Question 1

In any species, the % A + T is equal to the % G +C.

Accepted Answer

A) True 
 B)False  False

Question 2

Prokaryotic DNA is organized into protein-DNA structures called nucleoids.

Accepted Answer

A) True 
 B)False  True

Question 3

Which is not a biological function of RNA?

Accepted Answer

A)  Participates in the modification of newly synthesized RNA. 
B)  It is the genome of some viruses. 
C)  Serves as a scaffold component for chromosomes. 
D)  Composes an integral part of the ribosome. 
E)  None of the above; all are functions of RNA 
A)  Participates in the modification of newly synthesized RNA. 
B)  It is the genome of some viruses. 
C)  Serves as a scaffold component for chromosomes. 
D)  Composes an integral part of the ribosome. 
E)  None of the above; all are functions of RNA E

Question 4

Which is not a difference between RNA and DNA?

Accepted Answer

A)  The sugar ring of RNA is more oxidized than that in DNA. 
B)  RNA contains uracil; DNA usually does not. 
C)  RNA cannot form helices. 
D)  RNA is single-stranded; DNA is double-stranded. 
A)  The sugar ring of RNA is more oxidized than that in DNA. 
B)  RNA contains uracil; DNA usually does not. 
C)  RNA cannot form helices. 
D)  RNA is single-stranded; DNA is double-stranded.

Question 5

As B-DNA is gradually heated, the absorbance at 260 nm

Accepted Answer

A)  increases. 
B)  decreases. 
C)  stays the same. 
D)  is half way between that of poly AT and poly G
C) . 
A)  increases. 
B)  decreases. 
C)  stays the same. 
D)  is half way between that of poly AT and poly G
C) .

Question 6

About how many nucleosomes could be made from a DNA strand consisting of 1000 base pairs?

Accepted Answer

A)  5 
B)  50 
C)  500 
D)  This is not enough DNA to make even one nucleosome. 
A)  5 
B)  50 
C)  500 
D)  This is not enough DNA to make even one nucleosome.

Question 7

Which of the following is mismatched?

Accepted Answer

A)  Miescher - discovery of DNA 
B)  Avery - DNA is the genetic material 
C)  Watson - DNA structure 
D)  Hoppe-Seyler - DNA sequence 
A)  Miescher - discovery of DNA 
B)  Avery - DNA is the genetic material 
C)  Watson - DNA structure 
D)  Hoppe-Seyler - DNA sequence

Question 8

All genomes are composed of RNA.

Accepted Answer

A) True 
 B)False

Question 9

In any species, the ratio of the % A + T to the % G + C is constant.

Accepted Answer

A) True 
 B)False

Question 10

It is easier to melt DNA richer in AT than GC because

Accepted Answer

A)  it is more heat sensitive. 
B)  there is one less hydrogen bond. 
C)  the helix pitch is longer in AT rich regions. 
D)  All of the above 
A)  it is more heat sensitive. 
B)  there is one less hydrogen bond. 
C)  the helix pitch is longer in AT rich regions. 
D)  All of the above

Question 11

Five different bases are found in most DNA and RNA molecules.

Accepted Answer

A) True 
 B)False

Question 12

DNA wraps around an octamer of histones to form bead-like structures called .

Accepted Answer

A)  nucleoids 
B)  nucleosomes 
C)  nucleoli 
D)  chromatids 
A)  nucleoids 
B)  nucleosomes 
C)  nucleoli 
D)  chromatids

Question 13

It is often not possible to determine the exact sequence of large polynucleotides such as RNA and DNA.

Accepted Answer

A) True 
 B)False

Question 14

The packaging of DNA in cells results in about a -fold reduction in length compared to the fully extended DNA fully stretched out).

Accepted Answer

A)  10 
B)  700 
C)  8000 
D)  200,000 
A)  10 
B)  700 
C)  8000 
D)  200,000

Question 15

Which best describes the structure of a nucleosome core particle?

