Question 1

The LDL receptors on the plasma membrane are localized in coated pits that contain which of the following proteins?

Accepted Answer

A)  clathrin 
B)  lipoprotein B-100 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  SREBP, sterol regulatory element binding protein 
A)  clathrin 
B)  lipoprotein B-100 
C)  adrenodoxin 
D)  HMG-CoA reductase 
E)  SREBP, sterol regulatory element binding protein

Question 2

Which of the following combines with glycine to form a major bile salt?

Accepted Answer

A)  phosphatidate 
B)  phosphatidylethanolamine 
C)  glycerol 
D)  cholesterol 
E)  phosphatidylserine 
A)  phosphatidate 
B)  phosphatidylethanolamine 
C)  glycerol 
D)  cholesterol 
E)  phosphatidylserine

Question 3

Which of the following is a principal component of the lipid-rich covering on neuronal axons?

Accepted Answer

A)  vitamin A 
B)  phosphatidylserine 
C)  sphingomyelin 
D)  triacylglycerol 
E)  None of the answers is correct. 
A)  vitamin A 
B)  phosphatidylserine 
C)  sphingomyelin 
D)  triacylglycerol 
E)  None of the answers is correct.

Question 4

Which of the following vitamins is a derivative of cholesterol?

Accepted Answer

A)  vitamin A 
B)  vitamin D 
C)  vitamin E 
D)  vitamin K 
E)  None of the answers is correct. 
A)  vitamin A 
B)  vitamin D 
C)  vitamin E 
D)  vitamin K 
E)  None of the answers is correct.

Question 5

Tay-Sachs disease is caused by an inability to degrade

Accepted Answer

A)  sphingosine. 
B)  gangliosides. 
C)  dipalmitoyl phosphatidyl choline. 
D)  ceramide. 
E)  None of the answers is correct. 
A)  sphingosine. 
B)  gangliosides. 
C)  dipalmitoyl phosphatidyl choline. 
D)  ceramide. 
E)  None of the answers is correct.

Question 6

A ___________________ is composed of a fatty acid linked to sphingosine via an amide bond.

Accepted Answer

The answer of A ___________________ is composed of a fatty...

Question 7

Why are phosphatidylserine,and most other phospholipids,considered classes of molecules,rather than a single molecule?

Accepted Answer

Because various fatty acid gro

Question 8

Vitamin D3 is converted into ______________________,which is an active hormone that functions as a transcription factor.

Accepted Answer

calcitriol

Question 9

What is the role of cytochrome P450 monooxygenases in steroid biosynthesis?

Accepted Answer

The formation of cholesterol and its con

Question 10

The synthesis of ____________________ is the committed step in cholesterol biosynthesis.

Accepted Answer

The answer of The synthesis of ____________________ is the committed...

Question 11

What metabolite is reduced to glycerol-3-phosphate for triacylglycerol synthesis?

Accepted Answer

A)  glyceraldehyde-3-phosphate 
B)  3-phosphoglycerate 
C)  phosphoenolpyruvate 
D)  dihydroxyacetone phosphate 
E)  None of the answers is correct. 
A)  glyceraldehyde-3-phosphate 
B)  3-phosphoglycerate 
C)  phosphoenolpyruvate 
D)  dihydroxyacetone phosphate 
E)  None of the answers is correct.

Question 12

In the biosynthesis of phosphatidates,the fatty acyl group attached to the C-2 position is usually ______________________.

Accepted Answer

The answer of In the biosynthesis of phosphatidates,the fatty acyl...

Question 13

In the biosynthesis of sphingosine,the condensation of palmitoyl CoA and serine requires the coenzyme ____________________.

Accepted Answer

PLP,pyrido

Question 14

What is the role of phosphatidyl choline in the synthesis of sphingomyelin?

Accepted Answer

Phosphatidyl choline supplies

Question 15

______________________ is the major carrier of cholesterol esters in the blood.

Accepted Answer

Low-densit

Question 16

Which lipoprotein transports lipids away from the intestine?

Accepted Answer

A)  chylomicron 
B)  very low density lipoprotein 
C)  low-density lipoprotein 
D)  high density lipoprotein 
E)  None of the answers is correct. 
A)  chylomicron 
B)  very low density lipoprotein 
C)  low-density lipoprotein 
D)  high density lipoprotein 
E)  None of the answers is correct.

