Question 1

Cold autoimmune hemolytic anemia is an example of which type of hypersensitivity?

Accepted Answer

A)  Type I 
B)  Type II 
C)  Type III 
D)  Type IV 
A)  Type I 
B)  Type II 
C)  Type III 
D)  Type IV

Question 2

All of the hypersensitivity responses have which of the following in common?

Accepted Answer

A)  Involvement of antibody 
B)  Asymptomatic sensitization phase 
C)  Release of histamine 
D)  Activation of macrophage against a pathogen. 
A)  Involvement of antibody 
B)  Asymptomatic sensitization phase 
C)  Release of histamine 
D)  Activation of macrophage against a pathogen.

Question 3

Which of the following diseases is an example of a type II hypersensitivity?

Accepted Answer

A)  Anaphylaxis 
B)  Myasthenia gravis 
C)  Post-streptococcal glomerulonephritis 
D)  Bruton's agammaglobulinemia 
A)  Anaphylaxis 
B)  Myasthenia gravis 
C)  Post-streptococcal glomerulonephritis 
D)  Bruton's agammaglobulinemia

Question 4

The principal difference between type II and type III hypersensitivity reactions is:

Accepted Answer

A)  the isotype of the antibody involved. 
B)  complement-mediated lysis of host cells. 
C)  whether the antigen is cellular or soluble. 
D)  involvement of helper T cells and macrophages. 
A)  the isotype of the antibody involved. 
B)  complement-mediated lysis of host cells. 
C)  whether the antigen is cellular or soluble. 
D)  involvement of helper T cells and macrophages.

Question 5

The normal activity of a type I hypersensitivity response is protection primarily against which of the following?

Accepted Answer

A)  Parasites 
B)  Viruses 
C)  Bacteria 
D)  Fungi 
A)  Parasites 
B)  Viruses 
C)  Bacteria 
D)  Fungi

Question 6

An exaggerated reaction directed against an antigen that is harmless is called:

Accepted Answer

A)  atopy. 
B)  hypersensitivity. 
C)  immune complex disease. 
D)  passive cutaneous anaphylaxis. 
A)  atopy. 
B)  hypersensitivity. 
C)  immune complex disease. 
D)  passive cutaneous anaphylaxis.

Question 7

A 5-year-old girl was rushed to the emergency department because she was having trouble breathing.She had been playing at the park when she fell down and her face and neck started to swell up.One of her friends thought that the girl might have been stung by a bee because a bee was flying around them,and shortly before the girl fell to the ground,she had screamed.The girl had a large red bump on her cheek.This girl likely has:

Accepted Answer

A)  Bruton's hypogammaglobulinemia. 
B)  type I diabetes. 
C)  type I hypersensitivity. 
D)  type IV hypersensitivity. 
A)  Bruton's hypogammaglobulinemia. 
B)  type I diabetes. 
C)  type I hypersensitivity. 
D)  type IV hypersensitivity.

Question 8

The precipitation of immune complexes in small blood vessels under the skin that occurs when antigen is injected in an animal with large amounts of circulating antibody describes which of the following?

Accepted Answer

A)  Serum sickness 
B)  Arthus reaction 
C)  Anaphylaxis 
D)  Delayed hypersensitivity 
A)  Serum sickness 
B)  Arthus reaction 
C)  Anaphylaxis 
D)  Delayed hypersensitivity

Question 9

Type I hypersensitivity involves:

Accepted Answer

A)  IgE binding to mast cells and basophils. 
B)  phagocytic cell degranulation and proteolytic enzyme activity. 
C)  a kidney membrane antigen and specific antibody. 
D)  natural killer cell activation. 
A)  IgE binding to mast cells and basophils. 
B)  phagocytic cell degranulation and proteolytic enzyme activity. 
C)  a kidney membrane antigen and specific antibody. 
D)  natural killer cell activation.

Question 10

Anaphylactic reactions are mediated by:

Accepted Answer

A)  mast cells. 
B)  lymphocytes. 
C)  macrophages. 
D)  natural killer cells. 
A)  mast cells. 
B)  lymphocytes. 
C)  macrophages. 
D)  natural killer cells.

Question 11

A 37-year-old woman received two units of packed red blood cells following a surgical procedure.She had been transfused once before.Five days after surgery,she experienced a slight fever and some hemoglobin in her urine,indicating a delayed transfusion reaction.A direct antiglobulin test on a blood sample was positive.Which of the following statements best describes this reaction?

Accepted Answer

A)  The patient had IgM antibody to the red cells transfused. 
B)  The patient's reaction was the result of an amnestic response. 
C)  Only IgE was coating the transfused red blood cells. 
D)  The antibody present reacted best at room temperature. 
A)  The patient had IgM antibody to the red cells transfused. 
B)  The patient's reaction was the result of an amnestic response. 
C)  Only IgE was coating the transfused red blood cells. 
D)  The antibody present reacted best at room temperature.

Question 12

Which isotype of immunoglobulin is involved in a type I hypersensitivity?

Accepted Answer

A)  IgE 
B)  IgA 
C)  IgG 
D)  IgM 
A)  IgE 
B)  IgA 
C)  IgG 
D)  IgM

Question 13

Which immune mechanism is involved in contact dermatitis?

