Exam 6: Extension: B - The Influence of Drugs and Hormones on Behavior

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Discuss some of the reasons why the same dose of a drug in the same person can have different effects at different times.

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Learned tolerance and sensitization can alter the growth of dendrites and spine density as a function of the drug's effect and specific behaviors performed while exposed to the drug. This is believed to lead to increased or decreased responses to the drug based upon experience with it, independent of the dose of the drug.

Identify and describe the three kinds of drug tolerance.

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In all cases these reactions to the drug follow repeated exposure to it: 1) metabolic tolerance, where the decreased response to a specific dosage of the drug is due to increased metabolism of the drug before it reaches its neural sites of action; 2) cellular tolerance, where the decreased response to a specific dosage of the drug is due to decreased cellular sensitivity to the drug; 3) leaned tolerance, where the decreased response to a specific dosage of the drug is due to learning to cope with life demands while under the influence of the drug.

Use the following to answer questions: Match the item in each question with the most appropriate alternative in the list below. -area postrema ___

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Use the following to answer questions: Match the item in each question with the correct alternative from the list below. -metabolic tolerance ___

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What brain effects did Robinson see during amphetamine sensitization?

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Compare the chemical messengers and target organs of the fast and slow pathways that contribute to the stress response. Answer Key

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Use the following to answer questions: Match the item in each question with the most appropriate alternative in the list below. -MPTP ___

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What characterizes drugs that can easily reach the brain?

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Explain how activation of the GABA receptor can cause sedation.

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How do drugs such as Prozac affect serotonin levels at brain synapses?

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Why must certain chemicals be transported to neurons within the brain? How is this accomplished?

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What are the stages in the wanting - and - liking theory (incentive - sensitization theory) of drug addiction?

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How do hormones such as insulin and cortisol act in opposition to maintain physiological function at an optimal level?

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Compare and contrast the actions of neurotransmitters and hormones.

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What are the mechanisms by which excessive glutamate release is thought to injure neurons?

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Use the following to answer questions: Match the drug in each question with the correct alternative from the list below. -caffeine ___

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Identify the barriers that an injected drug must cross to reach the brain.

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Use the following to answer questions: Match the item in each question with the correct alternative from the list below. -nalorphine ___

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What is the evidence that the dopamine system is involved in drug addiction?

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Use the following to answer questions: Match the item in each question with the most appropriate alternative in the list below. -Valium ___

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