Question 1

Cytokines utilize a novel signal transduction pathway referred to as the ____ pathway,which operates without the involvement of _____.

Accepted Answer

A) cytokine-specific,receptors 
B) JAK-STAT,second messengers 
C) cytokine-mediated,transducers 
D) JAX-TAT,tyrosine kinases 
E) Jack Sprat,fats 
A) cytokine-specific,receptors 
B) JAK-STAT,second messengers 
C) cytokine-mediated,transducers 
D) JAX-TAT,tyrosine kinases 
E) Jack Sprat,fats

Question 2

Some of the activated B cells remain in lymphoid tissue and respond rapidly at a later date if the antigen reappears in the body.Such cells are called __________.

Accepted Answer

A) memory B cells 
B) activation B cells 
C) plasma cells 
D) secretion cells 
E) antibody-producing cells 
A) memory B cells 
B) activation B cells 
C) plasma cells 
D) secretion cells 
E) antibody-producing cells

Question 3

What fatal disease is characterized by severe autoimmunity in newborn infants and is caused by a mutation in a gene that encodes a transcription factor required for the differentiation of Treg cells?

Accepted Answer

A) IPEX 
B) IBEX 
C) multiple sclerosis 
D) sudden infant death syndrome 
E) Tay-Sachs disease 
A) IPEX 
B) IBEX 
C) multiple sclerosis 
D) sudden infant death syndrome 
E) Tay-Sachs disease

Question 4

Which cells are responsible for mediating cell-mediated immunity?

Accepted Answer

A) T cells or T lymphocytes 
B) antigen cells 
C) B cells or B lymphocytes 
D) platelets 
E) erythrocytes 
A) T cells or T lymphocytes 
B) antigen cells 
C) B cells or B lymphocytes 
D) platelets 
E) erythrocytes

Question 5

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

Accepted Answer

A) protein rearrangements in the genome 
B) RNA rearrangements in the genome 
C) DNA rearrangements in the genome 
D) DNA rearrangements in the mitochondria 
E) spontaneous production of proteins in the Golgi complex 
A) protein rearrangements in the genome 
B) RNA rearrangements in the genome 
C) DNA rearrangements in the genome 
D) DNA rearrangements in the mitochondria 
E) spontaneous production of proteins in the Golgi complex

Question 6

_________ screen body cells for aged,infected and,in some cases,malignant cells and,if such cells are detected,they are attacked and killed.

Accepted Answer

A) Helper T lymphocytes 
B) Inhibitory T lymphocytes 
C) Cytotoxic T lymphocytes 
D) Regulatory T lymphocytes 
E) B lymphocytes 
A) Helper T lymphocytes 
B) Inhibitory T lymphocytes 
C) Cytotoxic T lymphocytes 
D) Regulatory T lymphocytes 
E) B lymphocytes

Question 7

Which of the following is characteristic of immature T cells that have just migrated to the thymus gland from the bone marrow?

Accepted Answer

A) They lack lobed nuclei. 
B) They lack cell surface proteins that mediate T-cell function,most notably TCRs. 
C) They possess a diverse population of plasma membrane proteins. 
D) They have a low amount of rough ER. 
E) They have a large number of pseudopodia. 
A) They lack lobed nuclei. 
B) They lack cell surface proteins that mediate T-cell function,most notably TCRs. 
C) They possess a diverse population of plasma membrane proteins. 
D) They have a low amount of rough ER. 
E) They have a large number of pseudopodia.

Question 8

Cells of the innate immune system have receptors on their surfaces that help them to recognize ____________.

Accepted Answer

A) the DNA of invading pathogens 
B) the RNA of invading pathogens 
C) conserved macromolecules that are characteristic of viruses and bacteria 
D) conserved chemical groupings that are characteristic of other white blood cells 
E) the cell surfaces of viruses 
A) the DNA of invading pathogens 
B) the RNA of invading pathogens 
C) conserved macromolecules that are characteristic of viruses and bacteria 
D) conserved chemical groupings that are characteristic of other white blood cells 
E) the cell surfaces of viruses

Question 9

Introduction of antibodies made against a particular invading organism into another organism by injection or some other similar method is called ____________.

Accepted Answer

A) active immunity 
B) primary immunity 
C) secondary immunity 
D) passive immunity 
E) tertiary immunity 
A) active immunity 
B) primary immunity 
C) secondary immunity 
D) passive immunity 
E) tertiary immunity

Question 10

Which cells of the immune system produce IFN-$\gamma$ and protect the body against intracellular pathogens by activating macrophages to kill pathogens they might harbor?

