Question 1

Which of the following is NOT a characteristic of a lymph node?

Accepted Answer

A)  Filters interstitial fluid draining from tissues 
B)  Colonized with T and B cells 
C)  Between 1 and 25 mm in size 
D)  Considered a primary or central lymphoid organ 
A)  Filters interstitial fluid draining from tissues 
B)  Colonized with T and B cells 
C)  Between 1 and 25 mm in size 
D)  Considered a primary or central lymphoid organ

Question 2

All of the following are involved in adaptive immunity EXCEPT:

Accepted Answer

A)  memory. 
B)  lymphocytes. 
C)  specificity. 
D)  neutrophils. 
A)  memory. 
B)  lymphocytes. 
C)  specificity. 
D)  neutrophils.

Question 3

Which of the following are components of both innate and adaptive immune responses?

Accepted Answer

A)  Immunoglobulins 
B)  T helper cells 
C)  Macrophages 
D)  B cells. 
A)  Immunoglobulins 
B)  T helper cells 
C)  Macrophages 
D)  B cells.

Question 4

A primary site of antigen trapping and presentation to immune cells is the:

Accepted Answer

A)  spleen. 
B)  thymus. 
C)  bone marrow. 
D)  brain. 
A)  spleen. 
B)  thymus. 
C)  bone marrow. 
D)  brain.

Question 5

Macrophages that migrate to the liver are called:

Accepted Answer

A)  alveolar macrophages. 
B)  histiocytes. 
C)  microglial cells. 
D)  Kupffer cells. 
A)  alveolar macrophages. 
B)  histiocytes. 
C)  microglial cells. 
D)  Kupffer cells.

Question 6

Match each scientist with the appropriate immunological discovery.
-Humoral immunity

Accepted Answer

A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright 
A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright

Question 7

Which type of cell has a diameter between 10 and 15 micrometers,has a multi-lobed nucleus,and usually comprises more than 50% of circulating leukocytes?

Accepted Answer

A)  Neutrophil 
B)  Lymphocyte 
C)  Basophil 
D)  Monocyte 
A)  Neutrophil 
B)  Lymphocyte 
C)  Basophil 
D)  Monocyte

Question 8

Which of the following is a characteristic of opsonins?

Accepted Answer

A)  They are carbohydrates that stimulate T cells. 
B)  They are molecules that coat bacteria, making them more susceptible to phagocytosis. 
C)  They are expressed on the surface of neutrophils. 
D)  They are produced by NK cells. 
A)  They are carbohydrates that stimulate T cells. 
B)  They are molecules that coat bacteria, making them more susceptible to phagocytosis. 
C)  They are expressed on the surface of neutrophils. 
D)  They are produced by NK cells.

Question 9

Innate immunity can be characterized as:

Accepted Answer

A)  specific. 
B)  slow to respond. 
C)  dependent upon neutrophils and macrophages. 
D)  involving memory. 
A)  specific. 
B)  slow to respond. 
C)  dependent upon neutrophils and macrophages. 
D)  involving memory.

Question 10

Hematopoietic stem cells are located in the:

Accepted Answer

A)  lymph nodes. 
B)  spleen. 
C)  bone marrow. 
D)  thymus. 
A)  lymph nodes. 
B)  spleen. 
C)  bone marrow. 
D)  thymus.

Question 11

Where does the specific immune response to a foreign antigen mainly occur?

Accepted Answer

A)  Lymph nodes 
B)  Blood 
C)  Bone marrow 
D)  Skin 
A)  Lymph nodes 
B)  Blood 
C)  Bone marrow 
D)  Skin

Question 12

T cells mature in the:

Accepted Answer

A)  bone marrow. 
B)  thymus. 
C)  lymph nodes. 
D)  spleen. 
A)  bone marrow. 
B)  thymus. 
C)  lymph nodes. 
D)  spleen.

Question 13

Match each scientist with the appropriate immunological discovery.
-Vaccination

Accepted Answer

A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright 
A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright

Question 14

Which white cell in the peripheral blood migrates into tissue to become a macrophage?

