Question 1

Match the enzymes with their functions in lipid metabolism.
-lipoprotein lipase

Accepted Answer

A) creates a double bond in a fatty acid 
B) removes triacylglycerol from plasma 
C) mobilizes stored triacylglycerols from adipocytes 
D) rate-limiting enzyme in cholesterol synthesis 
E) creates prostaglandins 
A) creates a double bond in a fatty acid 
B) removes triacylglycerol from plasma 
C) mobilizes stored triacylglycerols from adipocytes 
D) rate-limiting enzyme in cholesterol synthesis 
E) creates prostaglandins

Question 2

Ketogenesis would be the HIGHEST ____.

Accepted Answer

A) after a high-CHO meal 
B) after a high-protein meal 
C) after a high-fat meal 
D) during prolonged starvation 
A) after a high-CHO meal 
B) after a high-protein meal 
C) after a high-fat meal 
D) during prolonged starvation

Question 3

Which fatty acid is considered essential and must be supplied by the diet?

Accepted Answer

A) arachidonic acid 
B) omega-9 fatty acid 
C) linoleic acid 
D) oleic acid 
A) arachidonic acid 
B) omega-9 fatty acid 
C) linoleic acid 
D) oleic acid

Question 4

How does orlistat reduce absorption of dietary fat?

Accepted Answer

A) by replacing dietary fat with a synthetic, indigestible substitute 
B) by inhibiting the activity of pancreatic lipase 
C) by binding free fatty acids and causing their excretion 
D) by inhibiting HMG-CoA reductase 
A) by replacing dietary fat with a synthetic, indigestible substitute 
B) by inhibiting the activity of pancreatic lipase 
C) by binding free fatty acids and causing their excretion 
D) by inhibiting HMG-CoA reductase

Question 5

Match the lipid with the cardiovascular disease risk.
-lipoprotein (a)

Accepted Answer

A) atherogenic fatty plaque 
B) hypercholesterolemia 
C) raise LDL-C/lower HDL-C 
D) structural homology with plasminogen; increased risk of CVD 
E) increases LDL's affinity for macrophage receptors causing plaque 
A) atherogenic fatty plaque 
B) hypercholesterolemia 
C) raise LDL-C/lower HDL-C 
D) structural homology with plasminogen; increased risk of CVD 
E) increases LDL's affinity for macrophage receptors causing plaque

Question 6

What is the most important unsaturated fatty acid serving as a precursor for eicosanoid synthesis?

Accepted Answer

A) arachidonic acid 
B) palmitoleic acid 
C) oleic acid 
D) linoleic acid 
A) arachidonic acid 
B) palmitoleic acid 
C) oleic acid 
D) linoleic acid

Question 7

What is the carrier molecule needed for mitochondrial membrane transport of long-chain fatty acids and their CoA derivatives?

Accepted Answer

A) carnitine 
B) creatine 
C) creatinine 
D) cysteine 
A) carnitine 
B) creatine 
C) creatinine 
D) cysteine

Question 8

The conversion of linoleic acid (18:2)to arachidonic acid (20:4)involves the addition of two carbons to the methyl end and two double bonds at the n-3 and n-6 positions of the omega end.

Accepted Answer

A) True 
 B)False

Question 9

When foam cells,additional monocytes,mast cells,and T-cells build up in the media and intima of an artery,which structure is formed?

Accepted Answer

A) atheroma 
B) hamartoma 
C) neuroma 
D) arterioma 
A) atheroma 
B) hamartoma 
C) neuroma 
D) arterioma

Question 10

The HDL accomplishes its function in reverse cholesterol transport in two ways.Choose the phrase that does NOT describe one of these.

Accepted Answer

A) increased apoC-2 activity to reduce its triacylglycerol content 
B) increased activity of LCAT on vascular endothelial cells 
C) increased activity of transferring cholesterol to other lipoproteins 
D) using its apoE component to bind to LDL receptors 
A) increased apoC-2 activity to reduce its triacylglycerol content 
B) increased activity of LCAT on vascular endothelial cells 
C) increased activity of transferring cholesterol to other lipoproteins 
D) using its apoE component to bind to LDL receptors

Question 11

Which type of acid is linoleic acid?

Accepted Answer

A) n-9 
B) n-7 
C) n-6 
D) n-3 
A) n-9 
B) n-7 
C) n-6 
D) n-3

Question 12

How does hypertension increase the risk for CVD?

Accepted Answer

A) It damages white blood cells. 
B) It damages red blood cells. 
C) It leads to a disturbed repair process in arteries leading to aneurysms. 
D) It increases the risk of thromboses in veins. 
A) It damages white blood cells. 
B) It damages red blood cells. 
C) It leads to a disturbed repair process in arteries leading to aneurysms. 
D) It increases the risk of thromboses in veins.

Question 13

The regulation of fatty acid synthesis and oxidation is closely linked to carbohydrate status.

Accepted Answer

A) True 
 B)False

Question 14

Fatty acids are converted into glucose by gluconeogenesis and used for energy during starvation.

Accepted Answer

A) True 
 B)False

Question 15

HMG-CoA reductase is a key enzyme in the synthesis of cholesterol from acetyl-CoA.

Accepted Answer

A) True 
 B)False

Question 16

Apolipoproteins are unable to ____.

Accepted Answer

A) stimulate enzymatic reactions that regulate the metabolic functions of lipoproteins 
B) stabilize circulating lipoproteins in the blood 
C) decrease the density of the lipoprotein 
D) confer specificity for recognition by receptors on cells 
A) stimulate enzymatic reactions that regulate the metabolic functions of lipoproteins 
B) stabilize circulating lipoproteins in the blood 
C) decrease the density of the lipoprotein 
D) confer specificity for recognition by receptors on cells

Question 17

Explain the role of the MEOS and cytochrome P-450 in developing metabolic tolerance to ethanol.

