Exam 37: Gas Exchange & Transport

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If anything decreases alveolar PO₂, how does that affect the alveolar-blood oxygen pressure gradient?

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The presence of hemoglobin in the blood approximately doubles the oxygen-carrying capacity of plasma alone.

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Hemoglobin is made up of four polypeptide chains: an alpha, a beta, a gamma, and a delta.

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An increase in the partial pressure of carbon dioxide decreases the affinity between hemoglobin and oxygen. This is called a right shift, or the Haldane effect.

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One factor that determines the amount of oxygen transferred from the lungs to the blood is the total functional surface area of the respiratory membrane.

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To produce the highest possible oxygen concentration in the blood, gas exchange occurs in only one direction at the respiratory membrane-from the lung to the blood.

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There are six iron atoms in a single hemoglobin molecule.

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One reason that carbon monoxide gas is so dangerous is that it attaches to hemoglobin more readily than does oxygen gas.

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Blood is distributed through the capillaries in a layer so thin that each red blood cell comes in contact with the alveolar-capillary membrane.

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An increase in the plasma PCO₂ and a decrease in PO₂ cause an increase in the dissociation of CO₂ from hemoglobin.

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