most likely be seen in a patient who is on Coumadin and is stable?

Accepted Answer

A) Approximately 26 seconds 
B) Approximately 13 seconds 
C) Approximately 40 seconds 
D) Approximately 60 seconds 
A) Approximately 26 seconds 
B) Approximately 13 seconds 
C) Approximately 40 seconds 
D) Approximately 60 seconds A

Question 2

Arterial thrombosis is associated with:

Accepted Answer

A) Antithrombin deficiency 
B) Protein S deficiency 
C) Protein C deficiency 
D) Both protein S and C deficiencies 
A) Antithrombin deficiency 
B) Protein S deficiency 
C) Protein C deficiency 
D) Both protein S and C deficiencies D

Question 3

Factor Xa inhibitors are monitored using which assay?

Accepted Answer

A) APTT 
B) PT 
C) anti-factor Xa assay 
D) platelet count 
A) APTT 
B) PT 
C) anti-factor Xa assay 
D) platelet count C

Question 4

The international normalized ratio (INR) is useful in:

Accepted Answer

A) The detection of coagulation factor deficiencies 
B) Monitoring heparin therapy 
C) The detection of inhibitors 
D) Monitoring Coumadin therapy 
A) The detection of coagulation factor deficiencies 
B) Monitoring heparin therapy 
C) The detection of inhibitors 
D) Monitoring Coumadin therapy

Question 5

Which test should be ordered as a baseline before started heparin therapy on a patient?

Accepted Answer

A) PT 
B) Platelet count 
C) APTT 
D) Fibrinogen 
A) PT 
B) Platelet count 
C) APTT 
D) Fibrinogen

Question 6

All of the following statements are true regarding Coumadin except:

Accepted Answer

A) It is a vitamin K antagonist. 
B) It needs antithrombin as a cofactor. 
C) PT is used to monitor its dosage. 
D) It is not recommended for pregnant and lactating women. 
A) It is a vitamin K antagonist. 
B) It needs antithrombin as a cofactor. 
C) PT is used to monitor its dosage. 
D) It is not recommended for pregnant and lactating women.

Question 7

Protein C is activated by which of the following?

Accepted Answer

A) Heparin cofactor II 
B) Factor VIIIa 
C) Antithrombin 
D) Protein S 
A) Heparin cofactor II 
B) Factor VIIIa 
C) Antithrombin 
D) Protein S

Question 8

All of the following can cause thrombosis except:

Accepted Answer

A) Low platelet count 
B) Activation of coagulation systems 
C) Vascular injury 
D) Deficiencies of coagulation inhibitors 
A) Low platelet count 
B) Activation of coagulation systems 
C) Vascular injury 
D) Deficiencies of coagulation inhibitors

Question 9

The target therapeutic range for an INR in patients with thromboembolic disease is:

Accepted Answer

A) 1 to 2 
B) 1.5 to 2.5 
C) 2 to 3 
D) 2 to 2.5 
A) 1 to 2 
B) 1.5 to 2.5 
C) 2 to 3 
D) 2 to 2.5

Question 10

All of the following statements describe factor V Leiden except:

Accepted Answer

A) It is a cause of activated protein C resistance. 
B) It is associated with thrombocytopenia. 
C) It is associated with increased risk of thrombosis. 
D) Is an inherited disorder. 
A) It is a cause of activated protein C resistance. 
B) It is associated with thrombocytopenia. 
C) It is associated with increased risk of thrombosis. 
D) Is an inherited disorder.

Question 11

All of the following are naturally occurring thrombin inhibitors except:

Accepted Answer

A) AT 
B) Prothrombin cofactor II 
C) Protein C 
D) Plasmin 
A) AT 
B) Prothrombin cofactor II 
C) Protein C 
D) Plasmin

Question 12

Antithrombin inhibits all of the following factors except:

Accepted Answer

A) IIa 
B) VIIa 
C) IXa 
D) XIa 
A) IIa 
B) VIIa 
C) IXa 
D) XIa

Question 13

Heparin therapy is monitored best by performing routine:

Accepted Answer

A) PT/INRs 
B) Anti-factor Xa 
C) Fibrinogen levels 
D) Bleeding time tests 
A) PT/INRs 
B) Anti-factor Xa 
C) Fibrinogen levels 
D) Bleeding time tests

Question 14

The most common tests used to detect lupus anticoagulants include all of the following except:

Accepted Answer

A) aPTT 
B) Kaolin clotting time 
C) PT/INR 
D) Dilute Russell viper venom test 
A) aPTT 
B) Kaolin clotting time 
C) PT/INR 
D) Dilute Russell viper venom test

Question 15

Coumadin acts in such a way that it:

Accepted Answer

A) Alters the synthesis of vitamin K-dependent factors 
B) Reduces the circulating level of factors III and V 
C) Reduces the circulating level of factor I 
D) Cleaves carboxyreductase to generate glutamic acid 
A) Alters the synthesis of vitamin K-dependent factors 
B) Reduces the circulating level of factors III and V 
C) Reduces the circulating level of factor I 
D) Cleaves carboxyreductase to generate glutamic acid

