Question 1

Which is not a ketone body?

Accepted Answer

A)  dihydroxyacetone 
B)  acetoacetate 
C)  acetone 
D)  β-hydroxybutyrate 
A)  dihydroxyacetone 
B)  acetoacetate 
C)  acetone 
D)  β-hydroxybutyrate

Question 2

Regulation of acetyl CoA-carboxylase is accomplished by

Accepted Answer

A)  inhibition by fatty acyl CoA. 
B)  activation by citrate in vitro). 
C)  inactivation by high levels of glycagon. 
D)  All of the above 
A)  inhibition by fatty acyl CoA. 
B)  activation by citrate in vitro). 
C)  inactivation by high levels of glycagon. 
D)  All of the above

Question 3

Linoleate is an essential fatty acid in mammalian diets because mammalian cells .

Accepted Answer

A)  synthesize it from arachidonate 
B)  do not use this acid for biosynthesis 
C)  can use it to synthesize eicosanoids 
D)  do not have a desaturase that acts beyond the carbon-9 position 
A)  synthesize it from arachidonate 
B)  do not use this acid for biosynthesis 
C)  can use it to synthesize eicosanoids 
D)  do not have a desaturase that acts beyond the carbon-9 position

Question 4

Cholesterol is a precursor for each of the following, except

Accepted Answer

A)  bile salts. 
B)  vitamin D. 
C)  testosterone. 
D)  vitamin C. 
A)  bile salts. 
B)  vitamin D. 
C)  testosterone. 
D)  vitamin C.

Question 5

All of the following occur during synthesis of ether lipids except

Accepted Answer

A)  esterification of an acyl group from fatty acyl CoA to dihydroxyacetone phosphate. 
B)  displacement of the fatty acid of 1-acyldihydroxyacetone phosphate by a fatty alcohol. 
C)  oxidation of the keto group of 1-acyldihydroxyacetone by NADPH. 
D)  esterification of 1-alkylglycero-3-phosphate to produce 1-alkyl-2-acylglycero-3-phosphate. 
A)  esterification of an acyl group from fatty acyl CoA to dihydroxyacetone phosphate. 
B)  displacement of the fatty acid of 1-acyldihydroxyacetone phosphate by a fatty alcohol. 
C)  oxidation of the keto group of 1-acyldihydroxyacetone by NADPH. 
D)  esterification of 1-alkylglycero-3-phosphate to produce 1-alkyl-2-acylglycero-3-phosphate.

Question 6

Which of the following does do) not occur during the fasting state?

Accepted Answer

A)  increased insulin levels 
B)  inhibition of lipolysis 
C)  an increase in the concentration of albumin-bound fatty acids in the blood 
D)  A and B only 
E)  All of the above 
A)  increased insulin levels 
B)  inhibition of lipolysis 
C)  an increase in the concentration of albumin-bound fatty acids in the blood 
D)  A and B only 
E)  All of the above

Question 7

If the carbonyl carbon of a fatty acyl CoA molecule with a C10 chain is labeled with 14C, how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA?

Accepted Answer

A)  one 
B)  two 
C)  four 
D)  five 
A)  one 
B)  two 
C)  four 
D)  five

Question 8

The first step in fatty acid synthesis is the formation of from acetyl CoA and carbon dioxide.

Accepted Answer

A)  acetyl ACP 
B)  acetoacetyl ACP 
C)  malonyl CoA 
D)  acetoacetyl CoA 
A)  acetyl ACP 
B)  acetoacetyl ACP 
C)  malonyl CoA 
D)  acetoacetyl CoA

Question 9

What is the fate of most glycerol that is released during the hydrolysis of triacylglycerols from adipocytes?

Accepted Answer

A)  It is transported to the kidneys and excreted in the urine. 
B)  It is used in the synthesis of sphingolipids. 
C)  It is converted to glucose via gluconeogenesis in the liver. 
D)  It is absorbed by the chylomicrons. 
A)  It is transported to the kidneys and excreted in the urine. 
B)  It is used in the synthesis of sphingolipids. 
C)  It is converted to glucose via gluconeogenesis in the liver. 
D)  It is absorbed by the chylomicrons.

Question 10

The enzyme for b-oxidation is trifunctional with a2b2 tertiary structure.

Accepted Answer

A) True 
 B)False

Question 11

Which enzyme is needed for the oxidation of odd-chain saturated fatty acids that is not needed for even-chain fatty acids?

Accepted Answer

A)  methylmalonyl-CoA mutase 
B)  propionyl-CoA carboxylase 
C)  methylmalonyl-CoA racemase 
D)  All of the above 
A)  methylmalonyl-CoA mutase 
B)  propionyl-CoA carboxylase 
C)  methylmalonyl-CoA racemase 
D)  All of the above

Question 12

Which dietary lipid usually contains no ester bonds?

