Question 1

With respect to cancer genetics and the cancer genome,what are passenger genes?

Accepted Answer

A) genes that are subject to mutation but have no effect on the phenotype of a cancer cell 
B) genes that are not subject to mutation and have no effect on the phenotype of a cancer cell 
C) genes that are subject to mutation but have a large effect on the phenotype of a cancer cell 
D) genes that are subject to mutation but have no effect on the genotype of a cancer cell 
E) genes that are subject to mutation but have no effect on the phenotype of an egg cell 
A) genes that are subject to mutation but have no effect on the phenotype of a cancer cell 
B) genes that are not subject to mutation and have no effect on the phenotype of a cancer cell 
C) genes that are subject to mutation but have a large effect on the phenotype of a cancer cell 
D) genes that are subject to mutation but have no effect on the genotype of a cancer cell 
E) genes that are subject to mutation but have no effect on the phenotype of an egg cell

Question 2

What is a xenograft?

Accepted Answer

A) transplanting cells in the presence of xenon 
B) transplant of cells from one organism to an organism of a different species 
C) mixing cells from two different species in a culture dish 
D) a transplant that does not have a good histocompatibility antigen match 
E) a skin graft from one organism to another within the same species 
A) transplanting cells in the presence of xenon 
B) transplant of cells from one organism to an organism of a different species 
C) mixing cells from two different species in a culture dish 
D) a transplant that does not have a good histocompatibility antigen match 
E) a skin graft from one organism to another within the same species

Question 3

PKA,phosphoinositide PIP2

Accepted Answer

A) 1 
B) 2 
C) 3 
D) 4 
E) 1 and 3 
A) 1 
B) 2 
C) 3 
D) 4 
E) 1 and 3

Question 4

What is the material called serum that is added to culture media?

Accepted Answer

A) any sugary solution 
B) the fluid fraction of the blood 
C) the particulate fraction of the blood 
D) the combination of the fluid and particulate fractions of the blood 
E) any blood that has been in a syringe 
A) any sugary solution 
B) the fluid fraction of the blood 
C) the particulate fraction of the blood 
D) the combination of the fluid and particulate fractions of the blood 
E) any blood that has been in a syringe

Question 5

Which type of new screening test will be able to identify cancers based on the relative levels of various proteins in the blood?

Accepted Answer

A) genomics 
B) Pap smear 
C) colonoscopy 
D) proteomics 
E) astronomics 
A) genomics 
B) Pap smear 
C) colonoscopy 
D) proteomics 
E) astronomics

Question 6

Raf is a ________ protein kinase that resides at the head of the _______.

Accepted Answer

A) tyrosine,MAP kinase cascade 
B) serine/threonine,MAP kinase cascade 
C) tyrosine,glucagon cascade 
D) serine/threonine.glucagon cascade 
E) serine/threonine,apoptosis cascade 
A) tyrosine,MAP kinase cascade 
B) serine/threonine,MAP kinase cascade 
C) tyrosine,glucagon cascade 
D) serine/threonine.glucagon cascade 
E) serine/threonine,apoptosis cascade

Question 7

A single layer of cells that covers a culture dish is called a(n)_________.

Accepted Answer

A) duolayer 
B) imperium 
C) monolayer 
D) unolayer 
E) Unitarian 
A) duolayer 
B) imperium 
C) monolayer 
D) unolayer 
E) Unitarian

Question 8

What evidence suggested that the elevated sensitivity of cancer cells to radiation therapy and chemotherapy was not due to their more rapid division?

Accepted Answer

A) Cells that divide more quickly reproduce more effectively. 
B) Some cancer cells divide more slowly than their normal counterparts,yet they are still more sensitive to drugs and radiation than are normal cells. 
C) Cells that divide more quickly reproduce less effectively. 
D) Some cancer cells divide more quickly than their normal counterparts,yet they are still more sensitive to drugs and radiation than are normal cells. 
E) Normal cells dividing more slowly than tumor cells are more sensitive to drugs and radiation. 
A) Cells that divide more quickly reproduce more effectively. 
B) Some cancer cells divide more slowly than their normal counterparts,yet they are still more sensitive to drugs and radiation than are normal cells. 
C) Cells that divide more quickly reproduce less effectively. 
D) Some cancer cells divide more quickly than their normal counterparts,yet they are still more sensitive to drugs and radiation than are normal cells. 
E) Normal cells dividing more slowly than tumor cells are more sensitive to drugs and radiation.

Question 9

What happens quite often to the number of normal receptors in the plasma membranes of malignant cells as compared to normal cells?

