Question 1

Which of the following is not regulated in glycolysis?

Accepted Answer

A)  pyruvate kinase 
B)  phosphoglycerate kinase 
C)  hexokinase 
D)  PFK-1 
A)  pyruvate kinase 
B)  phosphoglycerate kinase 
C)  hexokinase 
D)  PFK-1

Question 2

Arsenite

Accepted Answer

A)  poisons by the same mechanism as arsenate. 
B)  is less toxic than arsenate. 
C)  binds tightly to lipoamide sulfur atoms. 
D)  None of the above 
A)  poisons by the same mechanism as arsenate. 
B)  is less toxic than arsenate. 
C)  binds tightly to lipoamide sulfur atoms. 
D)  None of the above

Question 3

Triose phosphate isomerase is diffusion controlled.

Accepted Answer

A) True 
 B)False

Question 4

In glycolysis, there is a net yield of two molecules of ATP per molecule of glucose.

Accepted Answer

A) True 
 B)False

Question 5

Enzymes that catalyze the same reaction are called .

Accepted Answer

A)  isozymes 
B)  complementary enzymes 
C)  cofactors 
D)  catalytes 
A)  isozymes 
B)  complementary enzymes 
C)  cofactors 
D)  catalytes

Question 6

Which applies to fructose 1,6-bisphosphate?

Accepted Answer

A)  inhibitor of pyruvate kinase 
B)  product of PFK-1 catalyzed step in glycolysis 
C)  isomer of glucose 1,6-bisphosphate 
D)  All of the above 
A)  inhibitor of pyruvate kinase 
B)  product of PFK-1 catalyzed step in glycolysis 
C)  isomer of glucose 1,6-bisphosphate 
D)  All of the above

Question 7

Cells that form ATP mainly by glycolysis are

Accepted Answer

A)  anaerobic yeasts. 
B)  lactic acid bacteria. 
C)  kidney medulla cells. 
D)  A and B 
E)  A, B and C 
A)  anaerobic yeasts. 
B)  lactic acid bacteria. 
C)  kidney medulla cells. 
D)  A and B 
E)  A, B and C

Question 8

Two molecules of ATP are consumed per glucose molecule during the hexose stage of glycolysis.

Accepted Answer

A) True 
 B)False

Question 9

Compared to pyruvate, the carbon atoms in lactate .

Accepted Answer

A)  are more reduced 
B)  are more oxidized 
C)  are equally as oxidized 
D)  carry more charge 
A)  are more reduced 
B)  are more oxidized 
C)  are equally as oxidized 
D)  carry more charge

Question 10

Four molecules of ATP are consumed per glucose during the hexose stage of glycolysis.

Accepted Answer

A) True 
 B)False

Question 11

Under what situation might lactic acidosis occur?

Accepted Answer

A)  Lactate dehydrogenase is inactive. 
B)  Transport of glucose into cells is accelerated. 
C)  Oxygen supply to tissues is inadequate. 
D)  PFK-1 is over-activated. 
A)  Lactate dehydrogenase is inactive. 
B)  Transport of glucose into cells is accelerated. 
C)  Oxygen supply to tissues is inadequate. 
D)  PFK-1 is over-activated.

Question 12

How many ATP molecules are consumed in glycolysis for every one molecule of glucose?

Accepted Answer

A)  0; ATP is produced, not consumed, by glycolysis 
B)  1 
C)  2 
D)  3 
E)  4 
A)  0; ATP is produced, not consumed, by glycolysis 
B)  1 
C)  2 
D)  3 
E)  4

Question 13

Two molecules of ATP are produced per glucose during the hexose stage of glycolysis.

Accepted Answer

A) True 
 B)False

Question 14

Glucose is the only hexose which can enter the glycolytic pathway.

Accepted Answer

A) True 
 B)False

Question 15

Mammals can convert pyruvate to either ethanol or lactate depending on the availability of oxygen.

Accepted Answer

A) True 
 B)False

Question 16

Glycolysis occurs in the cytosol of eukaryotes.

Accepted Answer

A) True 
 B)False

Question 17

The reaction catalyzed by PFK-1 is metabolically reversible.

