Question 1

Match each of the following vitamins with an associate nutritional deficiency disease.  
-Folate

Accepted Answer

The answer of Match each of the following vitamins with...

Question 2

Which are common protein coenzymes?

Accepted Answer

A)  cytochromes 
B)  phylloquinones 
C)  tetrahydrofolates 
D)  α-tocopherols 
A)  cytochromes 
B)  phylloquinones 
C)  tetrahydrofolates 
D)  α-tocopherols

Question 3

Which vitamin is shown below?

Accepted Answer

A)  vitamin C 
B)  thiamin vitamin B1) 
C)  cobalamin vitamin B12) 
D)  folate 
A)  vitamin C 
B)  thiamin vitamin B1) 
C)  cobalamin vitamin B12) 
D)  folate

Question 4

Minerals which are cofactors may be reversibly bound and are then usually directly involved in catalytic reactions.

Accepted Answer

A) True 
 B)False

Question 5

Match each of the following vitamins with an associate nutritional deficiency disease.  
-Ascorbate

Accepted Answer

The answer of Match each of the following vitamins with...

Question 6

Structures of several dehydrogenases indicate that many possess one or more similar NAD or NADP-binding structures consisting of babab units in Rossman folds.

Accepted Answer

A) True 
 B)False

Question 7

Which statement is false about 5,6,7,8-tetrahydrobiopterin?

Accepted Answer

A)  It is required by the enzyme that catalyzes the synthesis of nitric oxide from arginine. 
B)  It is synthesized by animals and other organisms. 
C)  It is used in the transfer of phosphate groups during DNA synthesis. 
D)  It is a reducing agent in the conversion of phenylalanine to tyrosine. 
A)  It is required by the enzyme that catalyzes the synthesis of nitric oxide from arginine. 
B)  It is synthesized by animals and other organisms. 
C)  It is used in the transfer of phosphate groups during DNA synthesis. 
D)  It is a reducing agent in the conversion of phenylalanine to tyrosine.

Question 8

Protein catalysts rely exclusively on the amino acid residues for reactivity at the sites of action.

Accepted Answer

A) True 
 B)False

Question 9

Cobalamin is synthesized by most organisms from simple precursors and does not need to be in the diet.

Accepted Answer

A) True 
 B)False

Question 10

Another name for α-tocopherol is vitamin .

Accepted Answer

A)  A 
B)  B12  
C)  C 
D)  D 
E)  E 
A)  A 
B)  B12  
C)  C 
D)  D 
E)  E

Question 11

What kind of reaction is most important for the reactive center of lipoamide?

Accepted Answer

A)  oxidation of a carbonyl group 
B)  reduction of a disulfide bond 
C)  formation of a Schiff base 
D)  a cis-trans configurational change about a disulfide bond 
A)  oxidation of a carbonyl group 
B)  reduction of a disulfide bond 
C)  formation of a Schiff base 
D)  a cis-trans configurational change about a disulfide bond

Question 12

Which type of atom is involved in the reactive center of lipoamide?

Accepted Answer

A)  sulfur 
B)  nitrogen 
C)  phosphorous 
D)  oxygen 
A)  sulfur 
B)  nitrogen 
C)  phosphorous 
D)  oxygen

Question 13

Which amino acid can form a covalent bond to the coenzyme pyridoxal phosphate?

Accepted Answer

A)  aspartate 
B)  cysteine 
C)  lysine 
D)  serine 
A)  aspartate 
B)  cysteine 
C)  lysine 
D)  serine

Question 14

The role of zinc in the mechanisms of carbonic anhydrase is to

Accepted Answer

A)  maintain the configuration of the holoenzyme. 
B)  bind to three histidine residues. 
C)  produce a nucleophilic attack on the substrate. 
D)  promote ionization of bound water. 
E)  produce an electrophilic attack on the substrate. 
A)  maintain the configuration of the holoenzyme. 
B)  bind to three histidine residues. 
C)  produce a nucleophilic attack on the substrate. 
D)  promote ionization of bound water. 
E)  produce an electrophilic attack on the substrate.

Question 15

The structure shown below is which coenzyme?

Accepted Answer

A)  QH2  
B)  Vitamin B12 
C)  Biotin 
D)  Thiamine pyrophosphate 
A)  QH2  
B)  Vitamin B12 
C)  Biotin 
D)  Thiamine pyrophosphate

Question 16

What is the role of the magnesium ion in kinases that require the magnesium-ATP complex to donate phosphoryl groups?

