Exam 15: Regulation of Gene Expression

Genomic imprinting, DNA methylation, and histone acetylation are all examples of

Allolactose, an isomer of lactose, is formed in small amounts from lactose. An E. coli cell is presented for the first time with the sugar lactose (containing allolactose) as a potential food source. Which of the following occurs when the lactose enters the cell?

A mutation that inactivates the regulatory gene of a repressible operon in an E. coli cell would result in

Steroid hormones produce their effects in cells by

There is a mutation in the repressor that results in a molecule known as a super-repressor because it represses the lac operon permanently. Which of these would characterize such a mutant?

In response to chemical signals, prokaryotes can do which of the following?

Which one of the following techniques involves reverse transcriptase, PCR amplification, and gel electrophoresis?

Which of the following mechanisms is used to coordinate the expression of multiple, related genes in eukaryotic cells?

Which of the following statements about the DNA in one of your brain cells is true?

Which of the following is most likely to have a small protein called ubiquitin attached to it?

In positive control of several sugar-metabolism-related operons, the catabolite activator protein (CAP) binds to DNA to stimulate transcription. What causes an increase in CAP?

You are given an experimental problem involving control of a gene's expression in the embryo of a particular species. One of your first questions is whether the gene's expression is controlled at the level of transcription or translation. Which of the following might best give you an answer?

Among the newly discovered small noncoding RNAs, one type reestablishes methylation patterns during gamete formation and blocks expression of some transposons. These are known as

15.2 Art Question Figure 15.1 -In the microarray shown in Figure 15.1, if you were searching for genes whose expression was inhibited by hormone treatment, you would search for sequences spotted on the array that showed ________ fluorescence.

The role of a metabolite that controls a repressible operon is to

The functioning of enhancers is an example of

For a repressible operon to be transcribed, which of the following must occur?

Suppose an experimenter becomes proficient with a technique that allows her to move DNA sequences within a prokaryotic genome. -If she moves the operator to the far end of the operon, past the transacetylase (lacA) gene, which of the following would likely occur when the cell is exposed to lactose?

Transcription factors in eukaryotes usually have DNA binding domains as well as other domains that are also specific for binding. In general, which of the following would you expect many of them to be able to bind?

Which of the following is an example of post-transcriptional control of gene expression?