Question 16

The lupus anticoagulant is directed against:

Accepted Answer

A) Factor VIII 
B) Factor X 
C) Factor IX 
D) Phospholipids 
A) Factor VIII 
B) Factor X 
C) Factor IX 
D) Phospholipids

Question 17

Heparin-induced thrombocytopenia (HIT) usually:

Accepted Answer

A) Occurs as a result of protein C deficiency 
B) Will show an increase in platelets 
C) Occurs 5 to 14 days after heparin therapy 
D) Occurs only in males 
A) Occurs as a result of protein C deficiency 
B) Will show an increase in platelets 
C) Occurs 5 to 14 days after heparin therapy 
D) Occurs only in males

Question 18

What is the term for the condition that predisposes patients to thrombosis?

Accepted Answer

A) Thrombopenia 
B) Thrombophilia 
C) Thrombocytosis 
D) Anemia 
A) Thrombopenia 
B) Thrombophilia 
C) Thrombocytosis 
D) Anemia

Question 19

Heparin:

Accepted Answer

A) Inhibits PF3 
B) Inhibits thrombin 
C) Degrades antithrombin 
D) Forms a complex with protein C 
A) Inhibits PF3 
B) Inhibits thrombin 
C) Degrades antithrombin 
D) Forms a complex with protein C

Question 20

Drug alternatives for patients with heparin-induced thrombocytopenia include:

Accepted Answer

A) Danaparoid 
B) Warfarin 
C) Streptokinase 
D) Aspirin 
A) Danaparoid 
B) Warfarin 
C) Streptokinase 
D) Aspirin

Which of the following PT results would most likely be seen in a patient who is on Coumadin and is stable?

Arterial thrombosis is associated with:

Factor Xa inhibitors are monitored using which assay?

The international normalized ratio (INR) is useful in:

Which test should be ordered as a baseline before started heparin therapy on a patient?

All of the following statements are true regarding Coumadin except:

Protein C is activated by which of the following?

All of the following can cause thrombosis except:

The target therapeutic range for an INR in patients with thromboembolic disease is:

All of the following statements describe factor V Leiden except:

All of the following are naturally occurring thrombin inhibitors except:

Antithrombin inhibits all of the following factors except:

Heparin therapy is monitored best by performing routine:

The most common tests used to detect lupus anticoagulants include all of the following except:

Coumadin acts in such a way that it:

The lupus anticoagulant is directed against:

Heparin-induced thrombocytopenia (HIT) usually:

What is the term for the condition that predisposes patients to thrombosis?

Heparin:

Drug alternatives for patients with heparin-induced thrombocytopenia include:

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Overview of Hemostasis and Platelet Physiology

Quantitative and Qualitative Platelet Disorders

Defects of Plasma Clotting Factors

Fibrinogen, Thrombin, and the Fibrinolytic System

Hematology Automation and Flow Cell Cytometry

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Exam 19: Introduction to Thrombosis and Anticoagulant Therapy

Which of the following PT results would most likely be seen in a patient who is on Coumadin and is stable?

Arterial thrombosis is associated with:

Factor Xa inhibitors are monitored using which assay?

The international normalized ratio (INR) is useful in:

Which test should be ordered as a baseline before started heparin therapy on a patient?

All of the following statements are true regarding Coumadin except:

Protein C is activated by which of the following?

All of the following can cause thrombosis except:

The target therapeutic range for an INR in patients with thromboembolic disease is:

All of the following statements describe factor V Leiden except:

All of the following are naturally occurring thrombin inhibitors except:

Antithrombin inhibits all of the following factors except:

Heparin therapy is monitored best by performing routine:

The most common tests used to detect lupus anticoagulants include all of the following except:

Coumadin acts in such a way that it:

The lupus anticoagulant is directed against:

Heparin-induced thrombocytopenia (HIT) usually:

What is the term for the condition that predisposes patients to thrombosis?

Heparin:

Drug alternatives for patients with heparin-induced thrombocytopenia include:

Introduction to Hematology and Basic Laboratory Practice

From Hematopoiesis to the Complete Blood Count

Blood Cell Production and Function and Relevant Red Cell Morphology

Hemoglobin Function and Principles of Hemolysis

The Microcytic Anemias

The Macrocytic Anemias

Normochromic Anemias: Biochemical and Membrane Disorders and Miscellaneous Red Cell Disorders

The Normochromic Anemias Due to Hemoglobinopathies

Leukopoiesis and Leukopoietic Function

Abnormalities of White Cells: Quantitative, Qualitative, and the Lipid Storage Diseases

Acute Leukemias

Myeloproliferative Neoplasms

Lymphoproliferative Disorders and Related Plasma Cell Disorders

The Myelodysplastic Syndromes

Overview of Hemostasis and Platelet Physiology

Quantitative and Qualitative Platelet Disorders

Defects of Plasma Clotting Factors

Fibrinogen, Thrombin, and the Fibrinolytic System

Hematology Automation and Flow Cell Cytometry

Filters