Accepted Answer

​Grading rubric - answer should include

Question 18

Abnormal LDL receptors fail to remove cholesterol from the bloodstream,resulting in ____.

Accepted Answer

A) suppression of acyl-CoA cholesteryl acyl transferase (ACAT) 
B) suppression of 3-hydroxy-3-methylglutaryl-CoA (HMG-Co
A)  reductase 
C) hypertriglyceridemia 
D) familial hypercholesterolemia 
A) suppression of acyl-CoA cholesteryl acyl transferase (ACAT) 
B) suppression of 3-hydroxy-3-methylglutaryl-CoA (HMG-Co
A)  reductase 
C) hypertriglyceridemia 
D) familial hypercholesterolemia

Question 19

Explain the regulation of the allosteric enzyme acetyl-CoA carboxylase by citrate and palmitoyl-CoA.

Accepted Answer

​
Citrate - allosterically sti

Question 20

Cocoa butter contains which saturated fatty acid?

Accepted Answer

A) palmitic 
B) stearic 
C) arachidic 
D) myristic 
A) palmitic 
B) stearic 
C) arachidic 
D) myristic

Match the enzymes with their functions in lipid metabolism. -lipoprotein lipase

Ketogenesis would be the HIGHEST ____.

Which fatty acid is considered essential and must be supplied by the diet?

How does orlistat reduce absorption of dietary fat?

Match the lipid with the cardiovascular disease risk. -lipoprotein (a)

What is the most important unsaturated fatty acid serving as a precursor for eicosanoid synthesis?

What is the carrier molecule needed for mitochondrial membrane transport of long-chain fatty acids and their CoA derivatives?

The conversion of linoleic acid (18:2)to arachidonic acid (20:4)involves the addition of two carbons to the methyl end and two double bonds at the n-3 and n-6 positions of the omega end.

When foam cells,additional monocytes,mast cells,and T-cells build up in the media and intima of an artery,which structure is formed?

The HDL accomplishes its function in reverse cholesterol transport in two ways.Choose the phrase that does NOT describe one of these.

Which type of acid is linoleic acid?

How does hypertension increase the risk for CVD?

The regulation of fatty acid synthesis and oxidation is closely linked to carbohydrate status.

Fatty acids are converted into glucose by gluconeogenesis and used for energy during starvation.

HMG-CoA reductase is a key enzyme in the synthesis of cholesterol from acetyl-CoA.

Apolipoproteins are unable to ____.

Explain the role of the MEOS and cytochrome P-450 in developing metabolic tolerance to ethanol.

Abnormal LDL receptors fail to remove cholesterol from the bloodstream,resulting in ____.

Explain the regulation of the allosteric enzyme acetyl-CoA carboxylase by citrate and palmitoyl-CoA.

Cocoa butter contains which saturated fatty acid?

The Cell: A Microcosm of Life

The Digestive System: Mechanism for Nourishing the Body

Carbohydrates

Fiber

Protein

Integration and Regulation of Metabolism and the Impact of Exercise

Energy Expenditure, Body Composition, and Healthy Weight

Water-Soluble Vitamins

Fat-Soluble Vitamins

Major Minerals

Water and Electrolytes

Essential Trace and Ultratrace Minerals

Nonessential Trace and Ultratrace Minerals

Filters

Exam 5: Lipids

Match the enzymes with their functions in lipid metabolism. -lipoprotein lipase

Ketogenesis would be the HIGHEST ____.

Which fatty acid is considered essential and must be supplied by the diet?

How does orlistat reduce absorption of dietary fat?

Match the lipid with the cardiovascular disease risk. -lipoprotein (a)

What is the most important unsaturated fatty acid serving as a precursor for eicosanoid synthesis?

What is the carrier molecule needed for mitochondrial membrane transport of long-chain fatty acids and their CoA derivatives?

The conversion of linoleic acid (18:2)to arachidonic acid (20:4)involves the addition of two carbons to the methyl end and two double bonds at the n-3 and n-6 positions of the omega end.

When foam cells,additional monocytes,mast cells,and T-cells build up in the media and intima of an artery,which structure is formed?

The HDL accomplishes its function in reverse cholesterol transport in two ways.Choose the phrase that does NOT describe one of these.

Which type of acid is linoleic acid?

How does hypertension increase the risk for CVD?

The regulation of fatty acid synthesis and oxidation is closely linked to carbohydrate status.

Fatty acids are converted into glucose by gluconeogenesis and used for energy during starvation.

HMG-CoA reductase is a key enzyme in the synthesis of cholesterol from acetyl-CoA.

Apolipoproteins are unable to ____.

Explain the role of the MEOS and cytochrome P-450 in developing metabolic tolerance to ethanol.

Abnormal LDL receptors fail to remove cholesterol from the bloodstream,resulting in ____.

Explain the regulation of the allosteric enzyme acetyl-CoA carboxylase by citrate and palmitoyl-CoA.

Cocoa butter contains which saturated fatty acid?

The Cell: A Microcosm of Life

The Digestive System: Mechanism for Nourishing the Body

Carbohydrates

Fiber

Protein

Integration and Regulation of Metabolism and the Impact of Exercise

Energy Expenditure, Body Composition, and Healthy Weight

Water-Soluble Vitamins

Fat-Soluble Vitamins

Major Minerals

Water and Electrolytes

Essential Trace and Ultratrace Minerals

Nonessential Trace and Ultratrace Minerals

Filters