Exam 14: Autoimmunity

Lupus can be distinguished from rheumatoid arthritis on the basis of which of the following?

All of the following findings would be useful in the diagnosis of Graves' disease EXCEPT:

A 16-year-old male goes to his physician for an annual checkup.A routine urinalysis indicates the presence of blood,an increase in protein,and an increase in urea.The young man reports that he has been feeling tired and has a persistent cough.The doctor orders additional lab testing,including a serum test for rheumatoid factor,antinuclear antibody testing,anti-streptolysin O testing,and testing for the presence of anti-basement membrane antibodies.Only the latter test was positive.What is the most likely cause of the symptoms?

The characteristic ANA pattern produced by antibody to DNA-histone complex is:

In the RF test for rheumatoid arthritis,what is being detected?

A 40-year-old female patient has increased TSH and decreased rT3 and T4 levels with a normal T3 level.Antithyroglobulin is measured as 1:1280,and the antimicrosomal level is reportedly 1:6400.This patient most likely has:

A 30-year-old clinical laboratory sciences student complains of being tired,yet not able to sleep.The woman also states that her hair has been breaking off and she has lost 20 pounds over the last 2 months without trying.The woman's pulse and blood pressure are both elevated and her eyes seem to be bulging.Her CBC is normal,thyroid-stimulating hormone is decreased,and T4 is increased.Antimicrosomal and antithyroglobulin antibodies are each 1:400.This woman has:

Which of the following would be an indicator of systemic lupus?

A 45-year-old male presents to his physician complaining of achy joints,chronic runny nose,and coughing up blood.Chest x-ray shows pulmonary nodules.Cortisol is increased; ESR is slightly elevated.Tests for autoantibodies are positive for cytoplasmic antineutrophil cytoplasmic antibodies.This patient has: