Question 1

Which of the following statements about an SN1 reaction mechanism is true?

Accepted Answer

A)  The reaction is fastest with primary alkyl halide. 
B)  The reaction exhibits a one-step mechanism. 
C)  The reaction rate increases as the leaving group ability increases. 
D)  The reaction rate increases as the strength of the nucleophile increases. 
A)  The reaction is fastest with primary alkyl halide. 
B)  The reaction exhibits a one-step mechanism. 
C)  The reaction rate increases as the leaving group ability increases. 
D)  The reaction rate increases as the strength of the nucleophile increases.

Question 2

Which of the following is a polar aprotic solvent?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 3

The reaction of 1-bromobutane with sodium hydroxide affords the substitution product 1-butanol. What would happen to the rate of the reaction if the concentration of both 1-bromobutane and sodium hydroxide were doubled?

Accepted Answer

A)  The rate remains the same. 
B)  The rate decreases by a factor of 2. 
C)  The rate increases by a factor of 2. 
D)  The rate increases by a factor of 4. 
A)  The rate remains the same. 
B)  The rate decreases by a factor of 2. 
C)  The rate increases by a factor of 2. 
D)  The rate increases by a factor of 4.

Question 4

For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction.

Accepted Answer

A)  SN1, H2O 
B)  SN1, DMF 
C)  SN2, H2O 
D)  SN2, DMF 
A)  SN1, H2O 
B)  SN1, DMF 
C)  SN2, H2O 
D)  SN2, DMF

Which of the following statements about an S_N1 reaction mechanism is true?

Which of the following is a polar aprotic solvent?

The reaction of 1-bromobutane with sodium hydroxide affords the substitution product 1-butanol. What would happen to the rate of the reaction if the concentration of both 1-bromobutane and sodium hydroxide were doubled?

For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction.

Structure and Bonding

Acids and Bases

Introduction to Organic Molecules and Functional Groups

Alkanes

Stereochemistry

Understanding Organic Reactions

Alkyl Halides and Elimination Reactions

Alcohols, Ethers and Epoxides

Alkenes

Alkynes

Oxidation and Reduction

Mass Spectrometry and Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Radical Reactions

Conjugation, Resonance, and Dienes

Benzene and Aromatic Compounds

Electrophilic Aromatic Substitution

Carboxylic Acids and the Acidity of the O-H Bond

Introduction to Carbonyl Chemistry; Organometallic Reagents; Oxidation and Reduction

Aldehydes and Ketones Nucleophilic Addition

Carboxylic Acids and Derivatives

Substitution Reactions of Carbonyl Compounds at the Alpha-Carbon

Carbonyl Condensation Reactions

Amines

Carbon-Carbon Bond Forming Reactions in Organic Synthesis

Pericyclic Reactions

Carbohydrates

Amino Acids and Proteins

Lipids

Synthetic Polymers

Filters

Exam 7: Alkyl Halides and Nucleophilic Substitution

Which of the following statements about an SN1 reaction mechanism is true?

Which of the following is a polar aprotic solvent?

The reaction of 1-bromobutane with sodium hydroxide affords the substitution product 1-butanol. What would happen to the rate of the reaction if the concentration of both 1-bromobutane and sodium hydroxide were doubled?

For the following reaction, use the identity of the alkyl halide and nucleophile to determine which substitution mechanism occurs. Then determine which solvent affords the faster reaction.

Structure and Bonding

Acids and Bases

Introduction to Organic Molecules and Functional Groups

Alkanes

Stereochemistry

Understanding Organic Reactions

Alkyl Halides and Elimination Reactions

Alcohols, Ethers and Epoxides

Alkenes

Alkynes

Oxidation and Reduction

Mass Spectrometry and Infrared Spectroscopy

Nuclear Magnetic Resonance Spectroscopy

Radical Reactions

Conjugation, Resonance, and Dienes

Benzene and Aromatic Compounds

Electrophilic Aromatic Substitution

Carboxylic Acids and the Acidity of the O-H Bond

Introduction to Carbonyl Chemistry; Organometallic Reagents; Oxidation and Reduction

Aldehydes and Ketones Nucleophilic Addition

Carboxylic Acids and Derivatives

Substitution Reactions of Carbonyl Compounds at the Alpha-Carbon

Carbonyl Condensation Reactions

Amines

Carbon-Carbon Bond Forming Reactions in Organic Synthesis

Pericyclic Reactions

Carbohydrates

Amino Acids and Proteins

Lipids

Synthetic Polymers

Filters

Which of the following statements about an S_N1 reaction mechanism is true?