Exam 3: Protein Structure and Function

The following question(s) are based on the 15 molecules illustrated in the accompanying figure. Each molecule may be used once, more than once, or not at all. -Which type of interaction stabilizes the α-helix and the β-pleated sheet structures of proteins?

Which one of the following is NOT a component of each monomer used to make proteins?

In a normal cellular protein, where would you expect to find a hydrophobic amino acid like valine?

You disrupt all hydrogen bonds in a protein. What level of structure will be preserved?

When polymerization of a protein is complete, but a protein is still completely linear, what is the highest level of structure in the protein?

What type of covalent bond between amino acid side chains (R-groups) functions in maintaining a polypeptide's specific three-dimensional shape?

Refer to the following paragraph and accompanying figure to answer the following question(s). -If you were reading off the sequence of amino acids in the figure to a biologist friend, what should the first three letters be?

Identify the location of the disulfide bond in the figure, located at the bottom of the third transmembrane segment. What is the name of the amino acids that are forming this bond?

You determine the amino acid sequence of a protein and find it contains a long sequence of methionine, followed by a long sequence of proline, followed by a long sequence of valine. Using these data you predict the sequence of this protein's secondary structure will be ________.

A peptide bond ________.

Changing a single amino acid in a protein consisting of 325 amino acids would ________.

Which of the groups shown above is a functional group that helps stabilize proteins by forming covalent cross-links within or between protein molecules?

Suppose you discovered a new amino acid. Its R-group contains only hydrogen and carbon atoms. Predict the behavior of this amino acid.

Proteins in biological systems ________.

Why are polymerization reactions endergonic? Polymerization reactions ________.

Which molecule shown above contains an amino functional group but is NOT an amino acid?

The following questions are based on the 15 molecules illustrated in the accompanying figure. Each molecule may be used once, more than once, or not at all. Which of the following molecules act as building blocks (monomers) of polypeptides?

-The structure depicted the accompanying figure shows the ________.

Refer to the following paragraph and accompanying figure to answer the following question(s). -How many times does the protein in the figure cross the cell membrane?

In solution, why do hydrolysis reactions occur more readily than condensation reactions?