Exam 6: Extension: B - The Influence of Drugs and Hormones on Behavior
Discuss some of the reasons why the same dose of a drug in the same person can have different effects at different times.
Learned tolerance and sensitization can alter the growth of dendrites and spine density as a function of the drug's effect and specific behaviors performed while exposed to the drug. This is believed to lead to increased or decreased responses to the drug based upon experience with it, independent of the dose of the drug.
Identify and describe the three kinds of drug tolerance.
In all cases these reactions to the drug follow repeated exposure to it: 1) metabolic tolerance, where the decreased response to a specific dosage of the drug is due to increased metabolism of the drug before it reaches its neural sites of action; 2) cellular tolerance, where the decreased response to a specific dosage of the drug is due to decreased cellular sensitivity to the drug; 3) leaned tolerance, where the decreased response to a specific dosage of the drug is due to learning to cope with life demands while under the influence of the drug.
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Match the item in each question with the most appropriate alternative in the list below.
-area postrema ___
A
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Match the item in each question with the correct alternative from the list below.
-metabolic tolerance ___
Compare the chemical messengers and target organs of the fast and slow pathways that contribute to the stress response.
Answer Key
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-MPTP ___
How do drugs such as Prozac affect serotonin levels at brain synapses?
Why must certain chemicals be transported to neurons within the brain? How is this accomplished?
What are the stages in the wanting - and - liking theory (incentive - sensitization theory) of drug addiction?
How do hormones such as insulin and cortisol act in opposition to maintain physiological function at an optimal level?
What are the mechanisms by which excessive glutamate release is thought to injure neurons?
Use the following to answer questions:
Match the drug in each question with the correct alternative from the list below.
-caffeine ___
Identify the barriers that an injected drug must cross to reach the brain.
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-nalorphine ___
What is the evidence that the dopamine system is involved in drug addiction?
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-Valium ___
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