Question 1

Which is the most acidic hydrogen in the compound shown?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 2

Which is the most acidic hydrogen in the compound shown?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 3

Compounds having two carbonyl groups separated by a carbon atom are called ___.

Accepted Answer

@#LAT-DLM&-dicarbony

Question 4

The $\alpha$-hydrogens on carbonyl carbons are unusually acidic (pKa 19-20)because: ___.

Accepted Answer

the corresponding an

Question 5

Which of the following is a keto-enol tautomeric pair?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 6

Which compound would be formed when 2-methylbutanal is treated with a solution of NaOT in T2O?

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 7

The conversion of   is accomplished by the use of which oxidizing agent?

Accepted Answer

A) Ag(NH3)2+ 
B) O3 
C) NaOBr (Br2 in NaOH) 
D)    
E) Cu2+ 
A) Ag(NH3)2+ 
B) O3 
C) NaOBr (Br2 in NaOH) 
D)    
E) Cu2+

Question 8

Which is the most acidic hydrogen in the compound shown?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 9

What would be the major product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 10

Which compound would be formed when 2-methylbutanal is treated with a solution of D+ in D2O?

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 11

Considering only the highlighted hydrogens,list the following compounds in order of decreasing acidity:

Accepted Answer

A) I,II,III,IV,V 
B) II,V,III,I,IV 
C) IV,I,III,II,V 
D) IV,V,II,I,III 
E) V,IV,III,II,I 
A) I,II,III,IV,V 
B) II,V,III,I,IV 
C) IV,I,III,II,V 
D) IV,V,II,I,III 
E) V,IV,III,II,I

Question 12

What would be the major product of the following reaction?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 13

What is the final product of the following reaction sequence? Give structural details of all significant intermediates.

Accepted Answer

The answer of What is the final product of the...

Question 14

What synthetic strategy would accomplish the following transformation?

Accepted Answer

A) i)Br2,H3O+; ii)NaOC2H5,C2H5OH,heat 
B) i)Cl2,FeCl3; ii)NaOC2H5,C2H5OH,heat 
C) i)HCN; ii)H3O+,heat 
D) i)Br2,h$v$; ii)(CH3)3COK,(CH3)3COH,heat 
E) None of these choices. 
A) i)Br2,H3O+; ii)NaOC2H5,C2H5OH,heat 
B) i)Cl2,FeCl3; ii)NaOC2H5,C2H5OH,heat 
C) i)HCN; ii)H3O+,heat 
D) i)Br2,h$v$; ii)(CH3)3COK,(CH3)3COH,heat 
E) None of these choices.

Question 15

Which of the following represent keto-enol tautomers?

Accepted Answer

A)    
B)    
C)    
D) More than one of these choices. 
E) None of these choices. 
A)    
B)    
C)    
D) More than one of these choices. 
E) None of these choices.

Question 16

Which of these compounds would exist primarily in an enol form?

Accepted Answer

A)    
B)    
C)    
D)    
E)    
A)    
B)    
C)    
D)    
E)

Question 17

What product is finally formed when the initial compound formed from cyclohexanone and morpholine is mixed with methyl iodide and that product is heated and then hydrolyzed?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Question 18

Diastereomers that differ in configuration at only one stereogenic center are sometimes called ___,and their interconversion is called ___.

Accepted Answer

epimers; e

Question 19

Which reagent would best serve as the basis for a simple chemical test to distinguish between

Accepted Answer

A) NaOI (I2 in NaOH) 
B) Br2/CCl4 
C) CrO3/H2SO4 
D) NaHCO3/H2O 
E) Ag(NH3)2+ 
A) NaOI (I2 in NaOH) 
B) Br2/CCl4 
C) CrO3/H2SO4 
D) NaHCO3/H2O 
E) Ag(NH3)2+

Question 20

What would be the major product of the following reaction sequence?

Accepted Answer

A) I 
B) II 
C) III 
D) IV 
E) V 
A) I 
B) II 
C) III 
D) IV 
E) V

Exam 18: Reactions at the Α Carbon of Carbonyl Compounds

Which is the most acidic hydrogen in the compound shown?

Which is the most acidic hydrogen in the compound shown?

Compounds having two carbonyl groups separated by a carbon atom are called ___.

The α\alphaα -hydrogens on carbonyl carbons are unusually acidic (pKa 19-20)because: ___.

Which of the following is a keto-enol tautomeric pair?

Which compound would be formed when 2-methylbutanal is treated with a solution of NaOT in T2O?

The conversion of is accomplished by the use of which oxidizing agent?

Which is the most acidic hydrogen in the compound shown?

What would be the major product of the following reaction?

Which compound would be formed when 2-methylbutanal is treated with a solution of D+ in D2O?

Considering only the highlighted hydrogens,list the following compounds in order of decreasing acidity:

What would be the major product of the following reaction?

What is the final product of the following reaction sequence? Give structural details of all significant intermediates.

What synthetic strategy would accomplish the following transformation?

Which of the following represent keto-enol tautomers?

Which of these compounds would exist primarily in an enol form?

What product is finally formed when the initial compound formed from cyclohexanone and morpholine is mixed with methyl iodide and that product is heated and then hydrolyzed?

Diastereomers that differ in configuration at only one stereogenic center are sometimes called ___,and their interconversion is called ___.

Which reagent would best serve as the basis for a simple chemical test to distinguish between

What would be the major product of the following reaction sequence?

The Basics

Families of Carbon

Acids and Bases

Nomenclature and Conformations of Alkanes and Cycloalkanes

Stereochemistry

Nucleophilic Reactions

Alkenes and Alkynes I

Alkenes and Alkynes II

Nuclear Magnetic Resonance and Mass Spectrometry

Radical Reactions

Alcohols and Ethers

Alcohols From Carbonyl Compounds

Conjugated Unsaturated Systems

Aromatic Compounds

Reactions of Aromatic Compounds

Aldehydes and Ketones

Carboxylic Acids and Their Derivatives

Condensation and Conjugate Addition Reactions of Carbonyl Compounds

Amines

Transition Metal Complexes

Carbohydrates

Lipids

Amino Acids and Proteins

Nucleic Acids and Protein Synthesis

Filters

The $\alpha$ -hydrogens on carbonyl carbons are unusually acidic (pK_a 19-20)because: ___.

Which compound would be formed when 2-methylbutanal is treated with a solution of NaOT in T₂O?

Which compound would be formed when 2-methylbutanal is treated with a solution of D⁺ in D₂O?

Diastereomers that differ in configuration at only one stereogenic center are sometimes called _,and their interconversion is called _.