Exam 14: Sleep, Dreaming, and Circadian Rhythms

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The first mammalian circadian gene to have its structure characterized was

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Several large-scale longitudinal studies documented the sleep patterns and health of healthy volunteers for several years. They found that people who slept __________ hours per night tended to live the longest.

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Each cycle of sleep during a typical night tends to be about

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Orexin is synthesized by neurons in the

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Identify three areas of the brain that are involved in the regulation of sleep. What is thought to be the function of each area? Be sure to describe the evidence that has implicated them.

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The EEG of a cerveau isolé is desynchronized only during

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In one study, 8 volunteers reduced their sleep by 30 minutes per night until they did not want to reduce it further. A major finding was that

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Which of the following are commonly prescribed as hypnotics?

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In the neurotransplantation experiment by Ralph and colleagues, the suprachiasmatic nuclei (SCN) were transplanted from the fetuses of mutant hamsters that had abnormally brief free-running sleep-wake cycles into normal adult hamsters whose sleep-wake cycles had been abolished by SCN lesions. The transplants initiated __________ sleep-wake cycles in the recipients.

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Under free-running conditions, longer periods of wakefulness and are usually followed by

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Studies of __________ provided early evidence that the anterior hypothalamus is involved in sleep.

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The fact that giant sloths sleep 20 hours per day is a strong argument

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The practice of diagnosing people as neurotic pseudoinsomniacs stopped when it was discovered that many people

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Disorders of excessive sleep or sleepiness are classified as

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__________ theories of sleep presume that being awake somehow disrupts the homeostasis of the body, and sleep is required to restore it.

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People who claim to be nondreamers

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Describe three major discoveries about circadian rhythms. Explain why these particular discoveries are so important?

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According to the text,

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Theories postulating that sleep permits the body to recover from internal deficits produced by wakefulness are often referred to as

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Our current understanding of the molecular mechanisms of narcolepsy is largely attributable to the study of

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