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A Specific Recessive X-Linked Mutation Prevents the Formation of Sweat

Question 178

Multiple Choice

A specific recessive X-linked mutation prevents the formation of sweat glands within the skin.  Individuals heterozygous for this mutation exhibit a mosaic phenotype, with some patches of skin lacking sweat glands and other patches containing a normal distribution of sweat glands.  Which of the following statements best explains the genetic mechanism underlying this mosaic phenotype in heterozygous individuals?


A) Expression of Y chromosome genes masks expression of the mutant gene.
B) Genes on paternally inherited X chromosomes are silenced.
C) All mutant genes on the X chromosome are not expressed.
D) One X chromosome is inactivated at random in embryonic cells during development.

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