Question 1

Modafinil (Provigil) has been shown to be

Accepted Answer

A) equivalent to amphetamine in terms of its efficacy in the treatment of narcolepsy and abuse liability 
B) effective in the treatment of narcolepsy, without exhibiting any significant abuse liability 
C) effective in reducing nicotine dependence 
A) equivalent to amphetamine in terms of its efficacy in the treatment of narcolepsy and abuse liability 
B) effective in the treatment of narcolepsy, without exhibiting any significant abuse liability 
C) effective in reducing nicotine dependence

Question 2

Which of the following drugs has been shown in a variety of studies to successfully decrease the levels of cocaine craving in most cocaine dependent persons for at least two months?

Accepted Answer

A) methylphenidate (Ritalin) 
B) tricyclic antidepressants 
C) lithium 
D) none of these 
A) methylphenidate (Ritalin) 
B) tricyclic antidepressants 
C) lithium 
D) none of these

Question 3

Most of cocaine's reinforcing effects are believed to be due to its ability to inhibit the reuptake of

Accepted Answer

A) dopamine 
B) serotonin 
C) acetylcholine 
D) GABA 
A) dopamine 
B) serotonin 
C) acetylcholine 
D) GABA

Question 4

Why are cocaine and amphetamine commonly referred to as "stimulants" and under what conditions would this term not be appropriate for these drugs?

Accepted Answer

Because at low to moderate doses taken i

Question 5

One of caffeine's major mechanisms of action involves

Accepted Answer

A) stimulation of GABA receptors 
B) antagonism of adenosine at its receptors 
C) antagonism of catecholamine receptors 
D) all of these 
A) stimulation of GABA receptors 
B) antagonism of adenosine at its receptors 
C) antagonism of catecholamine receptors 
D) all of these

Question 6

For centuries South American Indians have been using cocaine without any obvious problems.This has been attributed to the Indians'

Accepted Answer

A) genetic tolerance to cocaine 
B) taking cocaine orally in small amounts 
C) chewing coca leaves which have a non-toxic form of cocaine in them 
D) using cocaine only at high altitudes 
A) genetic tolerance to cocaine 
B) taking cocaine orally in small amounts 
C) chewing coca leaves which have a non-toxic form of cocaine in them 
D) using cocaine only at high altitudes

Question 7

When given a chance to self-administer amphetamine, nonhumans will

Accepted Answer

A) generally not do so 
B) readily do so-often to the point of administering lethal dosages 
C) do so only if reinforced with food 
D) do so only if they are hungry 
A) generally not do so 
B) readily do so-often to the point of administering lethal dosages 
C) do so only if reinforced with food 
D) do so only if they are hungry

Question 8

Caffeine has been shown to significantly reduce alcohol's detrimental effects on

Accepted Answer

A) reaction time 
B) complex memory task performance 
C) driving skills 
D) all of these 
A) reaction time 
B) complex memory task performance 
C) driving skills 
D) all of these

Question 9

Which of the following pharmacodynamic actions is NOT found with acute administration of amphetamine?

Accepted Answer

A) enhanced release of monoamines from neurons 
B) inhibited reuptake of monoamines 
C) inhibition of monoamine oxidase (MAO) 
D) facilitation of Ca++ flow into neurons 
A) enhanced release of monoamines from neurons 
B) inhibited reuptake of monoamines 
C) inhibition of monoamine oxidase (MAO) 
D) facilitation of Ca++ flow into neurons

Question 10

Parkinson's disease has been attributed to ____________________________ dopamine in certain areas of the brain.

Accepted Answer

A) an excess of 
B) insufficient amounts of 
C) increased turnover of 
D) the metabolization of 
A) an excess of 
B) insufficient amounts of 
C) increased turnover of 
D) the metabolization of

Question 11

Low to moderate doses of amphetamine-related drugs generally

Accepted Answer

A) increase virtually all motor activities 
B) enhance performance on tasks requiring sustained attention 
C) enhance performance most dramatically when the person is fatigued 
D) only b and c 
A) increase virtually all motor activities 
B) enhance performance on tasks requiring sustained attention 
C) enhance performance most dramatically when the person is fatigued 
D) only b and c

Question 12

Continued exposure to high doses of amphetamine eventually results in

Accepted Answer

A) catecholamine depletion 
B) decreased extraneuronal metabolization 
C) increased catecholamine synthesis 
D) increased levels of monoamine oxidase 
A) catecholamine depletion 
B) decreased extraneuronal metabolization 
C) increased catecholamine synthesis 
D) increased levels of monoamine oxidase

Question 13

Tolerance development has been shown to occur for which of these psychostimulants?

Accepted Answer

A) caffeine 
B) amphetamine 
C) cocaine 
D) all of these 
A) caffeine 
B) amphetamine 
C) cocaine 
D) all of these

Question 14

The free-basing of cocaine is done to

Accepted Answer

A) achieve concentrations of cocaine in the brain very rapidly 
B) reduce the toxicity of cocaine 
C) reduce the side effects of cocaine 
D) all of these 
A) achieve concentrations of cocaine in the brain very rapidly 
B) reduce the toxicity of cocaine 
C) reduce the side effects of cocaine 
D) all of these

Question 15

What are some of the primary differences between cocaine and amphetamine?

