Exam 3: Pharmacokinetics, Pharmacodynamics, and Pharmacogenetics

The nurse gives 800 mg of a drug that has a half-life of 8 hours. How much drug will be left in the body in 24 hours if no additional drug is given?

The provider has ordered amoxicillin with clavulanate (Augmentin) for a child who has otitis media. The child's parent asks why this drug is necessary when amoxicillin is less expensive. The nurse will explain that clavulanate is added to amoxicillin because it:

Which drug will go through a disintegration process after it is administered?

The nurse is preparing to administer a drug and learns that it is 90% protein bound. The patient's serum albumin level is low. The nurse will observe the patient for:

The nurse is teaching a patient who will begin taking ciprofloxacin. What instruction will the nurse include when teaching this patient about this drug?

The nurse is preparing to administer a drug that is ordered to be given twice daily. The nurse reviews the medication information and learns that the drug has a half-life of 24 hours. What will the nurse do next?

A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be given by subcutaneous injection instead of by mouth. The nurse will explain that this is because

The nurse is teaching a patient about a drug that causes photosensitivity. Which statement by the patient indicates a need for further teaching?

The nurse is preparing to administer an oral medication that is water soluble. The nurse understands that this drug:

The nurse is preparing to administer furosemide to a patient who takes digoxin. The nurse will plan to monitor the patient for:

A patient asks the nurse about using OTC medications. The nurse will tell the patient that OTC medications:

The nurse is preparing to administer two IV medications that should not be given using the same IV tubing. The nurse understands that this is because of drug:

A patient has been taking a drug for several years and tells the nurse it is no longer working. The nurse learns that the patient has recently begun taking an over-the-counter (OTC) antacid medication. What does the nurse suspect is occurring?

The community health nurse is teaching a group of elderly residents in an assisted care facility about medication use. The nurse will remind the residents that OTC medications:

A patient will receive penicillin to treat an infection. The provider orders probenecid (Probalan), a medication to treat gout, even though the patient does not have gout. Which action by the nurse is correct?

A patient who takes the anticoagulant warfarin will begin taking the anticonvulsant drug carbamazepine. The nurse reviews the drug information for these drugs and learns that carbamazepine is a hepatic enzyme inducer. The nurse anticipates that which of the following may be required?

If a drug has a half-life of 12 hours and is given twice daily starting at 0800 on a Monday, when will a steady state be achieved?

The nurse assesses a patient who is receiving morphine sulfate intravenously using a patient-controlled analgesia pump. The nurse notes somnolence and respiratory depression, which are signs of morphine toxicity. The nurse will prepare to administer naloxone (Narcan) because it:

Which patients are at particularly high risk for drug interactions? (Select all that apply.)

A patient who takes a drug that undergoes gastric absorption will begin taking an opioid analgesic after sustaining an injury in a motor vehicle accident. The nurse will observe the patient closely for which effects?