Accepted Answer

A) TH1 cells 
B) TH2 cells 
C) cytotoxic T lymphocytes 
D) B cells 
E) regulatory T lymphocytes 
A) TH1 cells 
B) TH2 cells 
C) cytotoxic T lymphocytes 
D) B cells 
E) regulatory T lymphocytes

Question 11

What subfamily of small cytokines acts primarily as chemoattractants that stimulate the migration of lymphocytes into inflamed tissue?

Accepted Answer

A) minicytokines 
B) interleukins 
C) chemokines 
D) interferons 
E) tumor necrosis factors 
A) minicytokines 
B) interleukins 
C) chemokines 
D) interferons 
E) tumor necrosis factors

Question 12

What is the source of B cells?

Accepted Answer

A) T cells 
B) a population of undifferentiated and indistinguishable progenitor cells 
C) a population of differentiated and specific progenitor cells 
D) a population of undifferentiated and indistinguishable descendent cells 
E) platelets 
A) T cells 
B) a population of undifferentiated and indistinguishable progenitor cells 
C) a population of differentiated and specific progenitor cells 
D) a population of undifferentiated and indistinguishable descendent cells 
E) platelets

Question 13

Which type of immunity is carried out by antibodies and mediated by B lymphocytes?

Accepted Answer

A) humorous immunity 
B) cell-mediated immunity 
C) lymphocytic immunity 
D) humoral immunity 
E) surface-mediated immunity 
A) humorous immunity 
B) cell-mediated immunity 
C) lymphocytic immunity 
D) humoral immunity 
E) surface-mediated immunity

Question 14

Which antibodies are the predominant antibodies found in blood and lymph during a secondary response to most antigens?

Accepted Answer

A) IgGs 
B) IgAs 
C) IgMs 
D) IgEs 
E) IgDs 
A) IgGs 
B) IgAs 
C) IgMs 
D) IgEs 
E) IgDs

Question 15

A helper T cell that secretes ______ induces a switch in the adjacent B cell from IgM synthesis to one of the IgG classes.

Accepted Answer

A) IFN-$\alpha$ 
B) IFN-$\gamma$ 
C) IFN-$\beta$ 
D) interleukin-1 
E) glucagons 
A) IFN-$\alpha$ 
B) IFN-$\gamma$ 
C) IFN-$\beta$ 
D) interleukin-1 
E) glucagons

Question 16

Genes encoding antibodies are generated by a process in which DNA segments are _______ combined.

Accepted Answer

A) randomly 
B) purposely 
C) slowly 
D) rapidly 
E) incompletely 
A) randomly 
B) purposely 
C) slowly 
D) rapidly 
E) incompletely

Question 17

Antigens that originate within the cytosol of a cell are referred to as __________.

Accepted Answer

A) endogenous proteins 
B) exogenous proteins 
C) cytosolic proteins 
D) phagocytic proteins 
E) enterogenous proteins 
A) endogenous proteins 
B) exogenous proteins 
C) cytosolic proteins 
D) phagocytic proteins 
E) enterogenous proteins

Question 18

What process is probably responsible for the origin of the three parts of the constant portion of the IgG heavy chain?

Accepted Answer

A) inversion of an ancestral gene coding for an Ig unit about 110 amino acids long 
B) duplication of an ancestral gene coding for an Ig unit about 110 amino acids long 
C) deletion of an ancestral gene coding for an Ig unit about 110 amino acids long 
D) point mutation of an ancestral gene coding for an Ig unit about 110 amino acids long 
E) nonsense mutation of an ancestral gene coding for an Ig unit about 110 amino acids long 
A) inversion of an ancestral gene coding for an Ig unit about 110 amino acids long 
B) duplication of an ancestral gene coding for an Ig unit about 110 amino acids long 
C) deletion of an ancestral gene coding for an Ig unit about 110 amino acids long 
D) point mutation of an ancestral gene coding for an Ig unit about 110 amino acids long 
E) nonsense mutation of an ancestral gene coding for an Ig unit about 110 amino acids long

Question 19

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

Accepted Answer

A) antigens 
B) albumins 
C) heparins 
D) antibodies 
E) thrombospondins 
A) antigens 
B) albumins 
C) heparins 
D) antibodies 
E) thrombospondins

Question 20

What is the name of the type of cell that serves as the direct precursor cell for both B cells and T cells?

Accepted Answer

A) hematopelagic stem cells 
B) the fertilized egg 
C) the hematopoietic stem cell 
D) the pluripotent hepatologic stem cell 
E) the sperm cell 
A) hematopelagic stem cells 
B) the fertilized egg 
C) the hematopoietic stem cell 
D) the pluripotent hepatologic stem cell 
E) the sperm cell

Cytokines utilize a novel signal transduction pathway referred to as the pathway,which operates without the involvement of _.