Accepted Answer

A)  A histone octamer with DNA threaded through its center. 
B)  About 50 bp of DNA associated with one histone H1 molecule. 
C)  One nucleosome plus one histone H1 and linker DNA. 
D)  A histone octamer wrapped approximately two times around with DNA. 
A)  A histone octamer with DNA threaded through its center. 
B)  About 50 bp of DNA associated with one histone H1 molecule. 
C)  One nucleosome plus one histone H1 and linker DNA. 
D)  A histone octamer wrapped approximately two times around with DNA.

Question 16

Chromatin was first observed and named by .

Accepted Answer

A)  Walter Flemming 
B)  Francis Crick 
C)  Oswald Avery 
D)  Friedrich Miescher 
A)  Walter Flemming 
B)  Francis Crick 
C)  Oswald Avery 
D)  Friedrich Miescher

Question 17

Which is not true of the different conformations of DNA?

Accepted Answer

A)  Z-DNA is a left-handed spiral. 
B)  A-DNA and B-DNA are right-handed spirals. 
C)  A-DNA and Z-DNA segments are limited to short regions of DNA. 
D)  Both A-DNA and B-DNA are dehydrated. 
A)  Z-DNA is a left-handed spiral. 
B)  A-DNA and B-DNA are right-handed spirals. 
C)  A-DNA and Z-DNA segments are limited to short regions of DNA. 
D)  Both A-DNA and B-DNA are dehydrated.

Question 18

Deoxythymidine is a found mainly in DNA.

Accepted Answer

A)  nucleotide 
B)  eeoxynucleotide 
C)  nucleoside 
D)  deoxynucleoside 
E)  glycoside 
A)  nucleotide 
B)  eeoxynucleotide 
C)  nucleoside 
D)  deoxynucleoside 
E)  glycoside

Question 19

Which of the following is mismatched?

Accepted Answer

A)  rRNA: 80% of cellular RNA 
B)  tRNA: carry amino acids during protein synthesis 
C)  mRNA: stable RNA carrying the coded information from DNA 
D)  small RNA: catalytic with or without proteins 
A)  rRNA: 80% of cellular RNA 
B)  tRNA: carry amino acids during protein synthesis 
C)  mRNA: stable RNA carrying the coded information from DNA 
D)  small RNA: catalytic with or without proteins

Question 20

A HATS enzymes reacts with the side-chain of lysine to form the following structure: What effect will the HATS enzymes have on histones?

Accepted Answer

A)  No effect, since histones contain few lysine residues. 
B)  HATS will increase the affinity of histones for DNA. 
C)  HATS will allow for easier unravelling of histone-DNA structures. 
D)  HATS activate histones for interaction with mRNA. 
A)  No effect, since histones contain few lysine residues. 
B)  HATS will increase the affinity of histones for DNA. 
C)  HATS will allow for easier unravelling of histone-DNA structures. 
D)  HATS activate histones for interaction with mRNA.

Exam 19: Nucleic Acids

In any species, the % A + T is equal to the % G +C.

Prokaryotic DNA is organized into protein-DNA structures called nucleoids.

Which is not a biological function of RNA?

Which is not a difference between RNA and DNA?

As B-DNA is gradually heated, the absorbance at 260 nm

About how many nucleosomes could be made from a DNA strand consisting of 1000 base pairs?

Which of the following is mismatched?

All genomes are composed of RNA.

In any species, the ratio of the % A + T to the % G + C is constant.

It is easier to melt DNA richer in AT than GC because

Five different bases are found in most DNA and RNA molecules.

DNA wraps around an octamer of histones to form bead-like structures called .

It is often not possible to determine the exact sequence of large polynucleotides such as RNA and DNA.

The packaging of DNA in cells results in about a -fold reduction in length compared to the fully extended DNA fully stretched out).

Which best describes the structure of a nucleosome core particle?

Chromatin was first observed and named by .

Which is not true of the different conformations of DNA?

Deoxythymidine is a found mainly in DNA.

Which of the following is mismatched?

A HATS enzymes reacts with the side-chain of lysine to form the following structure: What effect will the HATS enzymes have on histones?

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Dna Replication, Repair, and Recombination

Transcription and Rna Processing

Protein Synthesis

Recombinant Dna Technology

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