Exam 4: Pharmacogenetics

The physician has ordered UGT1A1 gene testing for a patient with colon cancer. The nurse recognizes that which of the following drugs can result in severe diarrhea and neutropenia in persons with a specific UGT1A1 gene variant?

Which of the following best describes pharmacogenetics?

A patient is diagnosed with Stevens-Johnson syndrome and the provider thinks this is related to an HLA B*1502 variant that resulted in drug toxicity. The nurse would know that which of the following medications is likely to blame:

Gregor Mendel is known for which of the following?

The labeling for clopidogrel discusses pharmacogenomic testing for genetic variation in which of the following?

The Genetic Information Nondiscrimination Act (GINA) was enacted to:

Codeine and tramadol are prodrugs that require metabolism by which enzyme prior to providing analgesic relief?

The FDA recommends genetic testing of which of the following for patients prior to initiating abacavir due to a risk of potentially fatal multiorgan hypersensitivity in 6-10% of users?

There are many legal and ethical issues related to pharmacogenomics. Which of the following are questions not related to privacy?