Question 1

The CD4 protein is expressed by _______________cells.

Accepted Answer

The answer of The CD4 protein is expressed by _______________cells....

Question 2

The first type of antibody that is found in serum after antigen is detected is

Accepted Answer

A)  IgM. 
B)  IgB. 
C)  IgG. 
D)  IgD. 
E)  IgE. 
A)  IgM. 
B)  IgB. 
C)  IgG. 
D)  IgD. 
E)  IgE.

Question 3

Are unrelated humans likely to have similar class II genes?

Accepted Answer

No.The gen

Question 4

How does the immune response differ for peptides bound to a class II,rather than class I,MHC protein?

Accepted Answer

Peptides bound to class II MHC proteins

Question 5

What type of virus is HIV?

Accepted Answer

A)  retrovirus 
B)  provirus 
C)  oncovirus 
D)  enterovirus 
E)  rotavirus 
A)  retrovirus 
B)  provirus 
C)  oncovirus 
D)  enterovirus 
E)  rotavirus

Question 6

How do large antigens interact with antibodies?

Accepted Answer

A)  The region of contact between antibodies and antigens is very narrow, allowing greater specificity. 
B)  Large antigens will contact the entire antibody, including the Fc region. 
C)  All six CDRs of the antibody can make contact with a specific epitope. 
D)  A single CDR of the antibody contacts multiple epitopes of the antigen. 
E)  None of the answers is correct. 
A)  The region of contact between antibodies and antigens is very narrow, allowing greater specificity. 
B)  Large antigens will contact the entire antibody, including the Fc region. 
C)  All six CDRs of the antibody can make contact with a specific epitope. 
D)  A single CDR of the antibody contacts multiple epitopes of the antigen. 
E)  None of the answers is correct.

Question 7

What is the significance of the J region of the $\kappa$ light-chain locus?

Accepted Answer

A)  Multiple J sites contribute to antibody diversity. 
B)  It provides a unique joining site for J and V genes, which is always the same. 
C)  It provides numerous sites for linkage to the V genes. 
D)  A and B are both correct. 
E)  A and C are both correct. 
A)  Multiple J sites contribute to antibody diversity. 
B)  It provides a unique joining site for J and V genes, which is always the same. 
C)  It provides numerous sites for linkage to the V genes. 
D)  A and B are both correct. 
E)  A and C are both correct.

Question 8

Examples of autoimmune diseases include

Accepted Answer

A)  multiple sclerosis. 
B)  insulin-dependent diabetes mellitus. 
C)  rheumatoid arthritis. 
D)  All of the answers are correct.. 
E)  None of the answers are correct. 
A)  multiple sclerosis. 
B)  insulin-dependent diabetes mellitus. 
C)  rheumatoid arthritis. 
D)  All of the answers are correct.. 
E)  None of the answers are correct.

Question 9

What is the result of the complement cascade?

Accepted Answer

A)  lysis of the target cells 
B)  a series of parallel signal reactions 
C)  destruction of unneeded antibodies 
D)  activation of chemokines 
E)  None of the answers is correct. 
A)  lysis of the target cells 
B)  a series of parallel signal reactions 
C)  destruction of unneeded antibodies 
D)  activation of chemokines 
E)  None of the answers is correct.

Question 10

How is cyclosporin useful in medical therapy?

Accepted Answer

Cyclosporin blocks immune responses by u

Question 11

What types of bonds are present in antigen:antibody binding?

Accepted Answer

The binding involves the interaction of

Question 12

___________________ sequences are recognized by proteins RAG-1 and RAG-2 and facilitate cleavage and religation of DNA segments.

Accepted Answer

Recombinat

Question 13

How is the immune system diversity similar to evolutionary processes?

Accepted Answer

In evolution,there is a mechanism to pro

Question 14

Another name for an antigenic determinant is _______________.

Accepted Answer

The answer of Another name for an antigenic determinant is...

Question 15

_______________ are molecules that induce differentiation,cell growth,and in certain cells,secretion of antibodies.

Accepted Answer

The answer of _______________ are molecules that induce differentiation,cell growth,and...

Question 16

MHC class I and II proteins bind and present _______________ to T cells.

Accepted Answer

The answer of MHC class I and II proteins bind...

Question 17

Which antibody can cause allergic reactions?

Accepted Answer

A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM 
A)  IgA 
B)  IgD 
C)  IgE 
D)  IgG 
E)  IgM

Question 18

What are the two lines of defense in our immune system?

Accepted Answer

The innate immune system respo

Question 19

What are positive and negative selection of T-cell receptors?

Accepted Answer

Positive selection removes T c

Question 20

What are the proteases released by cytotoxic T cells that initiate the apoptotic cascade in virus-infected cells?

Accepted Answer

A)  caspases 
B)  cathepsins 
C)  granzymes 
D)  calpains 
E)  None of the answers is correct. 
A)  caspases 
B)  cathepsins 
C)  granzymes 
D)  calpains 
E)  None of the answers is correct.

Exam 34: The Immune System

The CD4 protein is expressed by _______________cells.

The first type of antibody that is found in serum after antigen is detected is

Are unrelated humans likely to have similar class II genes?

How does the immune response differ for peptides bound to a class II,rather than class I,MHC protein?

What type of virus is HIV?

How do large antigens interact with antibodies?

What is the significance of the J region of the κ\kappaκ light-chain locus?

Examples of autoimmune diseases include

What is the result of the complement cascade?

How is cyclosporin useful in medical therapy?

What types of bonds are present in antigen:antibody binding?

___________________ sequences are recognized by proteins RAG-1 and RAG-2 and facilitate cleavage and religation of DNA segments.

How is the immune system diversity similar to evolutionary processes?

Another name for an antigenic determinant is _______________.

_______________ are molecules that induce differentiation,cell growth,and in certain cells,secretion of antibodies.

MHC class I and II proteins bind and present _______________ to T cells.

Which antibody can cause allergic reactions?

What are the two lines of defense in our immune system?

What are positive and negative selection of T-cell receptors?

What are the proteases released by cytotoxic T cells that initiate the apoptotic cascade in virus-infected cells?

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

Biosynthesis of Membrane Lipids and Steroids

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

Molecular Motors

Drug Development

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What is the significance of the J region of the $\kappa$ light-chain locus?