Some of the activated B cells remain in lymphoid tissue and respond rapidly at a later date if the antigen reappears in the body.Such cells are called __________.

What fatal disease is characterized by severe autoimmunity in newborn infants and is caused by a mutation in a gene that encodes a transcription factor required for the differentiation of Treg cells?

Which cells are responsible for mediating cell-mediated immunity?

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

_________ screen body cells for aged,infected and,in some cases,malignant cells and,if such cells are detected,they are attacked and killed.

Which of the following is characteristic of immature T cells that have just migrated to the thymus gland from the bone marrow?

Cells of the innate immune system have receptors on their surfaces that help them to recognize ____________.

Introduction of antibodies made against a particular invading organism into another organism by injection or some other similar method is called ____________.

Which cells of the immune system produce IFN- $\gamma$ and protect the body against intracellular pathogens by activating macrophages to kill pathogens they might harbor?

What subfamily of small cytokines acts primarily as chemoattractants that stimulate the migration of lymphocytes into inflamed tissue?

What is the source of B cells?

Which type of immunity is carried out by antibodies and mediated by B lymphocytes?

Which antibodies are the predominant antibodies found in blood and lymph during a secondary response to most antigens?

A helper T cell that secretes ______ induces a switch in the adjacent B cell from IgM synthesis to one of the IgG classes.

Genes encoding antibodies are generated by a process in which DNA segments are _______ combined.

Antigens that originate within the cytosol of a cell are referred to as __________.

What process is probably responsible for the origin of the three parts of the constant portion of the IgG heavy chain?

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

What is the name of the type of cell that serves as the direct precursor cell for both B cells and T cells?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

Techniques in Cell and Molecular Biology

Filters

Exam 17: The Immune Response

Cytokines utilize a novel signal transduction pathway referred to as the ____ pathway,which operates without the involvement of _____.

Some of the activated B cells remain in lymphoid tissue and respond rapidly at a later date if the antigen reappears in the body.Such cells are called __________.

What fatal disease is characterized by severe autoimmunity in newborn infants and is caused by a mutation in a gene that encodes a transcription factor required for the differentiation of Treg cells?

Which cells are responsible for mediating cell-mediated immunity?

What causes a differentiating B cell to become committed to producing only one species of antibody molecule?

_________ screen body cells for aged,infected and,in some cases,malignant cells and,if such cells are detected,they are attacked and killed.

Which of the following is characteristic of immature T cells that have just migrated to the thymus gland from the bone marrow?

Cells of the innate immune system have receptors on their surfaces that help them to recognize ____________.

Introduction of antibodies made against a particular invading organism into another organism by injection or some other similar method is called ____________.

Which cells of the immune system produce IFN- γ\gammaγ and protect the body against intracellular pathogens by activating macrophages to kill pathogens they might harbor?

What subfamily of small cytokines acts primarily as chemoattractants that stimulate the migration of lymphocytes into inflamed tissue?

What is the source of B cells?

Which type of immunity is carried out by antibodies and mediated by B lymphocytes?

Which antibodies are the predominant antibodies found in blood and lymph during a secondary response to most antigens?

A helper T cell that secretes ______ induces a switch in the adjacent B cell from IgM synthesis to one of the IgG classes.

Genes encoding antibodies are generated by a process in which DNA segments are _______ combined.

Antigens that originate within the cytosol of a cell are referred to as __________.

What process is probably responsible for the origin of the three parts of the constant portion of the IgG heavy chain?

Which of the following are globular,blood-borne proteins of the immunoglobulin superfamily (IgSF)?

What is the name of the type of cell that serves as the direct precursor cell for both B cells and T cells?

Introduction to the Study of Cell and Molecular Biology

The Chemical Basis of Life

Bioenergetics,enzymes and Metabolism

The Structure and Function of the Plasma Membrane

Aerobic Respiration and the Mitochondrion

Photosynthesis and the Chloroplast

Interactions Between Cells and Their Environment

Cytoplasmic Membrane Systems: Structure, function, and Membrane Trafficking

The Cytoskeleton and Cell Motility

The Nature of the Gene and the Genome

Gene Expression: From Transcription to Translation

Control of Gene Expression

Dna Replication and Repair

Cellular Reproduction

Cell Signaling and Signal Transduction: Communication Between Cells

Cancer

Techniques in Cell and Molecular Biology

Filters

Cytokines utilize a novel signal transduction pathway referred to as the pathway,which operates without the involvement of _.

Which cells of the immune system produce IFN- $\gamma$ and protect the body against intracellular pathogens by activating macrophages to kill pathogens they might harbor?