Exam 22: Protein Synthesis

Coupling of transcription and translation occurs in both animal and bacterial cells.

Amino acids are attached to tRNA at the .

The net effect of all amino acid tRNA synthetases binding to a tRNA is to position the of tRNA in the active site.

Release factors fit into the A site when one of three codons UGA, UAG, or UAA is positioned there.

After proteins emerge from the ribosome, the N-terminal end starts to fold even before the entire protein is made.

In eukaryotes what is the function of eIF-4 cap binding protein)?

For each amino acid added to a polypeptide chain, phosphoanhydride bonds are cleaved.

EF-Ts promotes the dissociation of GDP from the EF-Tu-GDP complex to recycle this elongation factor.

Streptomycin can be used clinically because it inhibits bacterial protein synthesis but not eukaryotic protein synthesis.

When an oligosaccharide is covalently bonded to an asparagine or other amino acid) side chain, the resulting product is an)

Translation begins to be terminated when

Different tRNA molecules that bind the same amino acid are called tRNA molecules.

Which is not true about the genetic code?

Proteins destined to enter a cell membrane contain a signal peptide at the C-terminal end of the peptide.

What statement is not true about the Shine-Dalgarno sequence?

Ribosomal protein synthesis is controlled by inhibitor proteins, the genes of which are located on the ribosomal protein operon, and which bind to when ribosome assembly slows and bind to when ribosome assembly is proceeding at a steady rate.

The acceptor stem of tRNA consists of the .

Which statement is true about the attenuation mechanism of regulation?

The reading frame of DNA is fixed by

Isoacceptor tRNAs can only differ in primary sequence at the anticodon.