Exam 14: Electron Transport and Oxidative Phosphorylation

At one time the uncoupler 2,4-dinitrophenol was used as a weight reducing drug. Its side-effects, including death, resulted in its discontinued use. How could this drug cause weight loss?

Rotation of the subunit of ATP synthase causes conformational changes in the catalytic sites that produce ATP.

Which component of ATP synthase is the site of the proton channel?

In mammals the enzyme complexes of oxidative phosphorylation are in the inner mitochondrial matrix.

A lipid-soluble cofactor that can diffuse freely in the membrane of the electron transport chain and carry electrons across the membrane is .

The chemiosmotic theory explains that the energy for driving ATP formation in mitochondria comes from a proton concentration gradient.

White blood cells in mammals can produce toxic superoxide ions to kill bacterial cells.

The ultimate electron acceptor from complex II is .

ATP directly provides the energy to transport protons across the inner membrane from the matrix to the inner-membrane space of mitochondria.

E. coli can use electron carriers to grow aerobically or anaerobically.

Which statement is true about two reactions that are coupled?

Mitochondrial electron transport and ATP formation are interdependent.

The enzyme complexes I-IV in the electron transport chain associate with each other by a combination of hydrophobic interactions, disulfide bridges and hydrogen bonding.

In a series of oxidation-reduction agents, the strongest, weakest) reducing agent has the highest, lowest) reduction potential.

Which is not a component of complex II?

Complex II participates in both the electron transport chain and the citric acid cycle.

Which statement is not true about the transport of ATP across the inner mitochondrial membrane on its way to the cytosol?

Which is a component of complex I?

Compare the pH of the mitochondrial matrix and the inner membrane space.

The is between the inner and outer membranes of the mitochondria.