Accepted Answer

A) True 
 B)False

Question 18

Hamsters love to run on exercise wheels. Prolonged running at a high rate of speed requires ATP. Could a hamster with a defective gene for the enzyme lactate dehydrogenase meet the extra ATP demand for prolonged, fast wheel-running by maintaining a high rate of glycolysis? Why or why not?

Accepted Answer

A)  No, not enough NAD+ can be regenerated for glycolysis to continue at a high rate. 
B)  No, the defective gene will cause a rapid decline in pH in the muscles used for running. 
C)  Yes, the defective enzyme has no effect on the glycolytic pathway. 
D)  Yes, the enzyme alcohol dehydrogenase will supply the needed NAD+ if the lactose dehydrogenase cannot. 
A)  No, not enough NAD+ can be regenerated for glycolysis to continue at a high rate. 
B)  No, the defective gene will cause a rapid decline in pH in the muscles used for running. 
C)  Yes, the defective enzyme has no effect on the glycolytic pathway. 
D)  Yes, the enzyme alcohol dehydrogenase will supply the needed NAD+ if the lactose dehydrogenase cannot.

Question 19

The overall △G for glycolysis is -72 kJ/mol in erythrocytes. Which statement below is true?

Accepted Answer

A)  The value of △G0ʹ is also -72 kJ/mol since the cytosol pH is close to 7. 
B)  The free energy of glycolysis is found as the sum of the standard free energy changes for the individual pathway reactions. 
C)  The negative sign of △G shows that this pathway will proceed toward product pyruvate) under normal cellular conditions. 
D)  All of the above 
A)  The value of △G0ʹ is also -72 kJ/mol since the cytosol pH is close to 7. 
B)  The free energy of glycolysis is found as the sum of the standard free energy changes for the individual pathway reactions. 
C)  The negative sign of △G shows that this pathway will proceed toward product pyruvate) under normal cellular conditions. 
D)  All of the above

Question 20

Transfer of a high-energy phosphoryl group to ADP, resulting in ATP occurs when:

Accepted Answer

A)  1,3-bisphosphoglycerate → 3-phosphoglycerate 
B)  phosphoenolpyruvate PEP) → pyruvate 
C)  3-phosphoglycerate → 2-phosphoglycerate 
D)  Both A and B 
E)  None of the above 
A)  1,3-bisphosphoglycerate → 3-phosphoglycerate 
B)  phosphoenolpyruvate PEP) → pyruvate 
C)  3-phosphoglycerate → 2-phosphoglycerate 
D)  Both A and B 
E)  None of the above

Exam 11: Glycolysis

Which of the following is not regulated in glycolysis?

Arsenite

Triose phosphate isomerase is diffusion controlled.

In glycolysis, there is a net yield of two molecules of ATP per molecule of glucose.

Enzymes that catalyze the same reaction are called .

Which applies to fructose 1,6-bisphosphate?

Cells that form ATP mainly by glycolysis are

Two molecules of ATP are consumed per glucose molecule during the hexose stage of glycolysis.

Compared to pyruvate, the carbon atoms in lactate .

Four molecules of ATP are consumed per glucose during the hexose stage of glycolysis.

Under what situation might lactic acidosis occur?

How many ATP molecules are consumed in glycolysis for every one molecule of glucose?

Two molecules of ATP are produced per glucose during the hexose stage of glycolysis.

Glucose is the only hexose which can enter the glycolytic pathway.

Mammals can convert pyruvate to either ethanol or lactate depending on the availability of oxygen.

Glycolysis occurs in the cytosol of eukaryotes.

The reaction catalyzed by PFK-1 is metabolically reversible.

Hamsters love to run on exercise wheels. Prolonged running at a high rate of speed requires ATP. Could a hamster with a defective gene for the enzyme lactate dehydrogenase meet the extra ATP demand for prolonged, fast wheel-running by maintaining a high rate of glycolysis? Why or why not?

The overall △G for glycolysis is -72 kJ/mol in erythrocytes. Which statement below is true?

Transfer of a high-energy phosphoryl group to ADP, resulting in ATP occurs when:

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Coenzymes and Vitamins

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

Dna Replication, Repair, and Recombination

Transcription and Rna Processing

Protein Synthesis

Recombinant Dna Technology

Filters