Question 1

Select the phage λ proteins that function as antiterminators (check all that apply).

Accepted Answer

A)  cII 
B)  N 
C)  Q 
D)  cro 
A)  cII 
B)  N 
C)  Q 
D)  cro

Question 2

The reverse transcription of HIV RNA utilizes host cell tRNA as a primer. Specifically, a tRNA for lysine is utilized. Would a drug that blocked the host cell synthesis of the tRNA for lysine be a good drug to prevent the HIV life cycle?

Accepted Answer

A)  Yes, it should stop the reverse transcription of the HIV genome with few side effects. 
B)  No, the virus would just use a different tRNA for priming. 
C)  No, this would likely kill the cells that were drug treated, because they couldn't appropriately incorporate lysine into their proteins. 
D)  No, the priming function of the tRNA is not essential for the HIV life cycle. 
A)  Yes, it should stop the reverse transcription of the HIV genome with few side effects. 
B)  No, the virus would just use a different tRNA for priming. 
C)  No, this would likely kill the cells that were drug treated, because they couldn't appropriately incorporate lysine into their proteins. 
D)  No, the priming function of the tRNA is not essential for the HIV life cycle.

Question 3

The HIV genome is especially prone to mutation because

Accepted Answer

A)  it is made of DNA. 
B)  it is an emerging virus. 
C)  it is copied by reverse transcriptase, which lacks a proofreading function. 
D)  of the many different drugs HIV patients must take. 
A)  it is made of DNA. 
B)  it is an emerging virus. 
C)  it is copied by reverse transcriptase, which lacks a proofreading function. 
D)  of the many different drugs HIV patients must take.

Question 4

Both Phage Lambda and HIV use tail fibers to bind to their receptor proteins

Accepted Answer

A) True 
 B)False

Question 5

Latency in HIV occurs when

Accepted Answer

A)  the virus switches back to an active form. 
B)  new viral particles are made. 
C)  the viral genome forms an episome and remains dormant. 
D)  the virus integrates into the host genome and remains dormant. 
A)  the virus switches back to an active form. 
B)  new viral particles are made. 
C)  the viral genome forms an episome and remains dormant. 
D)  the virus integrates into the host genome and remains dormant.

Question 6

Reverse transcriptase copies

Accepted Answer

A)  DNA to DNA. 
B)  DNA to RNA. 
C)  RNA to DNA. 
D)  RNA to RNA. 
A)  DNA to DNA. 
B)  DNA to RNA. 
C)  RNA to DNA. 
D)  RNA to RNA.

Question 7

Infectious mononucleosis is caused by the Epstein-Barr virus, and patients often exhibit a fever, sore throat, swollen glands, and fatigue for several weeks. In some patients, the virus can reactivate later and cause physical symptoms once again. This is likely because

Accepted Answer

A)  they were misdiagnosed the first time, and only really were infected by the virus the second time they became sick. 
B)  the virus was latent in these patients, and then switched to the active form and began making new virus particles. 
C)  the patients had the virus initially, and they became sick again at the time the virus became latent. 
D)  the Epstein-Barr virus is an emerging virus so we do not know much about its infectious life cycle. 
A)  they were misdiagnosed the first time, and only really were infected by the virus the second time they became sick. 
B)  the virus was latent in these patients, and then switched to the active form and began making new virus particles. 
C)  the patients had the virus initially, and they became sick again at the time the virus became latent. 
D)  the Epstein-Barr virus is an emerging virus so we do not know much about its infectious life cycle.

Question 8

The HIV genome contains nine genes, and therefore encodes just nine proteins.

Accepted Answer

A) True 
 B)False

Question 9

Because tobacco mosaic virus has an RNA genome, it must encode a reverse transcriptase.

Accepted Answer

A) True 
 B)False

Question 10

In phage λ, the relative affinities of the lambda repressor and the cro protein to the three binding sites in the OR region are:

Accepted Answer

A)  the same. 
B)  inversely proportional. 
C)  unrelated. 
A)  the same. 
B)  inversely proportional. 
C)  unrelated.

Select the phage λ proteins that function as antiterminators (check all that apply).

The reverse transcription of HIV RNA utilizes host cell tRNA as a primer. Specifically, a tRNA for lysine is utilized. Would a drug that blocked the host cell synthesis of the tRNA for lysine be a good drug to prevent the HIV life cycle?

The HIV genome is especially prone to mutation because

Both Phage Lambda and HIV use tail fibers to bind to their receptor proteins

Latency in HIV occurs when

Reverse transcriptase copies

Infectious mononucleosis is caused by the Epstein-Barr virus, and patients often exhibit a fever, sore throat, swollen glands, and fatigue for several weeks. In some patients, the virus can reactivate later and cause physical symptoms once again. This is likely because

The HIV genome contains nine genes, and therefore encodes just nine proteins.

Because tobacco mosaic virus has an RNA genome, it must encode a reverse transcriptase.

In phage λ, the relative affinities of the lambda repressor and the cro protein to the three binding sites in the OR region are:

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional and Translation Regulation

Gene Regulation in Eukaryotes Ii: Epigenetics

Non-Coding Rnas

Gene Mutation and Dna Repair

Recombination, Immunogenetics, and Transposition

Molecular Technologies

Biotechnology

Genomics I: Analysis of Dna

Genomics Ii: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Complex and Quantitative Traits

Evolutionary Genetics

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Exam 18: Genetics of Viruses

Select the phage λ proteins that function as antiterminators (check all that apply).

The reverse transcription of HIV RNA utilizes host cell tRNA as a primer. Specifically, a tRNA for lysine is utilized. Would a drug that blocked the host cell synthesis of the tRNA for lysine be a good drug to prevent the HIV life cycle?

The HIV genome is especially prone to mutation because

Both Phage Lambda and HIV use tail fibers to bind to their receptor proteins

Latency in HIV occurs when

Reverse transcriptase copies

Infectious mononucleosis is caused by the Epstein-Barr virus, and patients often exhibit a fever, sore throat, swollen glands, and fatigue for several weeks. In some patients, the virus can reactivate later and cause physical symptoms once again. This is likely because

The HIV genome contains nine genes, and therefore encodes just nine proteins.

Because tobacco mosaic virus has an RNA genome, it must encode a reverse transcriptase.

In phage λ, the relative affinities of the lambda repressor and the cro protein to the three binding sites in the OR region are:

Overview of Genetics

Mendelian Inheritance

Chromosome Transmission During Cell Division and Sexual Reproduction

Extensions of Mendelian Inheritance

Non-Mendelian Inheritance

Genetic Linkage and Mapping in Eukaryotes

Genetic Transfer and Mapping in Bacteria

Variation in Chromosome Structure and Number

Molecular Structure of Dna and Rna

Chromosome Organization and Molecular Structure

Dna Replication

Gene Transcription and Rna Modification

Translation of Mrna

Gene Regulation in Bacteria

Gene Regulation in Eukaryotes I: Transcriptional and Translation Regulation

Gene Regulation in Eukaryotes Ii: Epigenetics

Non-Coding Rnas

Gene Mutation and Dna Repair

Recombination, Immunogenetics, and Transposition

Molecular Technologies

Biotechnology

Genomics I: Analysis of Dna

Genomics Ii: Functional Genomics, Proteomics, and Bioinformatics

Medical Genetics and Cancer

Developmental Genetics

Population Genetics

Complex and Quantitative Traits

Evolutionary Genetics

Filters