Accepted Answer

A)  Presence of circulating IgE 
B)  Deposition of immune complexes 
C)  Activation of complement 
D)  Sensitization of cytotoxic T cells 
A)  Presence of circulating IgE 
B)  Deposition of immune complexes 
C)  Activation of complement 
D)  Sensitization of cytotoxic T cells

Question 14

Immune injury resulting from the localization of immune complexes in blood vessels and tissues describes which hypersensitivity reaction?

Accepted Answer

A)  I 
B)  II 
C)  III 
D)  IV 
A)  I 
B)  II 
C)  III 
D)  IV

Question 15

Which of the following is characteristic of autoimmune hemolytic anemia caused by cold agglutinins?

Accepted Answer

A)  It is a type I hypersensitivity reaction. 
B)  It is the most common cause of autoimmune hemolytic anemia. 
C)  The IgM antibodies are specific to Ii blood groups. 
D)  The reaction is irreversible. 
A)  It is a type I hypersensitivity reaction. 
B)  It is the most common cause of autoimmune hemolytic anemia. 
C)  The IgM antibodies are specific to Ii blood groups. 
D)  The reaction is irreversible.

Question 16

Complement is responsible for tissue damage in which of the following reactions?

Accepted Answer

A)  Immediate hypersensitivity 
B)  Type III hypersensitivity 
C)  Delayed hypersensitivity 
D)  Anaphylaxis 
A)  Immediate hypersensitivity 
B)  Type III hypersensitivity 
C)  Delayed hypersensitivity 
D)  Anaphylaxis

Cold autoimmune hemolytic anemia is an example of which type of hypersensitivity?

All of the hypersensitivity responses have which of the following in common?

Which of the following diseases is an example of a type II hypersensitivity?

The principal difference between type II and type III hypersensitivity reactions is:

The normal activity of a type I hypersensitivity response is protection primarily against which of the following?

An exaggerated reaction directed against an antigen that is harmless is called:

The precipitation of immune complexes in small blood vessels under the skin that occurs when antigen is injected in an animal with large amounts of circulating antibody describes which of the following?

Type I hypersensitivity involves:

Anaphylactic reactions are mediated by:

Which isotype of immunoglobulin is involved in a type I hypersensitivity?

Which immune mechanism is involved in contact dermatitis?

Immune injury resulting from the localization of immune complexes in blood vessels and tissues describes which hypersensitivity reaction?

Which of the following is characteristic of autoimmune hemolytic anemia caused by cold agglutinins?

Complement is responsible for tissue damage in which of the following reactions?

Introduction to Immunity and the Immune System

Nature of Antigens and the Major Histocompatibility Complex

Innate Immunity

Adaptive Immunity

Antibody Structure and Function

Cytokines

Complement System

Safety and Quality Management

Principles of Serological Testing

Precipitation and Agglutination Reactions

Labeled Immunoassays

Molecular Diagnostic Techniques

Flow Cytometry and Laboratory Automation

Autoimmunity

Transplantation Immunology

Tumor Immunology

Immunoproliferative Diseases

Immunodeficiency Diseases

Serological and Molecular Detection of Bacterial Infections

Spirochete Diseases

Serological and Molecular Diagnosis of Parasitic and Fungal Infections

Serology and Molecular Detection of Viral Infections

Laboratory Diagnosis of HIV Infection

Immunization and Vaccines

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Exam 14: Hypersensitivity

Cold autoimmune hemolytic anemia is an example of which type of hypersensitivity?

All of the hypersensitivity responses have which of the following in common?

Which of the following diseases is an example of a type II hypersensitivity?

The principal difference between type II and type III hypersensitivity reactions is:

The normal activity of a type I hypersensitivity response is protection primarily against which of the following?

An exaggerated reaction directed against an antigen that is harmless is called:

The precipitation of immune complexes in small blood vessels under the skin that occurs when antigen is injected in an animal with large amounts of circulating antibody describes which of the following?

Type I hypersensitivity involves:

Anaphylactic reactions are mediated by:

Which isotype of immunoglobulin is involved in a type I hypersensitivity?

Which immune mechanism is involved in contact dermatitis?

Immune injury resulting from the localization of immune complexes in blood vessels and tissues describes which hypersensitivity reaction?

Which of the following is characteristic of autoimmune hemolytic anemia caused by cold agglutinins?

Complement is responsible for tissue damage in which of the following reactions?

Introduction to Immunity and the Immune System

Nature of Antigens and the Major Histocompatibility Complex

Innate Immunity

Adaptive Immunity

Antibody Structure and Function

Cytokines

Complement System

Safety and Quality Management

Principles of Serological Testing

Precipitation and Agglutination Reactions

Labeled Immunoassays

Molecular Diagnostic Techniques

Flow Cytometry and Laboratory Automation

Autoimmunity

Transplantation Immunology

Tumor Immunology

Immunoproliferative Diseases

Immunodeficiency Diseases

Serological and Molecular Detection of Bacterial Infections

Spirochete Diseases

Serological and Molecular Diagnosis of Parasitic and Fungal Infections

Serology and Molecular Detection of Viral Infections

Laboratory Diagnosis of HIV Infection

Immunization and Vaccines

Filters