Question 1

Which is a characteristic of circulating neutrophils (PMN)?

Accepted Answer

A)  lyse cells with perforin 
B)  recognize antigen with an antigen-specific receptor 
C)  have surface receptors for Fc of IgG 
D)  have surface receptors for C5a 
A)  lyse cells with perforin 
B)  recognize antigen with an antigen-specific receptor 
C)  have surface receptors for Fc of IgG 
D)  have surface receptors for C5a C

Question 2

Which of the following are components of innate (natural)immunity?

Accepted Answer

A)  immunoglobulin 
B)  T helper cells 
C)  macrophages 
D)  B cells 
A)  immunoglobulin 
B)  T helper cells 
C)  macrophages 
D)  B cells C

Question 3

A white blood cell that is 16 to 18 $\mu$m in diameter,has a horseshoe-shaped nucleus,and is capable of further differentiation in the tissues best describes:

Accepted Answer

A)  neutrophil 
B)  eosinophil 
C)  basophil 
D)  monocyte 
A)  neutrophil 
B)  eosinophil 
C)  basophil 
D)  monocyte D

Question 4

All of the following are characteristic of a lymph node EXCEPT:

Accepted Answer

A)  filters drainage from tissues 
B)  colonized with T and B cells 
C)  between 1 and 25 mm in size 
D)  considered a primary or central lymphoid organ 
A)  filters drainage from tissues 
B)  colonized with T and B cells 
C)  between 1 and 25 mm in size 
D)  considered a primary or central lymphoid organ

Question 5

The respiratory burst is:

Accepted Answer

A)  an increase in oxygen consumption 
B)  pseudopodia extending around a particle 
C)  the release of granules from a cell 
D)  the sudden exhale of a cell 
A)  an increase in oxygen consumption 
B)  pseudopodia extending around a particle 
C)  the release of granules from a cell 
D)  the sudden exhale of a cell

Question 6

The ability to resist infection through normally present body functions best characterizes:

Accepted Answer

A)  autoimmunity 
B)  natural immunity 
C)  acquired immunity 
D)  alloimmunity 
A)  autoimmunity 
B)  natural immunity 
C)  acquired immunity 
D)  alloimmunity

Question 7

Acute phase reactants have been determined to be elevated in a patient.What does this result on its own indicate about the patient?

Accepted Answer

A)  Inflammation of unknown cause is present. 
B)  Patient has a leukemia but not a lymphoma. 
C)  This is a normal result. 
D)  There is a parasitic infection and not a viral infection. 
A)  Inflammation of unknown cause is present. 
B)  Patient has a leukemia but not a lymphoma. 
C)  This is a normal result. 
D)  There is a parasitic infection and not a viral infection.

Question 8

A white blood cell described as between 12 to 22 $\mu$m with a large horseshoe-shaped nucleus that further differentiates in the tissue to become a macrophage best describes:

Accepted Answer

A)  neutrophil 
B)  lymphocyte 
C)  basophil 
D)  monocyte 
A)  neutrophil 
B)  lymphocyte 
C)  basophil 
D)  monocyte

Question 9

If a slide test for CRP is positive,what does this indicate?

Accepted Answer

A)  It is a nonspecific indicator of inflammation. 
B)  Patient has lupus. 
C)  Patient is immunocompromised. 
D)  Patient has a strep infection. 
A)  It is a nonspecific indicator of inflammation. 
B)  Patient has lupus. 
C)  Patient is immunocompromised. 
D)  Patient has a strep infection.

Question 10

Where does the immune response to foreign antigen in the tissue mainly occur?

Accepted Answer

A)  lymph nodes 
B)  blood 
C)  bone marrow 
D)  skin 
A)  lymph nodes 
B)  blood 
C)  bone marrow 
D)  skin

Question 11

Oxidative killing involves which of the following?

Accepted Answer

A)  perforin and granzymes 
B)  activation of complement 
C)  direct cytokine-mediated killing 
D)  formation of reactive oxygen intermediates 
A)  perforin and granzymes 
B)  activation of complement 
C)  direct cytokine-mediated killing 
D)  formation of reactive oxygen intermediates

Question 12

All of the following are considered part of natural immunity EXCEPT:

Accepted Answer

A)  eosinophils 
B)  lymphocytes 
C)  acute phase reactants 
D)  neutrophils 
A)  eosinophils 
B)  lymphocytes 
C)  acute phase reactants 
D)  neutrophils

Question 13

Which of the following is considered part of the internal defense system?