Question 17

What are bile salts?

Accepted Answer

Bile salts are amphiphilic derivatives o

Question 18

List the types of lipoprotein particles,and give the primary physiological role of the lipoprotein.See Table 26.1Lipoprotein Physiological function

Accepted Answer

chylomicrons transport dietary fat
very

Question 19

Feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme

Accepted Answer

A)  3-hydroxy-3-methylglutaryl CoA reductase. 
B)  geranyltransferase. 
C)  HMG transferase. 
D)  farnesyl reductase. 
E)  None of the answers is correct. 
A)  3-hydroxy-3-methylglutaryl CoA reductase. 
B)  geranyltransferase. 
C)  HMG transferase. 
D)  farnesyl reductase. 
E)  None of the answers is correct.

Question 20

Respiratory distress syndrome is caused by a failure in the biosynthetic pathway of

Accepted Answer

A)  sphingosine. 
B)  gangliosides. 
C)  dipalmitoyl phosphatidyl choline. 
D)  cholesterol. 
E)  bile salts. 
A)  sphingosine. 
B)  gangliosides. 
C)  dipalmitoyl phosphatidyl choline. 
D)  cholesterol. 
E)  bile salts.

Exam 26: Biosynthesis of Membrane Lipids and Steroids

The LDL receptors on the plasma membrane are localized in coated pits that contain which of the following proteins?

Which of the following combines with glycine to form a major bile salt?

Which of the following is a principal component of the lipid-rich covering on neuronal axons?

Which of the following vitamins is a derivative of cholesterol?

Tay-Sachs disease is caused by an inability to degrade

A ___________________ is composed of a fatty acid linked to sphingosine via an amide bond.

Why are phosphatidylserine,and most other phospholipids,considered classes of molecules,rather than a single molecule?

Vitamin D3 is converted into ______________________,which is an active hormone that functions as a transcription factor.

What is the role of cytochrome P450 monooxygenases in steroid biosynthesis?

The synthesis of ____________________ is the committed step in cholesterol biosynthesis.

What metabolite is reduced to glycerol-3-phosphate for triacylglycerol synthesis?

In the biosynthesis of phosphatidates,the fatty acyl group attached to the C-2 position is usually ______________________.

In the biosynthesis of sphingosine,the condensation of palmitoyl CoA and serine requires the coenzyme ____________________.

What is the role of phosphatidyl choline in the synthesis of sphingomyelin?

______________________ is the major carrier of cholesterol esters in the blood.

Which lipoprotein transports lipids away from the intestine?

What are bile salts?

List the types of lipoprotein particles,and give the primary physiological role of the lipoprotein.See Table 26.1Lipoprotein Physiological function

Feedback regulation of cholesterol synthesis is mainly controlled at the step catalyzed by the enzyme

Respiratory distress syndrome is caused by a failure in the biosynthetic pathway of

Biochemistry: An Evolving Science

Protein Composition and Structure

Exploring Proteins and Proteomes

DNA, RNA, and the Flow of Genetic Information

Exploring Genes and Genomes

Exploring Evolution and Bioinformatics

Hemoglobin: a Portrait of a Protein in Action

Enzymes: Basic Concepts and Kinetics

Catalytic Strategies

Regulatory Strategies

Carbohydrates

Lipids and Cell Membranes

Membrane Channels and Pumps

Signal-Transduction Pathways

Metabolism: Basic Concepts and Design

Glycolysis and Gluconeogenesis

The Citric Acid Cycle

Oxidative Phosphorylation

The Light Reactions of Photosynthesis

The Calvin Cycle and the Pentose Phosphate Pathway

Glycogen Metabolism

Fatty Acid Metabolism

Protein Turnover and Amino Acid Catabolism

The Biosynthesis of Amino Acids

Nucleotide Biosynthesis

The Integration of Metabolism

DNA Replication, repair, and Recombination

RNA Synthesis and Processing

Protein Synthesis

The Control of Gene Expression in Prokaryotes

The Control of Gene Expression in Eukaryotes

Sensory Systems

The Immune System

Molecular Motors

Drug Development

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Vitamin D₃ is converted into ______________________,which is an active hormone that functions as a transcription factor.