Exam 3: Bioenergetics, Enzymes and Metabolism

You are observing an enzyme driven reaction. You add chemical X, which inhibits the reaction. If you add more substrate, the reaction rate approaches the V_max of the uninhibited reaction. Furthermore, the structure of X is similar to the natural substrate. What kind of inhibitor is X?

What kind of inhibitor binds very tightly to an enzyme often forming a covalent bond with an amino acid in the active site?

Which reaction below might be a suitable coupled reaction for the reaction A + B -> C + D ( $\Delta$ G = -8.7 kcal/mole)?

Doubling the concentration of enzyme will ______ the V_max and _____ the K_M.

Enzymes work by ___________.

Phosphorylation of glucose by hexokinase and phosphofructokinase is advantageous because:

2-[¹⁸F] fluoro-2-deoxy-D-glucose (FDG)acts as a competitive inhibitor of ______________.

Advantages derived from the use of a circadian oscillator regulatory mechanism include:

Other than controlling the synthesis of photosynthesis-related proteins and other factors, which process has been observed in plants to be regulated by the circadian oscillator?

Glycolysis occurs in the ________; the Krebs (TCA)cycle occurs in the ______ of eukaryotes and the ______ of prokaryotes.

Reactions that lose heat are termed:

Why has the pharmaceutical industry drastically cut resources devoted to the development of new antibiotics? (Select all correct choices)

Which statements accurately describe the metabolism and detection of tumor cells? (Select all that are correct choices)

The first exergonic reaction of glycolysis creates:

What is the activity of dehydrogenase enzymes destined to provide in a cell capable of respiration?

Entropy is associated with the _________ movement of particles of matter, which because they are ________ cannot accomplish a directed work process.

If mice are maintained on very strict diets with reduced caloric intake, what happens to their life span as compared to littermates fed diets with normal caloric content and why? (Select all correct responses)

Who was the first scientist to determine the structure and composition of an enzyme?

Tumor imaging can exploit soft tissue differences between normal and malignant cells by using all of the following EXCEPT:

A pharmacist is looking for a drug which will prevent an enzyme from working by binding to it as an inhibitor. Which of the inhibitors listed as choices will prove most effective, given equality in other considerations such as solubility, toxicity and stability?