Question 1

Which of the following is true of tRNA processing in

Accepted Answer

A)  RNaseP acts as an endonuclease 
B)  The recognition sequence of RNaseD is 3'CCA5' 
C)  RNAseD acts as an endonuclease 
D)  More than one of the answers 
E)  coli? 
A)  RNaseP acts as an endonuclease 
B)  The recognition sequence of RNaseD is 3'CCA5' 
C)  RNAseD acts as an endonuclease 
D)  More than one of the answers 
E)  coli? A

Question 2

Which of the following is not an example of a eukaryotic regulatory element?

Accepted Answer

A)  Enhancers 
B)  Silencers 
C)  Core promoters 
D)  Cis-acting elements 
E)  All of the answers are examples 
A)  Enhancers 
B)  Silencers 
C)  Core promoters 
D)  Cis-acting elements 
E)  All of the answers are examples E

Question 3

cDNA contains introns

Accepted Answer

A)  True 
B)  False 
C)  It varies from cDNA to cDNA 
A)  True 
B)  False 
C)  It varies from cDNA to cDNA B

Question 4

How many basal transcription factors are there?

Accepted Answer

A)  3 
B)  4 
C)  5 
D)  6 
A)  3 
B)  4 
C)  5 
D)  6

Question 5

What is the purpose of phosphorylating the carboxy terminal domain (CTD)?

Accepted Answer

A)  Convert from initiation to the elongation stage 
B)  To aid in transcriptional initiation 
C)  Phosphorylate transcription factors 
D)  More than one above 
A)  Convert from initiation to the elongation stage 
B)  To aid in transcriptional initiation 
C)  Phosphorylate transcription factors 
D)  More than one above

Question 6

What enables the splicing of group I and II introns?

Accepted Answer

A)  Spliceosomes 
B)  Ribozymes 
C)  snRNA 
D)  Poly-A tail 
A)  Spliceosomes 
B)  Ribozymes 
C)  snRNA 
D)  Poly-A tail

Question 7

Most eukaryotic genes are collinear.

Accepted Answer

A)  True 
B)  False 
C)  It is unknown at this time 
A)  True 
B)  False 
C)  It is unknown at this time

Question 8

Which of the following is not part of the basal transcription apparatus?

Accepted Answer

A)  DNA 
B)  TFIID 
C)  RNA polymerase II 
D)  Mediator 
E)  TFIIB 
A)  DNA 
B)  TFIID 
C)  RNA polymerase II 
D)  Mediator 
E)  TFIIB

Question 9

The Prinbow box contains a CACAAC consensus sequence located in the -100 region of the promoter.

Accepted Answer

A) True 
 B)False

Question 10

Alternative splicing allows an organism to .

Accepted Answer

A)  Carry fewer genes 
B)  Carry more genes 
C)  Produce fewer gene products 
D)  More than one of the answers 
A)  Carry fewer genes 
B)  Carry more genes 
C)  Produce fewer gene products 
D)  More than one of the answers

Question 11

Following transcription, the RNA has a complementary sequence of which of the following?

Accepted Answer

A)  Regulatory sequences 
B)  Termination sequences 
C)  The coding strand of DNA 
D)  The template strand of DNA 
E)  None of the answers are correct 
A)  Regulatory sequences 
B)  Termination sequences 
C)  The coding strand of DNA 
D)  The template strand of DNA 
E)  None of the answers are correct

Question 12

Basal transcription in eukaryotes involves the action of only the core promoter.

Accepted Answer

A) True 
 B)False

Question 13

The mRNA is read in groups of nucleotides called quadrons.

Accepted Answer

A) True 
 B)False

Question 14

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

Accepted Answer

A)  TFIIB 
B)  TFIID 
C)  TFIIE 
D)  TFIIH 
E)  TFIIF 
A)  TFIIB 
B)  TFIID 
C)  TFIIE 
D)  TFIIH 
E)  TFIIF

Question 15

What would be the effect on in vitro transcription if you replaced the entire TFIID protein with the single subunit TBP?

Accepted Answer

A)  Transcription could not be terminated 
B)  The initiation complex could not form 
C)  RNA polymerase II would never be recruited to carry out elongation 
D)  There would be no effect 
A)  Transcription could not be terminated 
B)  The initiation complex could not form 
C)  RNA polymerase II would never be recruited to carry out elongation 
D)  There would be no effect

Question 16

A functional protein would contain the information contained within which of the following regions of DNA?

Accepted Answer

A)  Exons 
B)  Introns 
C)  Enhancers 
D)  Promoters 
E)  All of the answers are correct 
A)  Exons 
B)  Introns 
C)  Enhancers 
D)  Promoters 
E)  All of the answers are correct

Question 17

What is the catalytic subunit of prokaryotic RNA polymerase?

Accepted Answer

A)  a 
B)  b 
C)  b' 
D)  σ 
E)  More than one of the answers 
A)  a 
B)  b 
C)  b' 
D)  σ 
E)  More than one of the answers

Question 18

The RNA polymerase forms a closed complex during the process of elongation during transcription.

Accepted Answer

A) True 
 B)False

Question 19

What basal transcription factor is a helicase?

Accepted Answer

A)  TFIID 
B)  TFIIH 
C)  TFIIF 
D)  TFIIB 
A)  TFIID 
B)  TFIIH 
C)  TFIIF 
D)  TFIIB

Question 20

Which of the following processes is important for the initiation of translation?

Accepted Answer

A)  Alternative splicing 
B)  RNA editing 
C)  5' capping 
D)  3' polyA tailing 
E)  Trimming 
A)  Alternative splicing 
B)  RNA editing 
C)  5' capping 
D)  3' polyA tailing 
E)  Trimming

Exam 12: Gene Transcription and Rna Modification

Which of the following is true of tRNA processing in

Which of the following is not an example of a eukaryotic regulatory element?

cDNA contains introns

How many basal transcription factors are there?

What is the purpose of phosphorylating the carboxy terminal domain (CTD)?

What enables the splicing of group I and II introns?

Most eukaryotic genes are collinear.

Which of the following is not part of the basal transcription apparatus?

The Prinbow box contains a CACAAC consensus sequence located in the -100 region of the promoter.

Alternative splicing allows an organism to .

Following transcription, the RNA has a complementary sequence of which of the following?

Basal transcription in eukaryotes involves the action of only the core promoter.

The mRNA is read in groups of nucleotides called quadrons.

A mutation in which of the following would result in a failure of the RNA polymerase to maintain an open complex?

What would be the effect on in vitro transcription if you replaced the entire TFIID protein with the single subunit TBP?

A functional protein would contain the information contained within which of the following regions of DNA?

What is the catalytic subunit of prokaryotic RNA polymerase?

The RNA polymerase forms a closed complex during the process of elongation during transcription.

What basal transcription factor is a helicase?

Which of the following processes is important for the initiation of translation?

Overview of Genetics

Mendelian Inheritance

Reproduction and Chromosome Transmission

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Translation of Mrna

Gene Regulation in Bacteria and Bacteriophages

Gene Regulation in Eukaryotes

Gene Mutation and Dna Repair

Recombination and Transposition at the Molecular

Recombinant Dna Technology

Biotechnology

Genomics I: Analysis of Dna

Genomics II: Functional Genomics, Proteomics, and

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

Evolutionary Genetics

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