Accepted Answer

A)  cilia 
B)  mucous membranes 
C)  neutrophils 
D)  acidity of the skin 
A)  cilia 
B)  mucous membranes 
C)  neutrophils 
D)  acidity of the skin

Question 14

Neutrophils are characterized by all of the following EXCEPT:

Accepted Answer

A)  found in the marginating pool in blood vessels 
B)  capable of diapedesis 
C)  granules stain bright orange with Wright stain 
D)  segmented nucleus 
A)  found in the marginating pool in blood vessels 
B)  capable of diapedesis 
C)  granules stain bright orange with Wright stain 
D)  segmented nucleus

Question 15

A protein that only changes in concentration significantly in response to inflammation and is not detectable when there is no inflammation is called a/an:

Accepted Answer

A)  reagin 
B)  immunoglobulin 
C)  complement protein 
D)  acute phase protein 
A)  reagin 
B)  immunoglobulin 
C)  complement protein 
D)  acute phase protein

Question 16

All of the following are characteristic of acute phase reactants EXCEPT:

Accepted Answer

A)  increase rapidly in response to infection 
B)  used to diagnose a specific disease 
C)  enhance phagocytosis 
D)  promote inflammation 
A)  increase rapidly in response to infection 
B)  used to diagnose a specific disease 
C)  enhance phagocytosis 
D)  promote inflammation

Question 17

Which of the following are considered to be an acute phase protein?

Accepted Answer

A)  serum amyloid A 
B)  streptolysin O 
C)  cardiolipin 
D)  reagin 
A)  serum amyloid A 
B)  streptolysin O 
C)  cardiolipin 
D)  reagin

Question 18

Jenner's discovery that cowpox generated immunity against smallpox is based on the principle of:

Accepted Answer

A)  attenuation of a harmful substance 
B)  natural immunity 
C)  passive immunity 
D)  cross-immunity 
A)  attenuation of a harmful substance 
B)  natural immunity 
C)  passive immunity 
D)  cross-immunity

Question 19

Macrophages that migrate to the liver are called:

Accepted Answer

A)  alveolar macrophages 
B)  histiocytes 
C)  microglial cells 
D)  Kupffer cells 
A)  alveolar macrophages 
B)  histiocytes 
C)  microglial cells 
D)  Kupffer cells

Question 20

Which is characteristic of natural immunity?

Accepted Answer

A)  Memory is involved. 
B)  Lymphocytes play a major role. 
C)  It is very specific. 
D)  It depends on normally present body functions. 
A)  Memory is involved. 
B)  Lymphocytes play a major role. 
C)  It is very specific. 
D)  It depends on normally present body functions.

Exam 1: Introduction and Natural Immunity

Which is a characteristic of circulating neutrophils (PMN)?

Which of the following are components of innate (natural)immunity?

A white blood cell that is 16 to 18 μ\muμ m in diameter,has a horseshoe-shaped nucleus,and is capable of further differentiation in the tissues best describes:

All of the following are characteristic of a lymph node EXCEPT:

The respiratory burst is:

The ability to resist infection through normally present body functions best characterizes:

Acute phase reactants have been determined to be elevated in a patient.What does this result on its own indicate about the patient?

A white blood cell described as between 12 to 22 μ\muμ m with a large horseshoe-shaped nucleus that further differentiates in the tissue to become a macrophage best describes:

If a slide test for CRP is positive,what does this indicate?

Where does the immune response to foreign antigen in the tissue mainly occur?

Oxidative killing involves which of the following?

All of the following are considered part of natural immunity EXCEPT:

Which of the following is considered part of the internal defense system?

Neutrophils are characterized by all of the following EXCEPT:

A protein that only changes in concentration significantly in response to inflammation and is not detectable when there is no inflammation is called a/an:

All of the following are characteristic of acute phase reactants EXCEPT:

Which of the following are considered to be an acute phase protein?

Jenner's discovery that cowpox generated immunity against smallpox is based on the principle of:

Macrophages that migrate to the liver are called:

Which is characteristic of natural immunity?

Lymphoid System

Nature of Antigens and Major Histocompatibility Complex

Antibody Structure and Function

Cytokines

Complement System

Safety and Specimen Preparation

Precipitation Reactions

Agglutination

Labeled Immunoassays

Molecular Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Immunoproliferative Diseases

Immunodeficiency Disease

Transplantation Immunology

Tumor Immunology

Serologic and Molecular Detection of Bacterial Infections

Serologic and Molecular Detection of Bacterial Infections

Serology of Parasitic and Fungal Infections

Spirochete Diseases

Filters

A white blood cell that is 16 to 18 $\mu$ m in diameter,has a horseshoe-shaped nucleus,and is capable of further differentiation in the tissues best describes:

A white blood cell described as between 12 to 22 $\mu$ m with a large horseshoe-shaped nucleus that further differentiates in the tissue to become a macrophage best describes: