Question 1

An enzyme not involved in the control of glycolysis is

Accepted Answer

A)  hexokinase. 
B)  triose phosphate isomerase. 
C)  pyruvate kinase. 
D)  phosphofructokinase. 
A)  hexokinase. 
B)  triose phosphate isomerase. 
C)  pyruvate kinase. 
D)  phosphofructokinase. B

Question 2

The phosphorylation of glucose to glucose 6-phosphate

Accepted Answer

A)  is so strongly exergonic that it does not require a catalyst. 
B)  is an exergonic reaction not coupled to any other reaction. 
C)  is an endergonic reaction that takes place because it is coupled to the exergonic hydrolysis of ATP. 
D)  is an exergonic reaction that is coupled to the endergonic hydrolysis of ATP. 
A)  is so strongly exergonic that it does not require a catalyst. 
B)  is an exergonic reaction not coupled to any other reaction. 
C)  is an endergonic reaction that takes place because it is coupled to the exergonic hydrolysis of ATP. 
D)  is an exergonic reaction that is coupled to the endergonic hydrolysis of ATP. C

Question 3

Which of the following terms describes an enzyme that transfers a phosphate group from ATP to a substrate?

Accepted Answer

A)  kinase 
B)  isomerase 
C)  mutase 
D)  dehydrogenase 
A)  kinase 
B)  isomerase 
C)  mutase 
D)  dehydrogenase A

Question 4

Methanol is extremely toxic,but not directly.In the body,it is converted into formaldehyde; that's what's actually the poison.What kind of enzyme catalyses this conversion?

Accepted Answer

A)  a kinase 
B)  an isomerase 
C)  a mutase 
D)  a dehydrogenase 
A)  a kinase 
B)  an isomerase 
C)  a mutase 
D)  a dehydrogenase

Question 5

The phosphorylation of fructose 6-phosphate to fructose-1,6-bisphosphate is the committed step in glycolysis because

Accepted Answer

A)  it is the rate-limiting step. 
B)  it is the most strongly exergonic step in the pathway. 
C)  fructose 1,6-bisphosphate can undergo no other reactions than those of glycolysis. 
D)  two phosphate groups are involved. 
A)  it is the rate-limiting step. 
B)  it is the most strongly exergonic step in the pathway. 
C)  fructose 1,6-bisphosphate can undergo no other reactions than those of glycolysis. 
D)  two phosphate groups are involved.

Question 6

How many different reactions involve substrate-level phosphorylation during glycolysis?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  6 
A)  1 
B)  2 
C)  3 
D)  4 
E)  6

Question 7

Which of the following is not true?

Accepted Answer

A)  Every reaction in a metabolic pathway must have a negative DG, or the pathway cannot run. 
B)  the reaction with the largest negative ÄG is the hexokinase reaction 
C)  the overall pathway of glycolysis has a negative ÄG 
D)  all of these are true 
A)  Every reaction in a metabolic pathway must have a negative DG, or the pathway cannot run. 
B)  the reaction with the largest negative ÄG is the hexokinase reaction 
C)  the overall pathway of glycolysis has a negative ÄG 
D)  all of these are true

Question 8

The step that commits the cell to metabolize glucose is catalyzed by

Accepted Answer

A)  hexokinase. 
B)  phosphoglucomutase. 
C)  aldolase. 
D)  phosphofructokinase. 
A)  hexokinase. 
B)  phosphoglucomutase. 
C)  aldolase. 
D)  phosphofructokinase.

Question 9

The equilibrium for the formation of glyceraldehyde-3-phosphate from dihydroxyacetone phosphate is driven by

Accepted Answer

A)  the negative free energy change for the reaction. 
B)  having the product of the reaction continuously consumed. 
C)  coupling to ATP hydrolysis. 
D)  none of these 
A)  the negative free energy change for the reaction. 
B)  having the product of the reaction continuously consumed. 
C)  coupling to ATP hydrolysis. 
D)  none of these

Question 10

How many enzymes of glycolysis are control points for the pathway?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  All the enzymes serve as control points. 
A)  1 
B)  2 
C)  3 
D)  4 
E)  All the enzymes serve as control points.

Question 11

Glycolysis

Accepted Answer

A)  does not require O2 to generate energy. 
B)  requires O2 to generate energy. 
C)  is inhibited by O2. 
D)  rate is increased in the presence of O2. 
A)  does not require O2 to generate energy. 
B)  requires O2 to generate energy. 
C)  is inhibited by O2. 
D)  rate is increased in the presence of O2.

Question 12

Which group of small molecules best fit the boxes associated with the reaction shown?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 13

During glycolysis,ATP is synthesized from ADP and a phosphate group transferred from an acid anhydride.

