Exam 18: Biopsychology of Psychiatric Disorders

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Haloperidol and other __________ bind effectively to D2 receptors but not to D1 receptors.

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butyrophenones

Many of the people who experience clinical depression also experience recurring periods of

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C

About what proportion of the adult population suffers from schizophrenia?

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C

One serious shortcoming of conventional animal models of anxiety is that they

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Fluoxetine, or __________, is an SSRI.

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Dopamine agonist is to dopamine antagonist as

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Benzodiazepines have been shown to reduce indices of fear and anxiety in the

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Because schizophrenia appears to be a neurodevelopmental disorder, several studies have tracked the development of brain damage in schizophrenic patients. Meta-analyses of these studies indicate that

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Several large scale studies have compared the effectiveness of various antidepressants to placebos. These studies have found that

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Clinical depression and anxiety are comorbid disorders, which means that they

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Determining the maximum safe dose for humans typically occurs in the __________ phase of human clinical trials.

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The dissociative anesthetics, such as ketamine,

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Studies of monozygotic and dizygotic twins suggest that schizophrenia

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Clozapine, like other atypical neuroleptics,

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The agonistic effects of __________ on GABAA receptors are thought to account for the clinical effectiveness of this class of drugs on anxiety disorders.

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A strict interpretation of the D2-version of the dopamine theory of schizophrenia cannot explain key findings. Discuss three of these findings and reach a conclusion.

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A major problem with the therapeutic use of neuroleptics in the treatment of schizophrenia is that they

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In functional brain-imaging studies of Tourette patients who are suppressing their tics, abnormal activity has been consistently observed in the caudate and

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Evidence that environmental factors play a role in the etiology of schizophrenia is that the concordance rate for identical twins is

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Chlorpromazine binds to dopamine receptors without activating them, and keeps dopamine from binding to them. Accordingly, chlorpromazine is classified as a

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