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Phosphorylation of Signaling Proteins Can Have Activating or Inhibitory Effects

Question 30

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Phosphorylation of signaling proteins can have activating or inhibitory effects on protein function. In many cases, such as the activation of mTOR, the phosphorylation of an inhibitory protein leads to inactivation of the inhibitor, resulting in downstream signaling. T-cell receptor signaling leads to enhanced integrin-mediated cell adhesion

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