Accepted Answer

A) Malignant cells usually have the same number of receptors in their plasma membranes as normal cells. 
B) Malignant cells usually have a much larger number of plasma membrane receptors than normal cells. 
C) Malignant cells usually have a much smaller number of plasma membrane receptors than normal cells. 
D) Malignant cells usually have no plasma membrane receptors,while normal cells have them. 
E) None of these are correct. 
A) Malignant cells usually have the same number of receptors in their plasma membranes as normal cells. 
B) Malignant cells usually have a much larger number of plasma membrane receptors than normal cells. 
C) Malignant cells usually have a much smaller number of plasma membrane receptors than normal cells. 
D) Malignant cells usually have no plasma membrane receptors,while normal cells have them. 
E) None of these are correct.

Question 10

When telomerase appears in a cell,it is not because the coding sequences of the gene have been changed.Instead,the protein produced is essentially normal,but it is being produced at an abnormal time.A gene that is normally repressed has been activated for some reason.Such an alteration in cell behavior is referred to as a(n)_________ change.

Accepted Answer

A) androgenous 
B) mutational 
C) epigenetic 
D) structural 
E) ancillary 
A) androgenous 
B) mutational 
C) epigenetic 
D) structural 
E) ancillary

Question 11

What is the most important property of a cancer cell,whether it is in the body or the culture dish?

Accepted Answer

A) its chromosome complement 
B) its loss of growth control 
C) its size 
D) its secretions 
E) its inability to divide 
A) its chromosome complement 
B) its loss of growth control 
C) its size 
D) its secretions 
E) its inability to divide

Question 12

__________ is new blood vessel formation.

Accepted Answer

A) Vesselogeny 
B) Angiogenesis 
C) Formational vessels 
D) Angiotension 
E) Venogenesis 
A) Vesselogeny 
B) Angiogenesis 
C) Formational vessels 
D) Angiotension 
E) Venogenesis

Question 13

Retinoblastoma is inherited as a ____________.

Accepted Answer

A) dominant genetic trait 
B) recessive genetic trait 
C) sex-linked recessive treat 
D) sex-linked dominant trait 
E) codominant trait 
A) dominant genetic trait 
B) recessive genetic trait 
C) sex-linked recessive treat 
D) sex-linked dominant trait 
E) codominant trait

Question 14

________ is a humanized antibody directed against a cell surface receptor called _____ that binds a growth factor responsible for stimulating the proliferation of breast cancer cells.

Accepted Answer

A) Ascriptin,Asc3 
B) Herceptin,Her2 
C) Apcolin,Apc2 
D) Herceptin.Raf 
E) Rafinolin,Raf 
A) Ascriptin,Asc3 
B) Herceptin,Her2 
C) Apcolin,Apc2 
D) Herceptin.Raf 
E) Rafinolin,Raf

With respect to cancer genetics and the cancer genome,what are passenger genes?

What is a xenograft?

PKA,phosphoinositide PIP2

What is the material called serum that is added to culture media?

Which type of new screening test will be able to identify cancers based on the relative levels of various proteins in the blood?

Raf is a __ protein kinase that resides at the head of the _.

A single layer of cells that covers a culture dish is called a(n)_________.

What evidence suggested that the elevated sensitivity of cancer cells to radiation therapy and chemotherapy was not due to their more rapid division?

What happens quite often to the number of normal receptors in the plasma membranes of malignant cells as compared to normal cells?

What is the most important property of a cancer cell,whether it is in the body or the culture dish?

__________ is new blood vessel formation.

Retinoblastoma is inherited as a ____________.

____ is a humanized antibody directed against a cell surface receptor called _ that binds a growth factor responsible for stimulating the proliferation of breast cancer cells.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Exam 16: Cancer

With respect to cancer genetics and the cancer genome,what are passenger genes?

What is a xenograft?

PKA,phosphoinositide PIP2

What is the material called serum that is added to culture media?

Which type of new screening test will be able to identify cancers based on the relative levels of various proteins in the blood?

Raf is a ________ protein kinase that resides at the head of the _______.

A single layer of cells that covers a culture dish is called a(n)_________.

What evidence suggested that the elevated sensitivity of cancer cells to radiation therapy and chemotherapy was not due to their more rapid division?

What happens quite often to the number of normal receptors in the plasma membranes of malignant cells as compared to normal cells?

What is the most important property of a cancer cell,whether it is in the body or the culture dish?

__________ is new blood vessel formation.

Retinoblastoma is inherited as a ____________.

________ is a humanized antibody directed against a cell surface receptor called _____ that binds a growth factor responsible for stimulating the proliferation of breast cancer cells.

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

The Immune Response

Techniques in Cell and Molecular Biology

Filters

Raf is a __ protein kinase that resides at the head of the _.

____ is a humanized antibody directed against a cell surface receptor called _ that binds a growth factor responsible for stimulating the proliferation of breast cancer cells.