Accepted Answer

The duration of cocaine's effects is sho

Question 16

In normal adult humans, alertness, decreased fatigue, improved ability to concentrate, and elevated mood are likely to be observed following administration of low doses of

Accepted Answer

A) amphetamine 
B) cocaine 
C) nicotine 
D) all of these 
A) amphetamine 
B) cocaine 
C) nicotine 
D) all of these

Question 17

Smoking "crack" cocaine is more likely to result in dependence than intranasal administration of cocaine because

Accepted Answer

A) crack has greater agonist activity in the brain 
B) crack enters the brain more rapidly and thus induces a more intense euphoric reaction 
C) the effects of crack last longer 
D) all of the above 
A) crack has greater agonist activity in the brain 
B) crack enters the brain more rapidly and thus induces a more intense euphoric reaction 
C) the effects of crack last longer 
D) all of the above

Question 18

Empirical evidence indicates that amphetamine's behavioral effects are

Accepted Answer

A) opposite in children and adults 
B) qualitatively similar in children and adults 
C) identical in children and adults 
D) opposite in normal children and those with attention deficit hyperactivity disorder 
A) opposite in children and adults 
B) qualitatively similar in children and adults 
C) identical in children and adults 
D) opposite in normal children and those with attention deficit hyperactivity disorder

Question 19

Cocaine and amphetamine differ most significantly in terms of their

Accepted Answer

A) duration of effects 
B) degree of absorption when administered orally 
C) local anesthetic action 
D) all of these 
A) duration of effects 
B) degree of absorption when administered orally 
C) local anesthetic action 
D) all of these

Question 20

Chronic use of cocaine can result in

Accepted Answer

A) tolerance development to many of its effects 
B) sensitization to its psychosis-inducing effects 
C) severe psychological dependence 
D) all of these 
A) tolerance development to many of its effects 
B) sensitization to its psychosis-inducing effects 
C) severe psychological dependence 
D) all of these

Modafinil (Provigil) has been shown to be

Which of the following drugs has been shown in a variety of studies to successfully decrease the levels of cocaine craving in most cocaine dependent persons for at least two months?

Most of cocaine's reinforcing effects are believed to be due to its ability to inhibit the reuptake of

Why are cocaine and amphetamine commonly referred to as "stimulants" and under what conditions would this term not be appropriate for these drugs?

One of caffeine's major mechanisms of action involves

For centuries South American Indians have been using cocaine without any obvious problems.This has been attributed to the Indians'

When given a chance to self-administer amphetamine, nonhumans will

Caffeine has been shown to significantly reduce alcohol's detrimental effects on

Which of the following pharmacodynamic actions is NOT found with acute administration of amphetamine?

Parkinson's disease has been attributed to ____________________________ dopamine in certain areas of the brain.

Low to moderate doses of amphetamine-related drugs generally

Continued exposure to high doses of amphetamine eventually results in

Tolerance development has been shown to occur for which of these psychostimulants?

The free-basing of cocaine is done to

What are some of the primary differences between cocaine and amphetamine?

In normal adult humans, alertness, decreased fatigue, improved ability to concentrate, and elevated mood are likely to be observed following administration of low doses of

Smoking "crack" cocaine is more likely to result in dependence than intranasal administration of cocaine because

Empirical evidence indicates that amphetamine's behavioral effects are

Cocaine and amphetamine differ most significantly in terms of their

Chronic use of cocaine can result in

Psychopharmacology in Perspective

Drug Classification and Behavioral Assessment

Basic Principles of Pharmacology

Excitability and Chemical Signaling in Nerve Cells

Synaptic Transmission, Drugs, and Chemical Neuroanatomy

Tolerance, Sensitization, Dependence, and Addiction

Antipsychotic Drugs and Neurochemical Hypotheses of Schizophrenia

Antidepressants and Mood Stabilizers

Sedative-Hypnotics, Anxiolytics, and Anticonvulsants

Drug Treatment of Cognitive Dysfunction

Naturally Occurring and Synthetic Opiates and Their Antagonists

Dissociative Anesthetics

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Exam 7: Psychomotor Stimulants and Antiparkinsonian Drugs

Modafinil (Provigil) has been shown to be

Which of the following drugs has been shown in a variety of studies to successfully decrease the levels of cocaine craving in most cocaine dependent persons for at least two months?

Most of cocaine's reinforcing effects are believed to be due to its ability to inhibit the reuptake of

Why are cocaine and amphetamine commonly referred to as "stimulants" and under what conditions would this term not be appropriate for these drugs?

One of caffeine's major mechanisms of action involves

For centuries South American Indians have been using cocaine without any obvious problems.This has been attributed to the Indians'

When given a chance to self-administer amphetamine, nonhumans will

Caffeine has been shown to significantly reduce alcohol's detrimental effects on

Which of the following pharmacodynamic actions is NOT found with acute administration of amphetamine?

Parkinson's disease has been attributed to ____________________________ dopamine in certain areas of the brain.

Low to moderate doses of amphetamine-related drugs generally

Continued exposure to high doses of amphetamine eventually results in

Tolerance development has been shown to occur for which of these psychostimulants?

The free-basing of cocaine is done to

What are some of the primary differences between cocaine and amphetamine?

In normal adult humans, alertness, decreased fatigue, improved ability to concentrate, and elevated mood are likely to be observed following administration of low doses of

Smoking "crack" cocaine is more likely to result in dependence than intranasal administration of cocaine because

Empirical evidence indicates that amphetamine's behavioral effects are

Cocaine and amphetamine differ most significantly in terms of their

Chronic use of cocaine can result in

Psychopharmacology in Perspective

Drug Classification and Behavioral Assessment

Basic Principles of Pharmacology

Excitability and Chemical Signaling in Nerve Cells

Synaptic Transmission, Drugs, and Chemical Neuroanatomy

Tolerance, Sensitization, Dependence, and Addiction

Antipsychotic Drugs and Neurochemical Hypotheses of Schizophrenia

Antidepressants and Mood Stabilizers

Sedative-Hypnotics, Anxiolytics, and Anticonvulsants

Drug Treatment of Cognitive Dysfunction

Naturally Occurring and Synthetic Opiates and Their Antagonists

Dissociative Anesthetics

Filters