Accepted Answer

A)  Eosinophil 
B)  Basophil 
C)  Neutrophil 
D)  Monocyte 
A)  Eosinophil 
B)  Basophil 
C)  Neutrophil 
D)  Monocyte

Question 15

Match each scientist with the appropriate immunological discovery.
-Opsonization

Accepted Answer

A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright 
A) Elie Metchnikoff 
B) Edward Jenner 
C) Emil Von Behring 
D) Almoth Wright

Question 16

A white blood cell that is 16 to 18 micrometers in diameter,has a horseshoe-shaped nucleus,and is capable of phagocytosis is a:

Accepted Answer

A)  neutrophil. 
B)  eosinophil. 
C)  basophil. 
D)  monocyte. 
A)  neutrophil. 
B)  eosinophil. 
C)  basophil. 
D)  monocyte.

Question 17

Which of the following is characteristic of natural immunity?

Accepted Answer

A)  It involves memory. 
B)  T lymphocytes play a major role. 
C)  It involves specificity. 
D)  Mechanisms are always present and fully functional. 
A)  It involves memory. 
B)  T lymphocytes play a major role. 
C)  It involves specificity. 
D)  Mechanisms are always present and fully functional.

Question 18

Which of the following best describes diapedesis?

Accepted Answer

A)  Movement toward increasing concentrations of a cytokine 
B)  Attachment of immunoglobulin to target cells 
C)  Movement through blood vessel walls as cells exit the circulation 
D)  Engulfment of target cells 
A)  Movement toward increasing concentrations of a cytokine 
B)  Attachment of immunoglobulin to target cells 
C)  Movement through blood vessel walls as cells exit the circulation 
D)  Engulfment of target cells

Question 19

Which best describes lymph nodes?

Accepted Answer

A)  They line the interior of small blood vessels. 
B)  They are concentrated where appendages join the thorax of the body. 
C)  They are approximately 12 cm in size. 
D)  They are considered primary or central lymphoid organs. 
A)  They line the interior of small blood vessels. 
B)  They are concentrated where appendages join the thorax of the body. 
C)  They are approximately 12 cm in size. 
D)  They are considered primary or central lymphoid organs.

Question 20

Which of the following is NOT a characteristic or function of the spleen?

Accepted Answer

A)  Removes old red blood cells from the circulation 
B)  Filters infectious agents and foreign matter from the blood 
C)  Less than 25 mm in size 
D)  Is considered a secondary lymphoid organ 
A)  Removes old red blood cells from the circulation 
B)  Filters infectious agents and foreign matter from the blood 
C)  Less than 25 mm in size 
D)  Is considered a secondary lymphoid organ

Exam 1: Introduction to Immunity and the Immune System

Which of the following is NOT a characteristic of a lymph node?

All of the following are involved in adaptive immunity EXCEPT:

Which of the following are components of both innate and adaptive immune responses?

A primary site of antigen trapping and presentation to immune cells is the:

Macrophages that migrate to the liver are called:

Match each scientist with the appropriate immunological discovery. -Humoral immunity

Which type of cell has a diameter between 10 and 15 micrometers,has a multi-lobed nucleus,and usually comprises more than 50% of circulating leukocytes?

Which of the following is a characteristic of opsonins?

Innate immunity can be characterized as:

Hematopoietic stem cells are located in the:

Where does the specific immune response to a foreign antigen mainly occur?

T cells mature in the:

Match each scientist with the appropriate immunological discovery. -Vaccination

Which white cell in the peripheral blood migrates into tissue to become a macrophage?

Match each scientist with the appropriate immunological discovery. -Opsonization

A white blood cell that is 16 to 18 micrometers in diameter,has a horseshoe-shaped nucleus,and is capable of phagocytosis is a:

Which of the following is characteristic of natural immunity?

Which of the following best describes diapedesis?

Which best describes lymph nodes?

Which of the following is NOT a characteristic or function of the spleen?

Nature of Antigens and the Major Histocompatibility Complex

Innate Immunity

Adaptive Immunity

Antibody Structure and Function

Cytokines

Complement System

Safety and Quality Management

Principles of Serological Testing

Precipitation and Agglutination Reactions

Labeled Immunoassays

Molecular Diagnostic Techniques

Flow Cytometry and Laboratory Automation

Hypersensitivity

Autoimmunity

Transplantation Immunology

Tumor Immunology

Immunoproliferative Diseases

Immunodeficiency Diseases

Serological and Molecular Detection of Bacterial Infections

Spirochete Diseases

Serological and Molecular Diagnosis of Parasitic and Fungal Infections

Serology and Molecular Detection of Viral Infections

Laboratory Diagnosis of HIV Infection

Immunization and Vaccines

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