Accepted Answer

A)  maintain the configuration of the holoenzyme 
B)  shield the charged phosphate groups of ATP 
C)  produce an electrophilic attack on the substrate 
D)  promote ionization of bound water 
E)  produce ionization of the substrate to be phosphorylated 
A)  maintain the configuration of the holoenzyme 
B)  shield the charged phosphate groups of ATP 
C)  produce an electrophilic attack on the substrate 
D)  promote ionization of bound water 
E)  produce ionization of the substrate to be phosphorylated

Question 17

Ca++ or Mg++ are most likely to be part of , while Zn++ or Fe++ are present in .

Accepted Answer

A)  metal-activated enzymes; metalloenzymes 
B)  metalloenzymes; metal-activated enzymes 
C)  cofactors; coenzymes 
D)  coenzymes; cofactors 
E)  apoenzymes; holoenzymes 
A)  metal-activated enzymes; metalloenzymes 
B)  metalloenzymes; metal-activated enzymes 
C)  cofactors; coenzymes 
D)  coenzymes; cofactors 
E)  apoenzymes; holoenzymes

Question 18

An internal aldimine forms when PLP is covalently bound to its enzyme.

Accepted Answer

A) True 
 B)False

Question 19

Match each of the following vitamins with an associate nutritional deficiency disease.  
-Thiamine B1)

Accepted Answer

Question 20

NAD and NADP dependent dehydrogenases catalyze substrates by transferring to C-4 of NAD+ and NADP+.

Accepted Answer

A)  one electron 
B)  two electrons 
C)  one electron and one proton 
D)  two electrons and one proton 
E)  two electrons and two protons 
A)  one electron 
B)  two electrons 
C)  one electron and one proton 
D)  two electrons and one proton 
E)  two electrons and two protons

Exam 7: Coenzymes and Vitamins

Match each of the following vitamins with an associate nutritional deficiency disease. -Folate

Which are common protein coenzymes?

Which vitamin is shown below?

Minerals which are cofactors may be reversibly bound and are then usually directly involved in catalytic reactions.

Match each of the following vitamins with an associate nutritional deficiency disease. -Ascorbate

Structures of several dehydrogenases indicate that many possess one or more similar NAD or NADP-binding structures consisting of babab units in Rossman folds.

Which statement is false about 5,6,7,8-tetrahydrobiopterin?

Protein catalysts rely exclusively on the amino acid residues for reactivity at the sites of action.

Cobalamin is synthesized by most organisms from simple precursors and does not need to be in the diet.

Another name for α-tocopherol is vitamin .

What kind of reaction is most important for the reactive center of lipoamide?

Which type of atom is involved in the reactive center of lipoamide?

Which amino acid can form a covalent bond to the coenzyme pyridoxal phosphate?

The role of zinc in the mechanisms of carbonic anhydrase is to

The structure shown below is which coenzyme?

What is the role of the magnesium ion in kinases that require the magnesium-ATP complex to donate phosphoryl groups?

Ca++ or Mg++ are most likely to be part of , while Zn++ or Fe++ are present in .

An internal aldimine forms when PLP is covalently bound to its enzyme.

Match each of the following vitamins with an associate nutritional deficiency disease. -Thiamine B1)

NAD and NADP dependent dehydrogenases catalyze substrates by transferring to C-4 of NAD+ and NADP+.

Introduction to Biochemistry

Water

Amino Acids and the Primary Structures of Proteins

Proteins: Three-Dimensional Structure and Function

Properties of Enzymes

Mechanisms of Enzymes

Carbohydrates

Lipids and Membranes

Introduction to Metabolism

Glycolysis

Gluconeogenesis, the Pentose Phosphate Pathway, and Glycogen Metabolism

The Citric Acid Cycle

Electron Transport and Oxidative Phosphorylation

Photosynthesis

Lipid Metabolism

Amino Acid Metabolism

Nucleotide Metabolism

Nucleic Acids

Dna Replication, Repair, and Recombination

Transcription and Rna Processing

Protein Synthesis

Recombinant Dna Technology

Filters

Ca⁺⁺or Mg⁺⁺are most likely to be part of , while Zn⁺⁺or Fe⁺⁺are present in .

Match each of the following vitamins with an associate nutritional deficiency disease. -Thiamine B₁)

NAD and NADP dependent dehydrogenases catalyze substrates by transferring to C-4 of NAD⁺and NADP⁺.