Question 1

Which of the following glycolytic enzymes forms a mixed anhydride from phosphoric acid?

Accepted Answer

A)  hexokinase. 
B)  phosphofructokinase. 
C)  glyceraldehyde-3-phosphate dehydrogenase. 
D)  phosphoglycerate kinase. 
E)  pyruvate kinase. 
A)  hexokinase. 
B)  phosphofructokinase. 
C)  glyceraldehyde-3-phosphate dehydrogenase. 
D)  phosphoglycerate kinase. 
E)  pyruvate kinase. C

Question 2

The phosphorylation of glucose to glucose 6-phosphate

Accepted Answer

A)  is so strongly exergonic that it does not require a catalyst. 
B)  is an exergonic reaction not coupled to any other reaction. 
C)  is an endergonic reaction that takes place because it is coupled to the exergonic hydrolysis of ATP. 
D)  is an exergonic reaction that is coupled to the endergonic hydrolysis of ATP. 
A)  is so strongly exergonic that it does not require a catalyst. 
B)  is an exergonic reaction not coupled to any other reaction. 
C)  is an endergonic reaction that takes place because it is coupled to the exergonic hydrolysis of ATP. 
D)  is an exergonic reaction that is coupled to the endergonic hydrolysis of ATP. C

Question 3

When humans consume ethanol, the first step in its metabolism is:

Accepted Answer

A)  conversion to lactate 
B)  conversion to acetaldehyde 
C)  conversion to acetone 
D)  production of fat 
A)  conversion to lactate 
B)  conversion to acetaldehyde 
C)  conversion to acetone 
D)  production of fat B

Question 4

Which of the following enzymes forms a thioester using a cysteine residue as a key intermediate?

Accepted Answer

A)  hexokinase 
B)  triose phosphate isomerase 
C)  glyceraldehyde-3-phosphate dehydrogenase 
D)  enolase 
A)  hexokinase 
B)  triose phosphate isomerase 
C)  glyceraldehyde-3-phosphate dehydrogenase 
D)  enolase

Question 5

Which of the following terms describes an enzyme that catalyzes electron transfer reactions?

Accepted Answer

A)  dehydrogenase 
B)  isomerase 
C)  kinase 
D)  phosphatase 
A)  dehydrogenase 
B)  isomerase 
C)  kinase 
D)  phosphatase

Question 6

Fetal alcohol syndrome

Accepted Answer

A)  can be prevented by administering large doses of vitamin B1 to pregnant women 
B)  can be prevented by administering large doses of the vitamin niacin (nicotinic acid) to pregnant women 
C)  can be reversed by administering acetaldehyde 
D)  can be detected by measuring the level of acetaldehyde in the bloodstream of a pregnant woman 
A)  can be prevented by administering large doses of vitamin B1 to pregnant women 
B)  can be prevented by administering large doses of the vitamin niacin (nicotinic acid) to pregnant women 
C)  can be reversed by administering acetaldehyde 
D)  can be detected by measuring the level of acetaldehyde in the bloodstream of a pregnant woman

Question 7

Which of the following terms describes an enzyme that transfers a phosphate group from ATP to a substrate?

Accepted Answer

A)  kinase 
B)  isomerase 
C)  mutase 
D)  dehydrogenase 
A)  kinase 
B)  isomerase 
C)  mutase 
D)  dehydrogenase

Question 8

The enzyme glucokinase

Accepted Answer

A)  phosphorylates a number of different sugars, including glucose, fructose, and mannose. 
B)  specifically phosphorylates glucose rather than other sugars. 
C)  is the only kinase involved in glycolysis. 
D)  none of the above. 
A)  phosphorylates a number of different sugars, including glucose, fructose, and mannose. 
B)  specifically phosphorylates glucose rather than other sugars. 
C)  is the only kinase involved in glycolysis. 
D)  none of the above.

Question 9

Which of the following enzymes relies on thiamine pyrophosphate as a cofactor?

Accepted Answer

A)  pyruvate decarboxylase 
B)  pyruvate kinase 
C)  lactate dehydrogenase 
D)  enolase 
A)  pyruvate decarboxylase 
B)  pyruvate kinase 
C)  lactate dehydrogenase 
D)  enolase

Question 10

Enolase catalyzes

Accepted Answer

A)  the cleavage of fructose bisphosphate into two 3-carbon units. 
B)  the dehydration of 2-phosphoglycerate. 
C)  the conversion of phosphoenolpyruvate to pyruvate. 
D)  the conversion of glucose-6-phosphate to fructose-6-phosphate. 
A)  the cleavage of fructose bisphosphate into two 3-carbon units. 
B)  the dehydration of 2-phosphoglycerate. 
C)  the conversion of phosphoenolpyruvate to pyruvate. 
D)  the conversion of glucose-6-phosphate to fructose-6-phosphate.

Question 11

Which of the following is not true?

Accepted Answer

A)  Every reaction in a metabolic pathway must have a negative ΔG, or the pathway cannot run. 
B)  the reaction with the largest negative ÄG is the hexokinase reaction 
C)  the overall pathway of glycolysis has a negative ÄG 
D)  all of these are true 
A)  Every reaction in a metabolic pathway must have a negative ΔG, or the pathway cannot run. 
B)  the reaction with the largest negative ÄG is the hexokinase reaction 
C)  the overall pathway of glycolysis has a negative ÄG 
D)  all of these are true

Question 12

Which of the following enzymes of anaerobic metabolism is not tetrameric?

Accepted Answer

A)  Hexokinase 
B)  Phosphofructokinase 
C)  Pyruvate kinase 
D)  Lactate Dehydrogenase 
A)  Hexokinase 
B)  Phosphofructokinase 
C)  Pyruvate kinase 
D)  Lactate Dehydrogenase

Question 13

How many different reactions involve substrate-level phosphorylation during glycolysis?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  6 
A)  1 
B)  2 
C)  3 
D)  4 
E)  6

Question 14

Which of the following is not true?

Accepted Answer

A)  Corn is the only source of biofuels 
B)  Biofuels are related to glycolysis because fermentation is an end process of anaerobic glycolysis 
C)  Corn, wood, animal dung, and many other products can produce biofuels 
D)  Many carbohydrate sources can produce ethanol 
A)  Corn is the only source of biofuels 
B)  Biofuels are related to glycolysis because fermentation is an end process of anaerobic glycolysis 
C)  Corn, wood, animal dung, and many other products can produce biofuels 
D)  Many carbohydrate sources can produce ethanol

Question 15

Which enzyme catalyzes reaction the reaction shown?

Accepted Answer

A)  enolase 
B)  pyruvate dehydrogenase 
C)  pyruvate kinase 
D)  phosphoglycerate mutase 
A)  enolase 
B)  pyruvate dehydrogenase 
C)  pyruvate kinase 
D)  phosphoglycerate mutase

Question 16

Which of the following is true about phosphofructokinase?

Accepted Answer

A)  It is a tetramer composed of different combinations of the M and L subunits 
B)  there are two isozymes, M4 and L4 
C)  there are a total of 6 isozyme types in the body 
D)  It is a dimer composed of M and L subunits 
E)  none of these 
A)  It is a tetramer composed of different combinations of the M and L subunits 
B)  there are two isozymes, M4 and L4 
C)  there are a total of 6 isozyme types in the body 
D)  It is a dimer composed of M and L subunits 
E)  none of these

Question 17

What kind of enzyme catalyzes the reaction shown?

Accepted Answer

A)  an epimerase 
B)  an isomerase 
C)  a mutase 
D)  a dehydrogenase 
A)  an epimerase 
B)  an isomerase 
C)  a mutase 
D)  a dehydrogenase

Question 18

What is the relationship between glycolysis and cancer?

Accepted Answer

A)  cancer cells lack a glycolytic pathway 
B)  cancer cells use a modified version of glycolysis 
C)  cancer cells exhibit a much higher level of anaerobic glycolysis than normal cells 
D)  none of these 
A)  cancer cells lack a glycolytic pathway 
B)  cancer cells use a modified version of glycolysis 
C)  cancer cells exhibit a much higher level of anaerobic glycolysis than normal cells 
D)  none of these

Question 19

Which enzyme is the key regulatory enzyme in glycolysis?

Accepted Answer

A)  Glyceraldehyde-3-phosphate dehydrogenase 
B)  Enolase 
C)  Phosphofructokinase 
D)  Aldolase 
A)  Glyceraldehyde-3-phosphate dehydrogenase 
B)  Enolase 
C)  Phosphofructokinase 
D)  Aldolase

Question 20

An enzyme not involved in the control of glycolysis is

Accepted Answer

A)  hexokinase. 
B)  triose phosphate isomerase. 
C)  pyruvate kinase. 
D)  phosphofructokinase. 
A)  hexokinase. 
B)  triose phosphate isomerase. 
C)  pyruvate kinase. 
D)  phosphofructokinase.

Exam 17: Glycolysis

Which of the following glycolytic enzymes forms a mixed anhydride from phosphoric acid?

The phosphorylation of glucose to glucose 6-phosphate

When humans consume ethanol, the first step in its metabolism is:

Which of the following enzymes forms a thioester using a cysteine residue as a key intermediate?

Which of the following terms describes an enzyme that catalyzes electron transfer reactions?

Fetal alcohol syndrome

Which of the following terms describes an enzyme that transfers a phosphate group from ATP to a substrate?

The enzyme glucokinase

Which of the following enzymes relies on thiamine pyrophosphate as a cofactor?

Enolase catalyzes

Which of the following is not true?

Which of the following enzymes of anaerobic metabolism is not tetrameric?

How many different reactions involve substrate-level phosphorylation during glycolysis?

Which of the following is not true?

Which enzyme catalyzes reaction the reaction shown?

Which of the following is true about phosphofructokinase?

What kind of enzyme catalyzes the reaction shown?

What is the relationship between glycolysis and cancer?

Which enzyme is the key regulatory enzyme in glycolysis?

An enzyme not involved in the control of glycolysis is

Biochemistry and the Organization of Cells

Water: the Solvent for Biochemical Reactions

Amino Acids and Peptides

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of RNA

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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