Question 1

T-independent antigens:

Accepted Answer

A)  stimulate primarily an IgM response 
B)  stimulate primarily an IgG response 
C)  cause an anamnestic response 
D)  induce production of memory 
A)  stimulate primarily an IgM response 
B)  stimulate primarily an IgG response 
C)  cause an anamnestic response 
D)  induce production of memory

Question 2

The ability to respond to antigen depends on which of the following factors?

Accepted Answer

A)  age 
B)  proper nutrition 
C)  genetic predisposition 
D)  all of the above 
E)  all except one of the above 
A)  age 
B)  proper nutrition 
C)  genetic predisposition 
D)  all of the above 
E)  all except one of the above

Question 3

A macromolecule that is capable of eliciting an immune response in an immunocompetent host is called a(an):

Accepted Answer

A)  antigen 
B)  antibody 
C)  hapten 
D)  acute phase reactant 
A)  antigen 
B)  antibody 
C)  hapten 
D)  acute phase reactant

Question 4

Blood from a suspect is typed to see if it is a match with a sample found at the crime scene.The suspect's blood exhibits the following reactions: no agglutination with anti-A,no agglutination with anti-B.What is the suspect's blood type?

Accepted Answer

A)  type A 
B)  type B 
C)  type O 
D)  type AB 
A)  type A 
B)  type B 
C)  type O 
D)  type AB

Question 5

Endogenous peptides binding to HLA-A,B,or C molecules on the surface of hepatocytes is critical for the response by:

Accepted Answer

A)  B lymphocytes 
B)  T helper cells 
C)  cytotoxic T cells 
D)  macrophages 
A)  B lymphocytes 
B)  T helper cells 
C)  cytotoxic T cells 
D)  macrophages

Question 6

Which MHC class of antigens is necessary for antigen recognition by CD4-positive T cells?

Accepted Answer

A)  class I 
B)  class II 
C)  class III 
D)  No MHC molecule is necessary for antigen recognition. 
A)  class I 
B)  class II 
C)  class III 
D)  No MHC molecule is necessary for antigen recognition.

Question 7

Major histocompatibility (MHC)molecules containing beta-2-microglobulin:

Accepted Answer

A)  contain alpha and beta transmembrane polypeptides 
B)  participate in the activation of CD4 T cells 
C)  are determined by HLA-A,HLA-B,and HLA-C genes 
D)  are determined by the HLA-DR genes 
A)  contain alpha and beta transmembrane polypeptides 
B)  participate in the activation of CD4 T cells 
C)  are determined by HLA-A,HLA-B,and HLA-C genes 
D)  are determined by the HLA-DR genes

Question 8

A 50 kDa protein from a bacterial cell that has numerous different epitopes would be called:

Accepted Answer

A)  hapten,but not antigen 
B)  hapten and antigen 
C)  antigen,but not immunogen 
D)  immunogen and antigen 
A)  hapten,but not antigen 
B)  hapten and antigen 
C)  antigen,but not immunogen 
D)  immunogen and antigen

Question 9

Which of the following is true of HLA (MHC)class I antigens?

Accepted Answer

A)  They are recognized by helper T cells. 
B)  They are found on all nucleated cells. 
C)  They combine with exogenous antigen. 
D)  They are coded for on chromosome 9. 
A)  They are recognized by helper T cells. 
B)  They are found on all nucleated cells. 
C)  They combine with exogenous antigen. 
D)  They are coded for on chromosome 9.

Question 10

Which of the following best describes HLA class II molecules?

Accepted Answer

A)  They interact with CD8+ T cells. 
B)  They have an alpha chain and beta-2 microglobulin. 
C)  They have alpha and beta chains of equal size. 
D)  They combine with antigen made inside the cell. 
A)  They interact with CD8+ T cells. 
B)  They have an alpha chain and beta-2 microglobulin. 
C)  They have alpha and beta chains of equal size. 
D)  They combine with antigen made inside the cell.

Question 11

All of the following are characteristics of a good antigen EXCEPT:

Accepted Answer

A)  large molecule 
B)  foreign to host 
C)  repeating polymer 
D)  protein in nature 
A)  large molecule 
B)  foreign to host 
C)  repeating polymer 
D)  protein in nature

Question 12

Another name for antigenic determinant is:

Accepted Answer

A)  immunogen 
B)  epitope 
C)  antibody 
D)  polysaccharide 
A)  immunogen 
B)  epitope 
C)  antibody 
D)  polysaccharide

Question 13

Heterophile antigens are characterized as:

Accepted Answer

A)  found in unrelated plants or animals but cross-reacting with the same antibody 
B)  one's own self-antigens 
C)  any antigens used for immunization 
D)  all of the above 
A)  found in unrelated plants or animals but cross-reacting with the same antibody 
B)  one's own self-antigens 
C)  any antigens used for immunization 
D)  all of the above

Question 14

What is the function of TAP proteins used in antigen processing?

