Question 1

Site-specific recombination occurs between homologous sequences of DNA.
FALSE

Accepted Answer

A) True 
 B)False  False

Question 2

Chromosomes that are genetically the same, but have different banding patterns using Hoechst 33258
and Giemsa stains, are called giemequin chromosomes.

Accepted Answer

A) True 
 B)False  False

Question 3

Transposable elements in bacteria are commonly called insertion sequences.

Accepted Answer

A) True 
 B)False  True

Question 4

Which of the following may account for the process of gene conversion?

Accepted Answer

A)  DNA mismatch repair 
B)  DNA gap repair 
C)  Photolyase activity 
D)  Nucleotide excision repair 
E)  More than one of the above 
A)  DNA mismatch repair 
B)  DNA gap repair 
C)  Photolyase activity 
D)  Nucleotide excision repair 
E)  More than one of the above

Question 5

Long-terminal repeats are unique to which group of transposons?

Accepted Answer

A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence 
A)  Composite transposon 
B)  Non-viral retro element 
C)  Viral-like retro element 
D)  Replicative transposon 
E)  Insertion sequence

Question 6

Transposon tagging may be used for which of the following reasons?

Accepted Answer

A)  To test if a transposon is replicative 
B)  As a tool to clone novel genes 
C)  To track the movement of transposons between species 
D)  To inactivate transposons in a genome 
A)  To test if a transposon is replicative 
B)  As a tool to clone novel genes 
C)  To track the movement of transposons between species 
D)  To inactivate transposons in a genome

Question 7

Which of the following domain types is unique to the heavy chain of the polypeptide?

Accepted Answer

A)  V 
B)  D 
C)  J 
D)  C 
E)  None of the answers are correct 
A)  V 
B)  D 
C)  J 
D)  C 
E)  None of the answers are correct

Question 8

In the Perry-Wolff experiments with harlequin chromosomes, colcemid was applied to the cells following labeling with BrdU for what reason?

Accepted Answer

A)  To enhance the rate of recombination between chromatids 
B)  To reduce the rate of recombination between chromatids 
C)  To separate the chromosomes 
D)  As a stain 
E)  To stop the cells from completing mitosis 
A)  To enhance the rate of recombination between chromatids 
B)  To reduce the rate of recombination between chromatids 
C)  To separate the chromosomes 
D)  As a stain 
E)  To stop the cells from completing mitosis

Question 9

Which of the following is an example of a transposable element?

Accepted Answer

A)  Alu in Homo sapiens 
B)  P elements in Drosophila 
C)  Mu in bacteria 
D)  Ty in yeast 
E)  All of the answers are correct 
A)  Alu in Homo sapiens 
B)  P elements in Drosophila 
C)  Mu in bacteria 
D)  Ty in yeast 
E)  All of the answers are correct

Question 10

Alu is an example of a retro element in the human genome.

Accepted Answer

A) True 
 B)False

Question 11

The type of transposition in which the number of transposons increases in the genome is called .

Accepted Answer

A)  Replicative transposition 
B)  Simple transposition 
C)  Site-specific transposition 
D)  Complex transposition 
A)  Replicative transposition 
B)  Simple transposition 
C)  Site-specific transposition 
D)  Complex transposition

Question 12

Bacteriophage l inserts into a bacterial chromosome using which of the following?

Accepted Answer

A)  Nucleotide excision repair 
B)  Endonuclease activity 
C)  Site-specific recombination 
D)  DNA gap repair 
E)  None of the answers are correct 
A)  Nucleotide excision repair 
B)  Endonuclease activity 
C)  Site-specific recombination 
D)  DNA gap repair 
E)  None of the answers are correct

Question 13

The Holliday model is used to explain which of the following?

Accepted Answer

A)  Recombination between homologous chromosomes 
B)  Recombination between sister chromatids 
C)  The creation of harlequin chromosomes 
D)  The action of transposons 
E)  None of the answers are correct 
A)  Recombination between homologous chromosomes 
B)  Recombination between sister chromatids 
C)  The creation of harlequin chromosomes 
D)  The action of transposons 
E)  None of the answers are correct

Question 14

Which enzyme is unique to the retro elements?

Accepted Answer

A)  Reverse transcriptase 
B)  Reverse resolvase 
C)  Transposase 
D)  Integrase 
E)  Reverse integrase 
A)  Reverse transcriptase 
B)  Reverse resolvase 
C)  Transposase 
D)  Integrase 
E)  Reverse integrase

Question 15

Which of the following is technically not part of the genetic information of a transposable element?

Accepted Answer

A)  Long-terminal repeats 
B)  Inverted repeats 
C)  Direct repeats 
D)  Transposase 
E)  All of the answers are correct 
A)  Long-terminal repeats 
B)  Inverted repeats 
C)  Direct repeats 
D)  Transposase 
E)  All of the answers are correct

Question 16

The process of recombination occurs during metaphase I of meiosis.

Accepted Answer

A) True 
 B)False

Question 17

LINEs and SINEs may be due to high levels of transposable element activity.

Accepted Answer

A) True 
 B)False

Question 18

A heteroduplex is a DNA double helix that contains mismatches.

Accepted Answer

A) True 
 B)False

Question 19

A incomplete transposon contains all of the information necessary to conduct transposition.

Accepted Answer

A) True 
 B)False

Question 20

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Accepted Answer

A)  A nick in only one strand of the DNA 
B)  The double-stranded break model 
C)  DNA gap repair synthesis 
D)  Heteroduplex formation 
A)  A nick in only one strand of the DNA 
B)  The double-stranded break model 
C)  DNA gap repair synthesis 
D)  Heteroduplex formation

Exam 17: Recombination and Transposition at the Molecular

Site-specific recombination occurs between homologous sequences of DNA. FALSE

Chromosomes that are genetically the same, but have different banding patterns using Hoechst 33258 and Giemsa stains, are called giemequin chromosomes.

Transposable elements in bacteria are commonly called insertion sequences.

Which of the following may account for the process of gene conversion?

Long-terminal repeats are unique to which group of transposons?

Transposon tagging may be used for which of the following reasons?

Which of the following domain types is unique to the heavy chain of the polypeptide?

In the Perry-Wolff experiments with harlequin chromosomes, colcemid was applied to the cells following labeling with BrdU for what reason?

Which of the following is an example of a transposable element?

Alu is an example of a retro element in the human genome.

The type of transposition in which the number of transposons increases in the genome is called .

Bacteriophage l inserts into a bacterial chromosome using which of the following?

The Holliday model is used to explain which of the following?

Which enzyme is unique to the retro elements?

Which of the following is technically not part of the genetic information of a transposable element?

The process of recombination occurs during metaphase I of meiosis.

LINEs and SINEs may be due to high levels of transposable element activity.

A heteroduplex is a DNA double helix that contains mismatches.

A incomplete transposon contains all of the information necessary to conduct transposition.

Which of the following most likely accounts for the majority of the recombination events during both DNA repair and meiosis?

Overview of Genetics

Mendelian Inheritance

Reproduction and Chromosome Transmission

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria and

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria and Bacteriophages

Gene Regulation in Eukaryotes

Gene Mutation and Dna Repair

Recombinant Dna Technology

Biotechnology

Genomics I: Analysis of Dna

Genomics II: Functional Genomics, Proteomics, and

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Quantitative Genetics

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