Accepted Answer

A) True 
 B)False

Question 14

Which of the following is not true?

Accepted Answer

A)  Multiple isozymes of lactate dehydrogenase are used as clinical means for diagnosing heart attacks. 
B)  Two enzymes involved in anaerobic glycolysis are found as isozymes with 5 different forms 
C)  The M4 version of lactate dehydrogenase predominates in heart tissue 
D)  After a myocardial infarction, the blood serum levels of MH3 and H4 isozymes increase 
A)  Multiple isozymes of lactate dehydrogenase are used as clinical means for diagnosing heart attacks. 
B)  Two enzymes involved in anaerobic glycolysis are found as isozymes with 5 different forms 
C)  The M4 version of lactate dehydrogenase predominates in heart tissue 
D)  After a myocardial infarction, the blood serum levels of MH3 and H4 isozymes increase

Question 15

In the conversion of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate

Accepted Answer

A)  an alcohol group is phosphorylated. 
B)  an alcohol is oxidized to an aldehyde. 
C)  an alcohol is oxidized to a carboxylic acid. 
D)  an aldehyde is oxidized to a carboxylic acid. 
A)  an alcohol group is phosphorylated. 
B)  an alcohol is oxidized to an aldehyde. 
C)  an alcohol is oxidized to a carboxylic acid. 
D)  an aldehyde is oxidized to a carboxylic acid.

Question 16

The fate of NADH from glycolysis depends on whether conditions are anaerobic or aerobic.

Accepted Answer

A) True 
 B)False

Question 17

The percentage of energy captured as ATP during the conversion of glucose to lactate is closest to

Accepted Answer

A)  10%. 
B)  30%. 
C)  50%. 
D)  75%. 
E)  90%. 
A)  10%. 
B)  30%. 
C)  50%. 
D)  75%. 
E)  90%.

Question 18

Thiamine pyrophosphate is a coenzyme

Accepted Answer

A)  frequently encountered in oxidation-reduction reactions. 
B)  required for the phosphorylation of ADP. 
C)  involved in transfers of two-carbon groups. 
D)  involved in transfers of one-carbon groups. 
A)  frequently encountered in oxidation-reduction reactions. 
B)  required for the phosphorylation of ADP. 
C)  involved in transfers of two-carbon groups. 
D)  involved in transfers of one-carbon groups.

Question 19

When humans consume ethanol,the first step in its metabolism is:

Accepted Answer

A)  conversion to lactate 
B)  conversion to acetaldehyde 
C)  conversion to acetone 
D)  production of fat 
A)  conversion to lactate 
B)  conversion to acetaldehyde 
C)  conversion to acetone 
D)  production of fat

Question 20

The binding of glucose to hexokinase

Accepted Answer

A)  is an example of lock-and-key binding of a substrate to the active site of an enzyme. 
B)  is an example of induced-fit binding of a substrate to the active site of an enzyme. 
C)  differs from the binding of substrates to other kinases. 
D)  is not well characterized. 
A)  is an example of lock-and-key binding of a substrate to the active site of an enzyme. 
B)  is an example of induced-fit binding of a substrate to the active site of an enzyme. 
C)  differs from the binding of substrates to other kinases. 
D)  is not well characterized.

Exam 17: Glycolysis

An enzyme not involved in the control of glycolysis is

The phosphorylation of glucose to glucose 6-phosphate

Which of the following terms describes an enzyme that transfers a phosphate group from ATP to a substrate?

Methanol is extremely toxic,but not directly.In the body,it is converted into formaldehyde; that's what's actually the poison.What kind of enzyme catalyses this conversion?

The phosphorylation of fructose 6-phosphate to fructose-1,6-bisphosphate is the committed step in glycolysis because

How many different reactions involve substrate-level phosphorylation during glycolysis?

Which of the following is not true?

The step that commits the cell to metabolize glucose is catalyzed by

The equilibrium for the formation of glyceraldehyde-3-phosphate from dihydroxyacetone phosphate is driven by

How many enzymes of glycolysis are control points for the pathway?

Glycolysis

Which group of small molecules best fit the boxes associated with the reaction shown?

During glycolysis,ATP is synthesized from ADP and a phosphate group transferred from an acid anhydride.

Which of the following is not true?

In the conversion of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate

The fate of NADH from glycolysis depends on whether conditions are anaerobic or aerobic.

The percentage of energy captured as ATP during the conversion of glucose to lactate is closest to

Thiamine pyrophosphate is a coenzyme

When humans consume ethanol,the first step in its metabolism is:

The binding of glucose to hexokinase

Biochemistry and the Organization of Cells

Water: The Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of Rna

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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