Accepted Answer

A)  cholesterol 
B)  triacylglycerides 
C)  glycerophospholipids 
D)  None of the above, all dietary lipids are esterified 
A)  cholesterol 
B)  triacylglycerides 
C)  glycerophospholipids 
D)  None of the above, all dietary lipids are esterified

Question 13

A patient is found to have a high concentration of cholesterol in the blood and deposits of cholesterol under the skin. The patient is diagnosed with familial hypercholesterolemia. What is the likely cause of this condition?

Accepted Answer

A)  A deficiency in insulin production by the pancreas. 
B)  Insufficient chylomicron concentration in the blood. 
C)  Overproduction of lysosomal lipases. 
D)  Lack of LDL receptors on the surfaces of nonhepatic cells. 
A)  A deficiency in insulin production by the pancreas. 
B)  Insufficient chylomicron concentration in the blood. 
C)  Overproduction of lysosomal lipases. 
D)  Lack of LDL receptors on the surfaces of nonhepatic cells.

Question 14

Drugs called statins lower cholesterol levels because they .

Accepted Answer

A)  degrade HMG-CoA reductase 
B)  bind serum cholesterol 
C)  inhibit HMG-CoA reductase 
D)  bind bile salts 
A)  degrade HMG-CoA reductase 
B)  bind serum cholesterol 
C)  inhibit HMG-CoA reductase 
D)  bind bile salts

Question 15

S-adenosylmethionine methylates phosphatidylethanolamine to form phosphatidylcholine.

Accepted Answer

A) True 
 B)False

Which is not a ketone body?

Regulation of acetyl CoA-carboxylase is accomplished by

Linoleate is an essential fatty acid in mammalian diets because mammalian cells .

Cholesterol is a precursor for each of the following, except

All of the following occur during synthesis of ether lipids except

Which of the following does do) not occur during the fasting state?

If the carbonyl carbon of a fatty acyl CoA molecule with a C₁₀chain is labeled with ¹⁴C, how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA?

The first step in fatty acid synthesis is the formation of from acetyl CoA and carbon dioxide.

What is the fate of most glycerol that is released during the hydrolysis of triacylglycerols from adipocytes?

The enzyme for b-oxidation is trifunctional with a₂b₂tertiary structure.

Which enzyme is needed for the oxidation of odd-chain saturated fatty acids that is not needed for even-chain fatty acids?

Which dietary lipid usually contains no ester bonds?

A patient is found to have a high concentration of cholesterol in the blood and deposits of cholesterol under the skin. The patient is diagnosed with familial hypercholesterolemia. What is the likely cause of this condition?

Drugs called statins lower cholesterol levels because they .

S-adenosylmethionine methylates phosphatidylethanolamine to form phosphatidylcholine.

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

Dna Replication, Repair, and Recombination

Transcription and Rna Processing

Protein Synthesis

Recombinant Dna Technology

Filters

Exam 16: Lipid Metabolism

Which is not a ketone body?

Regulation of acetyl CoA-carboxylase is accomplished by

Linoleate is an essential fatty acid in mammalian diets because mammalian cells .

Cholesterol is a precursor for each of the following, except

All of the following occur during synthesis of ether lipids except

Which of the following does do) not occur during the fasting state?

If the carbonyl carbon of a fatty acyl CoA molecule with a C10 chain is labeled with 14C, how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA?

The first step in fatty acid synthesis is the formation of from acetyl CoA and carbon dioxide.

What is the fate of most glycerol that is released during the hydrolysis of triacylglycerols from adipocytes?

The enzyme for b-oxidation is trifunctional with a2b2 tertiary structure.

Which enzyme is needed for the oxidation of odd-chain saturated fatty acids that is not needed for even-chain fatty acids?

Which dietary lipid usually contains no ester bonds?

A patient is found to have a high concentration of cholesterol in the blood and deposits of cholesterol under the skin. The patient is diagnosed with familial hypercholesterolemia. What is the likely cause of this condition?

Drugs called statins lower cholesterol levels because they .

S-adenosylmethionine methylates phosphatidylethanolamine to form phosphatidylcholine.

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

Dna Replication, Repair, and Recombination

Transcription and Rna Processing

Protein Synthesis

Recombinant Dna Technology

Filters

If the carbonyl carbon of a fatty acyl CoA molecule with a C₁₀chain is labeled with ¹⁴C, how many rounds of β-oxidation are required to produce a radioactively labeled acetyl CoA?

The enzyme for b-oxidation is trifunctional with a₂b₂tertiary structure.