Question 1

Which group of small molecules best fit the boxes associated with the reaction shown?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 2

The citric acid cycle is considered part of aerobic metabolism even though oxygen does not appear explicitly in any reaction because

Accepted Answer

A)  the NADH and FADH2 produced are reoxidized in the electron transport chain linked to oxygen 
B)  the reoxidation of NADH and FADH2 leads to the production of considerable quantities of ATP 
C)  it takes place in the mitochondrion 
D)  it contains oxidation reactions 
A)  the NADH and FADH2 produced are reoxidized in the electron transport chain linked to oxygen 
B)  the reoxidation of NADH and FADH2 leads to the production of considerable quantities of ATP 
C)  it takes place in the mitochondrion 
D)  it contains oxidation reactions

Question 3

Each of the enzymes of the pyruvate dehydrogenase complex requires a different vitamin.

Accepted Answer

A) True 
 B)False

Question 4

Which enzyme catalyzes the reaction shown?

Accepted Answer

A)  isocitrate dehydrogenase 
B)  malate dehydrogenase 
C)  fumarase 
D)  succinate dehydrogenase 
A)  isocitrate dehydrogenase 
B)  malate dehydrogenase 
C)  fumarase 
D)  succinate dehydrogenase

Question 5

Which enzymes in the citric acid cycle catalyze oxidative decarboxylation reactions?

Accepted Answer

A)  isocitrate dehydrogenase and the a-ketoglutarate dehydrogenase complex 
B)  aconitase and succinate dehydrogenase 
C)  the a-ketoglutarate dehydrogenase complex and succinate thiokinase 
D)  fumarase and succinate dehydrogenase 
A)  isocitrate dehydrogenase and the a-ketoglutarate dehydrogenase complex 
B)  aconitase and succinate dehydrogenase 
C)  the a-ketoglutarate dehydrogenase complex and succinate thiokinase 
D)  fumarase and succinate dehydrogenase

Question 6

Which of the reactions of the citric acid cycle requires FAD as a coenzyme?

Accepted Answer

A)  the conversion of isocitrate to a-ketoglutarate 
B)  the conversion of citrate to isocitrate 
C)  the conversion of succinate to fumarate 
D)  the conversion of malate to oxaloacetate 
A)  the conversion of isocitrate to a-ketoglutarate 
B)  the conversion of citrate to isocitrate 
C)  the conversion of succinate to fumarate 
D)  the conversion of malate to oxaloacetate

Question 7

Which of the following enzymes is allosterically inhibited by ATP?

Accepted Answer

A)  pyruvate dehydrogenase complex 
B)  succinyl-CoA synthetase 
C)  succinate dehydrogenase 
D)  fumarase 
A)  pyruvate dehydrogenase complex 
B)  succinyl-CoA synthetase 
C)  succinate dehydrogenase 
D)  fumarase

Question 8

Which of the following reactions involves substrate-level phosphorylation?

Accepted Answer

A)  isocitrate a-ketoglutarate 
B)  citrate isocitrate 
C)  succinate fumarate 
D)  succinyl-CoA succinate 
A)  isocitrate a-ketoglutarate 
B)  citrate isocitrate 
C)  succinate fumarate 
D)  succinyl-CoA succinate

Question 9

The immediate electron acceptor for the majority of the oxidative reactions of the citric acid cycle is

Accepted Answer

A)  ATP. 
B)  NAD. 
C)  FAD. 
D)  coenzyme A 
A)  ATP. 
B)  NAD. 
C)  FAD. 
D)  coenzyme A

Question 10

In the classical equation for respiration: Glucose + 6O2 --> 6CO2 + 6H2O,the following molecules are found directly in the citric acid cycle:

Accepted Answer

A)  O2  
B)  Glucose and O2 
C)  CO2 and H2O 
D)  all of these arae found directly in the citric acid cycle 
A)  O2  
B)  Glucose and O2 
C)  CO2 and H2O 
D)  all of these arae found directly in the citric acid cycle

Question 11

The intracellular site of the glyoxylate cycle is

Accepted Answer

A)  glyoxysomes only. 
B)  glyoxysomes and lysosomes. 
C)  glyoxysomes and Golgi apparatus. 
D)  glyoxysomes and smooth endoplasmic reticulum. 
A)  glyoxysomes only. 
B)  glyoxysomes and lysosomes. 
C)  glyoxysomes and Golgi apparatus. 
D)  glyoxysomes and smooth endoplasmic reticulum.

Question 12

One round of the citric acid cycle generates about ten equivalents of ATP.

Accepted Answer

A) True 
 B)False

Question 13

A unique feature of the glyoxylate cycle is that it allows the organisms that possess this pathway to

Accepted Answer

A)  produce fats from carbohydrates. 
B)  produce carbohydrates from fats. 
C)  convert acetyl-CoA to pyruvate. 
D)  do all of the above. 
A)  produce fats from carbohydrates. 
B)  produce carbohydrates from fats. 
C)  convert acetyl-CoA to pyruvate. 
D)  do all of the above.

Question 14

Which enzyme catalyzes the reaction shown?

Accepted Answer

A)  succinyl-CoA synthetase 
B)  succinate dehydrogenase 
C)  pyruvate dehydrogenase 
D)  a-ketoglutarate dehydrogenase 
A)  succinyl-CoA synthetase 
B)  succinate dehydrogenase 
C)  pyruvate dehydrogenase 
D)  a-ketoglutarate dehydrogenase

Question 15

Which group of small molecules best fit the boxes associated with the reaction shown?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 16

Which coenzyme listed below is not associated with the a-ketoglutarate dehydrogenase complex?

Accepted Answer

A)  thiamine pyrophosphate 
B)  lipoic acid 
C)  biotin 
D)  NAD+ 
A)  thiamine pyrophosphate 
B)  lipoic acid 
C)  biotin 
D)  NAD+

Question 17

Which group of small molecules best fit the boxes associated with the reaction shown?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Exam 19: The Citric Acid Cycle

Which group of small molecules best fit the boxes associated with the reaction shown?

The citric acid cycle is considered part of aerobic metabolism even though oxygen does not appear explicitly in any reaction because

Each of the enzymes of the pyruvate dehydrogenase complex requires a different vitamin.

Which enzyme catalyzes the reaction shown?

Which enzymes in the citric acid cycle catalyze oxidative decarboxylation reactions?

Which of the reactions of the citric acid cycle requires FAD as a coenzyme?

Which of the following enzymes is allosterically inhibited by ATP?

Which of the following reactions involves substrate-level phosphorylation?

The immediate electron acceptor for the majority of the oxidative reactions of the citric acid cycle is

In the classical equation for respiration: Glucose + 6O2 --> 6CO2 + 6H2O,the following molecules are found directly in the citric acid cycle:

The intracellular site of the glyoxylate cycle is

One round of the citric acid cycle generates about ten equivalents of ATP.

A unique feature of the glyoxylate cycle is that it allows the organisms that possess this pathway to

Which enzyme catalyzes the reaction shown?

Which group of small molecules best fit the boxes associated with the reaction shown?

Which coenzyme listed below is not associated with the a-ketoglutarate dehydrogenase complex?

Which group of small molecules best fit the boxes associated with the reaction shown?

Biochemistry and the Organization of Cells

Water: The Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of Rna

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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In the classical equation for respiration: Glucose + 6O₂ --> 6CO₂ + 6H₂O,the following molecules are found directly in the citric acid cycle: