Question 1

Which is the C-terminal amino acid in the peptide ALA-GLN-ARG-SER-HIS?

Accepted Answer

A)  ALA 
B)  GLN 
C)  ARG 
D)  SER 
E)  HIS 
A)  ALA 
B)  GLN 
C)  ARG 
D)  SER 
E)  HIS

Question 2

$$\begin{array}{l}
\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\
\begin{array} { l l l l } 
\text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \
\hline \text { Ala } & 2.3 & 9.7 & \
\text { Arg } & 2.2 & 9.0 & 12.5 \
\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \
\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \
\text { Cys } & 1.7 & 10.8 & 6.0 \
\text { His } & 1.8 & 9.2 & \
\text { Ser } & 2.2 & 9.2 & 10.1
\end{array}
\end{array}$$
-Refer to Exhibit 3A. At pH 7, what percent of histidine has a neutral charge?

Accepted Answer

A)  9% 
B)  50% 
C)  91% 
D)  100% 
A)  9% 
B)  50% 
C)  91% 
D)  100%

Question 3

Which amino acid would have the greatest negative charge at pH = 7.0?

Accepted Answer

A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine 
A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine

Question 4

Which of the following can be considered a unique characteristic of histidine?

Accepted Answer

A)  Its side chain is attached to the alpha carbon 
B)  It has a basic side chain 
C)  It has a side chain that is chemically basic but has an acidic pKa 
D)  It is technically an "imino" acid 
A)  Its side chain is attached to the alpha carbon 
B)  It has a basic side chain 
C)  It has a side chain that is chemically basic but has an acidic pKa 
D)  It is technically an "imino" acid

Question 5

Which of the following is not considered an uncommon amino acid?

Accepted Answer

A)  thyroxine 
B)  Hydroxylysine 
C)  Hydroxyproline 
D)  Tryptophan 
A)  thyroxine 
B)  Hydroxylysine 
C)  Hydroxyproline 
D)  Tryptophan

Question 6

Which amino acid has the least polar R-group H?

Accepted Answer

A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine 
A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine

Question 7

Oxytocin and vasopressin

Accepted Answer

A)  differ from each other by a single amino acid 
B)  do not contain sulfur 
C)  are peptide hormones 
D)  are tripeptides 
A)  differ from each other by a single amino acid 
B)  do not contain sulfur 
C)  are peptide hormones 
D)  are tripeptides

Question 8

Given the R-groups in the peptide, ALA-GLN-ARG-SER-HIS, it would likely be:

Accepted Answer

A)  Very water soluble 
B)  Somewhat water soluble 
C)  Not very water soluble 
D)  Not soluble at all 
E)  You cannot tell from the sequence 
A)  Very water soluble 
B)  Somewhat water soluble 
C)  Not very water soluble 
D)  Not soluble at all 
E)  You cannot tell from the sequence

Question 9

$$\begin{array}{l}
\text { Exhibit } \mathbf { 3 A } \text { (for this chapter) }\
\begin{array} { l l l l } 
\text { Amino acid } & \boldsymbol { \alpha } \text {-carboxyl group pK a } & \boldsymbol { \alpha } \text {-amino group pK a } & \text { R-group pK } \
\hline \text { Ala } & 2.3 & 9.7 & \
\text { Arg } & 2.2 & 9.0 & 12.5 \
\text { Asn or Gln } & 2.1 & 9.0 & 4.0 \
\text { Asp or Glu } & 2.2 & 9.8 & 8.3 \
\text { Cys } & 1.7 & 10.8 & 6.0 \
\text { His } & 1.8 & 9.2 & \
\text { Ser } & 2.2 & 9.2 & 10.1
\end{array}
\end{array}$$
-Refer to Exhibit 3A. Which one has a pI of 5.0?

Accepted Answer

A)  Alanine 
B)  Arginine 
C)  Histidine 
D)  Cysteine 
E)  Glutamic acid 
A)  Alanine 
B)  Arginine 
C)  Histidine 
D)  Cysteine 
E)  Glutamic acid

Question 10

Which of the following correctly lists the isoelectric pH's of asp, asn, and arg from lowest to highest?

Accepted Answer

A)  D N R 
B)  D R N 
C)  R N D 
D)  R D N 
E)  N R D
F) N D R 
A)  D N R 
B)  D R N 
C)  R N D 
D)  R D N 
E)  N R D
F) N D R

Question 11

Which groups of a pair of amino acids must react to form a peptide bond?

Accepted Answer

A)  the two carboxyls 
B)  the two aminos 
C)  the two R-groups 
D)  the carboxyl of one and the amino of the other 
A)  the two carboxyls 
B)  the two aminos 
C)  the two R-groups 
D)  the carboxyl of one and the amino of the other

Question 12

Which amino acid has a basic R group?

Accepted Answer

A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine 
A)  Glutamic Acid 
B)  Histidine 
C)  Isoleucine 
D)  Serine 
E)  Tyrosine

Question 13

The order in which amino acids are linked in peptides is given

Accepted Answer

A)  from the C-terminal to the N-terminal end 
B)  from the N-terminal to the C-terminal end 
C)  in alphabetical order 
D)  in order of increasing molecular weights of the amino acid residues 
A)  from the C-terminal to the N-terminal end 
B)  from the N-terminal to the C-terminal end 
C)  in alphabetical order 
D)  in order of increasing molecular weights of the amino acid residues

Question 14

Which amino acid has the three-letter symbol asn?

Accepted Answer

A)  aspartic acid 
B)  asparagine 
C)  alanine 
D)  arginine 
A)  aspartic acid 
B)  asparagine 
C)  alanine 
D)  arginine

Question 15

Exhibit 3B A titration curve.
  
-Refer to Exhibit 3B. Which point most likely represents the pK for the carboxyl group?

Accepted Answer

A)  1 
B)  2 
C)  3 
D)  4 
E)  5 
A)  1 
B)  2 
C)  3 
D)  4 
E)  5

Which is the C-terminal amino acid in the peptide ALA-GLN-ARG-SER-HIS?

Exhibit (for this chapter) Amino acid -carboxyl group pK a -amino group pK a R-group pK Ala 2.3 9.7 Arg 2.2 9.0 12.5 Asn or Gln 2.1 9.0 4.0 Asp or Glu 2.2 9.8 8.3 Cys 1.7 10.8 6.0 His 1.8 9.2 Ser 2.2 9.2 10.1 -Refer to Exhibit 3A. At pH 7, what percent of histidine has a neutral charge?

Which amino acid would have the greatest negative charge at pH = 7.0?

Which of the following can be considered a unique characteristic of histidine?

Which of the following is not considered an uncommon amino acid?

Which amino acid has the least polar R-group H?

Oxytocin and vasopressin

Given the R-groups in the peptide, ALA-GLN-ARG-SER-HIS, it would likely be:

Exhibit (for this chapter) Amino acid -carboxyl group pK a -amino group pK a R-group pK Ala 2.3 9.7 Arg 2.2 9.0 12.5 Asn or Gln 2.1 9.0 4.0 Asp or Glu 2.2 9.8 8.3 Cys 1.7 10.8 6.0 His 1.8 9.2 Ser 2.2 9.2 10.1 -Refer to Exhibit 3A. Which one has a pI of 5.0?

Which of the following correctly lists the isoelectric pH's of asp, asn, and arg from lowest to highest?

Which groups of a pair of amino acids must react to form a peptide bond?

Which amino acid has a basic R group?

The order in which amino acids are linked in peptides is given

Which amino acid has the three-letter symbol asn?

Exhibit 3B A titration curve. -Refer to Exhibit 3B. Which point most likely represents the pK for the carboxyl group?

Biochemistry and the Organization of Cells

Water: the Solvent for Biochemical Reactions

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of RNA

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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Exam 3: Amino Acids and Peptides

Which is the C-terminal amino acid in the peptide ALA-GLN-ARG-SER-HIS?

Exhibit (for this chapter) Amino acid -carboxyl group pK a -amino group pK a R-group pK Ala 2.3 9.7 Arg 2.2 9.0 12.5 Asn or Gln 2.1 9.0 4.0 Asp or Glu 2.2 9.8 8.3 Cys 1.7 10.8 6.0 His 1.8 9.2 Ser 2.2 9.2 10.1 -Refer to Exhibit 3A. At pH 7, what percent of histidine has a neutral charge?

Which amino acid would have the greatest negative charge at pH = 7.0?

Which of the following can be considered a unique characteristic of histidine?

Which of the following is not considered an uncommon amino acid?

Which amino acid has the least polar R-group H?

Oxytocin and vasopressin

Given the R-groups in the peptide, ALA-GLN-ARG-SER-HIS, it would likely be:

Exhibit (for this chapter) Amino acid -carboxyl group pK a -amino group pK a R-group pK Ala 2.3 9.7 Arg 2.2 9.0 12.5 Asn or Gln 2.1 9.0 4.0 Asp or Glu 2.2 9.8 8.3 Cys 1.7 10.8 6.0 His 1.8 9.2 Ser 2.2 9.2 10.1 -Refer to Exhibit 3A. Which one has a pI of 5.0?

Which of the following correctly lists the isoelectric pH's of asp, asn, and arg from lowest to highest?

Which groups of a pair of amino acids must react to form a peptide bond?

Which amino acid has a basic R group?

The order in which amino acids are linked in peptides is given

Which amino acid has the three-letter symbol asn?

Exhibit 3B A titration curve. -Refer to Exhibit 3B. Which point most likely represents the pK for the carboxyl group?

Biochemistry and the Organization of Cells

Water: the Solvent for Biochemical Reactions

The Three-Dimensional Structure of Proteins

Protein Purification and Characterization Techniques

The Behavior of Proteins: Enzymes

The Behavior of Proteins: Enzymes, Mechanisms, and Control

Lipids and Proteins Are Associated in Biological Membranes

Nucleic Acids: How Structure Conveys Information

Biosynthesis of Nucleic Acids: Replication

Transcription of the Genetic Code: Biosynthesis of RNA

Protein Synthesis: Translation of the Genetic Message

Nucleic Acid Biotechnology Techniques

Viruses, Cancer, and Immunology

The Importance of Energy Changes and Electron Transfer in Metabolism

Carbohydrates

Glycolysis

Storage Mechanisms and Control in Carbohydrate Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Lipid Metabolism

Photosynthesis

The Metabolism of Nitrogen

Integration of Metabolism: Cellular Signaling

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