Accepted Answer

A)  help digest large proteins 
B)  bind to MHC Class II in the endoplasmic reticulum 
C)  measure and transport digested proteins to MHC Class I 
D)  recognize and digest exogenous protein 
A)  help digest large proteins 
B)  bind to MHC Class II in the endoplasmic reticulum 
C)  measure and transport digested proteins to MHC Class I 
D)  recognize and digest exogenous protein

Question 15

When a human responds to a bacterial antigen,the bacterial antigen is classified as a(an):

Accepted Answer

A)  autoantigen 
B)  alloantigen 
C)  heteroantigen 
D)  holoantigen 
A)  autoantigen 
B)  alloantigen 
C)  heteroantigen 
D)  holoantigen

Question 16

A substance that is too small to stimulate antibody production by itself unless it is attached to a larger carrier molecule is called a(an):

Accepted Answer

A)  autoantigen 
B)  cross-reacting antigen 
C)  hapten 
D)  alloantigen 
A)  autoantigen 
B)  cross-reacting antigen 
C)  hapten 
D)  alloantigen

Question 17

MHC class II antigens are recognized by which of the following cells?

Accepted Answer

A)  CD4+ T cells 
B)  CD8+ T cells 
C)  B cells 
D)  macrophages 
A)  CD4+ T cells 
B)  CD8+ T cells 
C)  B cells 
D)  macrophages

Question 18

If a mother is HLA A3A14/ B5B15/ Cw3Cw4,and her child is A3A9/B5B27/Cw4Cw7,which of the following men is the most likely candidate for the father?

Accepted Answer

A)  A5A9/B5B27/Cw3Cw7 
B)  A9A11/B15B21/Cw1Cw4 
C)  A4A15/B2B27/Cw1Cw5 
D)  A5A9/B17B27/Cw3Cw5 
A)  A5A9/B5B27/Cw3Cw7 
B)  A9A11/B15B21/Cw1Cw4 
C)  A4A15/B2B27/Cw1Cw5 
D)  A5A9/B17B27/Cw3Cw5

T-independent antigens:

The ability to respond to antigen depends on which of the following factors?

A macromolecule that is capable of eliciting an immune response in an immunocompetent host is called a(an):

Blood from a suspect is typed to see if it is a match with a sample found at the crime scene.The suspect's blood exhibits the following reactions: no agglutination with anti-A,no agglutination with anti-B.What is the suspect's blood type?

Endogenous peptides binding to HLA-A,B,or C molecules on the surface of hepatocytes is critical for the response by:

Which MHC class of antigens is necessary for antigen recognition by CD4-positive T cells?

Major histocompatibility (MHC)molecules containing beta-2-microglobulin:

A 50 kDa protein from a bacterial cell that has numerous different epitopes would be called:

Which of the following is true of HLA (MHC)class I antigens?

Which of the following best describes HLA class II molecules?

All of the following are characteristics of a good antigen EXCEPT:

Another name for antigenic determinant is:

Heterophile antigens are characterized as:

What is the function of TAP proteins used in antigen processing?

When a human responds to a bacterial antigen,the bacterial antigen is classified as a(an):

A substance that is too small to stimulate antibody production by itself unless it is attached to a larger carrier molecule is called a(an):

MHC class II antigens are recognized by which of the following cells?

If a mother is HLA A3A14/ B5B15/ Cw3Cw4,and her child is A3A9/B5B27/Cw4Cw7,which of the following men is the most likely candidate for the father?

Introduction and Natural Immunity

Lymphoid System

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Agglutination

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

Filters

Exam 3: Nature of Antigens and Major Histocompatibility Complex

T-independent antigens:

The ability to respond to antigen depends on which of the following factors?

A macromolecule that is capable of eliciting an immune response in an immunocompetent host is called a(an):

Blood from a suspect is typed to see if it is a match with a sample found at the crime scene.The suspect's blood exhibits the following reactions: no agglutination with anti-A,no agglutination with anti-B.What is the suspect's blood type?

Endogenous peptides binding to HLA-A,B,or C molecules on the surface of hepatocytes is critical for the response by:

Which MHC class of antigens is necessary for antigen recognition by CD4-positive T cells?

Major histocompatibility (MHC)molecules containing beta-2-microglobulin:

A 50 kDa protein from a bacterial cell that has numerous different epitopes would be called:

Which of the following is true of HLA (MHC)class I antigens?

Which of the following best describes HLA class II molecules?

All of the following are characteristics of a good antigen EXCEPT:

Another name for antigenic determinant is:

Heterophile antigens are characterized as:

What is the function of TAP proteins used in antigen processing?

When a human responds to a bacterial antigen,the bacterial antigen is classified as a(an):

A substance that is too small to stimulate antibody production by itself unless it is attached to a larger carrier molecule is called a(an):

MHC class II antigens are recognized by which of the following cells?

If a mother is HLA A3A14/ B5B15/ Cw3Cw4,and her child is A3A9/B5B27/Cw4Cw7,which of the following men is the most likely candidate for the father?

Introduction and Natural Immunity

Lymphoid System

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Agglutination

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

Filters